radC

radC
168

probable DNA repair protein

Locus
BSU_28040
Molecular weight
26.00 kDa
Isoelectric point
7.83
Protein length
231 aaSequenceBlast
Gene length
696 bpSequenceBlast
Function
DNA repair
Product
probable DNA repair protein
Essential
no
Synonyms
radC, ysxA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2003 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,861,840  2,862,535
The protein
Protein family
UPF0758 family (single member, according to UniProt)
Domains
MPN domain (aa 109-231) (according to UniProt)
Structure
2QLC (PDB) (C-terminal domain of Chlorobium tepidum RadC, 46% identity)
Q02170 (AlphaFold)
Modification
phosphorylated on Arg-59 PubMed
Localization
cytoplasm (Homogeneous) PubMed
Expression and Regulation
Operons
Genes
maf-radC-mreB-mreC-mreD-minC-minD
Description
PubMed
Regulation
constitutively expressed PubMed
Regulatory mechanism
ComK: activation, PubMed, in comK regulon
Sigma factors
SigM: sigma factor, promoter p2 within Maf PubMed, in sigM regulon
SigA: sigma factor, promoter p1, upstream of Maf PubMed, in sigA regulon
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maf→minD

2025-04-03 12:26:20

ghost

139

5cb36570cb9eb74ac55107ce2bd7f07e7d2d5c0b

EE31E7A5D1B0C8BDC56B004AA68A1C721D4DA9CC

Biological materials
Mutant
GP3561 (ΔradC::aphA3), available in Jörg Stülke's lab
MGNA-B011 (ysxA::erm), available at the NBRP B. subtilis, Japan
BKE28040 (radC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGCACTCCTTTTCTTTCC,  downstream forward: _UP4_TAACACTTTTTTTTTCGTCG
BKK28040 (radC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGCACTCCTTTTCTTTCC,  downstream forward: _UP4_TAACACTTTTTTTTTCGTCG
References
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2BD11D71AA6D9EFAD8A209C8813CC8B059180C84

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Time of last update: 2025-04-05 01:13:15

Author of last update: MBenda