fruK

fruK
168

fructose-1-phosphate kinase

Locus
BSU_14390
Molecular weight
32.64 kDa
Isoelectric point
4.89
Protein length
303 aaSequenceBlast
Gene length
912 bpSequenceBlast
Function
fructose utilization
Product
fructose-1-phosphate kinase
Essential
no
E.C.
2.7.1.56
Synonyms
fruK, fruB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1105 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,508,330  1,509,241
The protein
Catalyzed reaction/ biological activity
ATP + β-D-fructose 1-phosphate --> ADP + β-D-fructose 1,6-bisphosphate + H+ (according to UniProt)
Protein family
carbohydrate kinase PfkB family (according to UniProt)
Structure
3OHR (PDB)
O31714 (AlphaFold)
Expression and Regulation
Operons
Genes
fruR-fruK-fruA
Description
PubMed
Regulation
induced in the presence of fructose (FruR) (according to DBTBS)
Regulatory mechanism
FruR: repression, (according to DBTBS), in fruR regulon
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fruR→fruA

2025-04-02 10:00:03

Jstuelk

62

9f213a6a542b751d6071879bc2e09beaf0921706

443DDA78EBE750032AAAB5DBAD29D489008CAE5D

Biological materials
Mutant
BKE14390 (fruK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT,  downstream forward: _UP4_CGTCTATAGAGGAGGAAACA
BKK14390 (fruK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGGATTAAGTGTTACAGTGT,  downstream forward: _UP4_CGTCTATAGAGGAGGAAACA
References
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502AA809C8C95F8886DD91FBB7DDBECC63342327

Page visits: 2530

Time of last update: 2025-04-18 15:35:13

Author of last update: Melvin.boenninger