Difference between revisions of "G-box"

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The G-box element is a [[riboswitch]] that controls different genes of purine nucleotide metabolism in  response to the presence of guanine.
 
The G-box element is a [[riboswitch]] that controls different genes of purine nucleotide metabolism in  response to the presence of guanine.
  
Genes controlled by G-box element:
+
Genes controlled by a G-box element:
  
 
* ''[[xpt]]''-''[[pbuX]]''
 
* ''[[xpt]]''-''[[pbuX]]''
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* ''[[purE]]-[[purK]]-[[purB]]-[[purC]]-[[purS]]-[[purQ]]-[[purL]]-[[purF]]-[[purM]]-[[purN]]-[[purH]]-[[purD]]''
 
* ''[[purE]]-[[purK]]-[[purB]]-[[purC]]-[[purS]]-[[purQ]]-[[purL]]-[[purF]]-[[purM]]-[[purN]]-[[purH]]-[[purD]]''
  
 +
==Structure of a G-box riboswitch==
 +
* [http://www.rcsb.org/pdb/explore/explore.do?pdbId=2XO1 2XO1]  {{PubMed|21439477}}
  
 
==References==
 
==References==
 +
<pubmed> 12787499 ,18072940 19603494 19739679 20022916 20200045 20204714 21439477 21890900,26704707,27941758,28541183</pubmed>
  
<pubmed> 12787499 ,18072940 </pubmed>
+
=See also:=
 +
* [[RNA switch]]
 +
 
 +
=Back to [[regulons]]=

Latest revision as of 15:23, 26 May 2017

The G-box element is a riboswitch that controls different genes of purine nucleotide metabolism in response to the presence of guanine.

Genes controlled by a G-box element:

Structure of a G-box riboswitch

References

Hannah Steinert, Florian Sochor, Anna Wacker, Janina Buck, Christina Helmling, Fabian Hiller, Sara Keyhani, Jonas Noeske, Steffen Grimm, Martin M Rudolph, Heiko Keller, Rachel Anne Mooney, Robert Landick, Beatrix Suess, Boris Fürtig, Jens Wöhnert, Harald Schwalbe
Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation.
Elife: 2017, 6;
[PubMed:28541183] [WorldCat.org] [DOI] (I e)

Vishnu Chandra, Zain Hannan, Huizhong Xu, Maumita Mandal
Single-molecule analysis reveals multi-state folding of a guanine riboswitch.
Nat Chem Biol: 2017, 13(2);194-201
[PubMed:27941758] [WorldCat.org] [DOI] (I p)

F Sochor, R Silvers, D Müller, C Richter, B Fürtig, H Schwalbe
(19)F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy.
J Biomol NMR: 2016, 64(1);63-74
[PubMed:26704707] [WorldCat.org] [DOI] (I p)

Janina Buck, Anna Wacker, Eberhart Warkentin, Jens Wöhnert, Julia Wirmer-Bartoschek, Harald Schwalbe
Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain.
Nucleic Acids Res: 2011, 39(22);9768-78
[PubMed:21890900] [WorldCat.org] [DOI] (I p)

Peter Daldrop, Francis E Reyes, David A Robinson, Colin M Hammond, David M Lilley, Robert T Batey, Ruth Brenk
Novel ligands for a purine riboswitch discovered by RNA-ligand docking.
Chem Biol: 2011, 18(3);324-35
[PubMed:21439477] [WorldCat.org] [DOI] (I p)

Otmar M Ottink, Ivo M Westerweele, Marco Tesssari, Frank H T Nelissen, Hans A Heus, Sybren S Wijmenga
1H and 13C resonance assignments of a guanine sensing riboswitch's terminator hairpin.
Biomol NMR Assign: 2010, 4(1);89-91
[PubMed:20204714] [WorldCat.org] [DOI] (I p)

Janina Buck, Jonas Noeske, Jens Wöhnert, Harald Schwalbe
Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain.
Nucleic Acids Res: 2010, 38(12);4143-53
[PubMed:20200045] [WorldCat.org] [DOI] (I p)

Vanessa Delfosse, Patricia Bouchard, Eric Bonneau, Pierre Dagenais, Jean-François Lemay, Daniel A Lafontaine, Pascale Legault
Riboswitch structure: an internal residue mimicking the purine ligand.
Nucleic Acids Res: 2010, 38(6);2057-68
[PubMed:20022916] [WorldCat.org] [DOI] (I p)

Jane N Kim, Kenneth F Blount, Izabela Puskarz, Jinsoo Lim, Kristian H Link, Ronald R Breaker
Design and antimicrobial action of purine analogues that bind Guanine riboswitches.
ACS Chem Biol: 2009, 4(11);915-27
[PubMed:19739679] [WorldCat.org] [DOI] (I p)

Oksana Prychyna, Michael S Dahabieh, Jay Chao, Melanie A O'Neill
Sequence-dependent folding and unfolding of ligand-bound purine riboswitches.
Biopolymers: 2009, 91(11);953-65
[PubMed:19603494] [WorldCat.org] [DOI] (P p)

Jane N Kim, Ronald R Breaker
Purine sensing by riboswitches.
Biol Cell: 2008, 100(1);1-11
[PubMed:18072940] [WorldCat.org] [DOI] (I p)

Maumita Mandal, Benjamin Boese, Jeffrey E Barrick, Wade C Winkler, Ronald R Breaker
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.
Cell: 2003, 113(5);577-86
[PubMed:12787499] [WorldCat.org] [DOI] (P p)


See also:

Back to regulons