spoIIB

spoIIB
168

spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment

Locus
BSU_28060
Molecular weight
35.77 kDa
Isoelectric point
4.8
Protein length
332 aaSequenceBlast
Gene length
999 bpSequenceBlast
Function
spore morphogenesis
Product
facilitator of septal dissolution
Essential
no
E.C.
null
Synonyms
spoIIB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5816 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,863,294 → 2,864,292
Phenotypes of a mutant
reduced sporulation frequency (10 to 20-fold) PubMed
slow and inefficient spore engulfment PubMed
The protein
Catalyzed reaction/ biological activity
required for efficient localization of the SpoIID-SpoIIM-SpoIIP complex to the septal membrane PubMed
Domains
SPOR domain (aa 175-250) (according to UniProt)
Structure
P37575 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
spoIIB
Description
PubMed
Regulation
expression is reduced in a SigV mutant PubMed
Sigma factors
SigV: sigma factor, in sigV regulon
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spoIIB

2025-03-11 19:20:55

ghost

75

613aca2467317449239594c4b7c3f89c11d62127

431135D9B1477154B2CFD0226BD0E3FFFBECC13F

Biological materials
Mutant
BKE28060 (ΔspoIIB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATTCCGCTTCCTCCCTTC,  downstream forward: _UP4_TAAGAGATAGTGCCCTGAGC
BKK28060 (ΔspoIIB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATTCCGCTTCCTCCCTTC,  downstream forward: _UP4_TAAGAGATAGTGCCCTGAGC
References
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D98D61CA651AAA415386B1B2B41562E5CF77DEF1

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Time of last update: 2025-04-12 10:30:10

Author of last update: Jstuelk