ycbC

ycbC
168

5-dehydro-4-deoxyglucarate dehydratase

Locus
BSU_02460
Molecular weight
33.89 kDa
Isoelectric point
5.38
Protein length
Gene length
Function
utilization of D-glucarate/galactarate
Product
5-dehydro-4-deoxyglucarate dehydratase
Essential
no
E.C.
4.2.1.41
Synonyms
ycbC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0329 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
267,890  268,816
The protein
Catalyzed reaction/ biological activity
5-dehydro-4-deoxy-D-glucarate + H+ --> 2,5-dioxopentanoate + CO2 + H2O (according to UniProt)
Protein family
DapA family (with DapA, according to UniProt)
Structure
4UR8 (PDB) (from Agrobacterium fabrum, 38% identity) PubMed
Expression and Regulation
Operons
Description
Regulation
induced by D-glucarate/galactarate (YcbG) PubMed
Regulatory mechanism
YcbG: repression, PubMed, in ycbG regulon
AbrB: repression, PubMed, in abrB regulon
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ycbCycbJ

2025-01-11 11:08:44

ghost

120

a8e395a36da4d417bafa3e16f332fbbf2dcf2e61

24EBFC92FB6A93BD115AC81FF68694FB539EE76E

Biological materials
Mutant
MGNA-C027 (ycbC::erm), available at the NBRP B. subtilis, Japan
BKE02460 (ycbC::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCAACATAACCTCCTGTT,  downstream forward: _UP4_TGACCAGAAAAAACACGAAA
BKK02460 (ycbC::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCAACATAACCTCCTGTT,  downstream forward: _UP4_TGACCAGAAAAAACACGAAA
References
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3542BC20C11985B3CFAA4F930E8D794700ADFD2E

Page visits: 1897

Time of last update: 2025-01-17 17:57:55

Author of last update: Melvin.boenninger