mpr

mpr
168

extracellular metalloprotease

Locus
BSU_02240
Molecular weight
33.69 kDa
Isoelectric point
8.97
Protein length
313 aaSequenceBlast
Gene length
942 bpSequenceBlast
Function
protein degradation
Product
extracellular metalloprotease
Essential
no
Synonyms
mpr
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3591 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
245,190  246,131
The protein
Protein family
peptidase S1B family (single member, according to UniProt)
Structure
1P3C (PDB) (from B. intermedius, corresponds to aa 95 ... 289, 31% identity) PubMed
P39790 (AlphaFold)
Localization
extracellular (signal peptide) PubMed
Expression and Regulation
Operons
Genes
mpr-ybfJ
Description
PubMed
Regulation
repressed by casamino acids PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
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mpr→ybfJ

2025-03-16 04:56:44

ghost

130

c94f708bb33d19ebb7718a8e2cca7da24f7d075f

F0A001416ED39498CAC09F0DF093E069C2540398

Biological materials
Mutant
KO7 (nprE  aprE  epr  mpr  nprB  vpr  bpr), available as BGSC 1A1133
BKE02240 (mpr::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT,  downstream forward: _UP4_AACTTGGGAACAAGGGTGAC
BKK02240 (mpr::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTGTCATCTCCCTCCT,  downstream forward: _UP4_AACTTGGGAACAAGGGTGAC
References
Reviews
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Original Publications
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A39D349BBE13F4F3F6D33DA72CB8149A5170255C

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Time of last update: 2025-03-15 13:28:35

Author of last update: Jstuelk