opuAC

opuAC
168

glycine betaine and arsenobetaine ABC transporter (binding protein)

Locus
BSU_03000
Molecular weight
32.06 kDa
Isoelectric point
8.02
Protein length
293 aaSequenceBlast
Gene length
882 bpSequenceBlast
Function
compatible solute transport
Product
glycine betaine and arsenobetaine ABC transporter (binding protein)
Essential
no
Synonyms
opuAC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2113 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
323,119  324,000
The protein
Catalyzed reaction/ biological activity
binding for subsequent uptake of glycine betaine and arsenobetaine PubMed
binding for subsequent uptake of dimethylglycine PubMed
Structure
2B4L (PDB) (complex with glycine betaine)
3CHG (PDB) (in complex with DMSA)
5NXX (PDB) (in complex with arsenobetaine) PubMed
P46922 (AlphaFold)
Localization
associated to the membrane (via OpuAB) PubMed
Expression and Regulation
Operons
Genes
opuAA-opuAB-opuAC
Description
PubMed
Regulation
induced by osmotic stress PubMed
Regulatory mechanism
RemA: activation, PubMed, in remA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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opuAA→opuAC

2025-04-04 06:52:03

ghost

116

eafb0a634093d79d1a26ed7a049acac8747a3e05

204CCFDF8D1DFA897A97ACEDDC7D4A3EDDBDB61A

Biological materials
Mutant
BKE03000 (opuAC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GATGCCTATGATTTTTTTAA,  downstream forward: _UP4_TAATCAAAAAAGCAGCCTGT
BKK03000 (opuAC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GATGCCTATGATTTTTTTAA,  downstream forward: _UP4_TAATCAAAAAAGCAGCCTGT
Expression vectors
pGP2926 (N-terminal His-tag, purification from E. coli, in pWH844), available in Jörg Stülke's lab
Labs working on this gene/protein
Erhard Bremer, University of Marburg, Germany homepage
References
Reviews
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Original Publications
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546407EFD8128D1F74443991B8D600F668FBD7A1

Page visits: 3495

Time of last update: 2025-04-03 20:05:01

Author of last update: Jstuelk