gmuC

gmuC
168

glucomannan-specific permease of the phosphotransferase system, EIIC of the PTS

Locus
BSU_05830
Molecular weight
48.27 kDa
Isoelectric point
9.8
Protein length
442 aaSequenceBlast
Gene length
1329 bpSequenceBlast
Function
glucomannan uptake and phosphorylation
Product
glucomannan-specific lichenan-specific PTS, EIIC component
Essential
no
Synonyms
gmuC, ydhO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1455 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
627,284  628,612
The protein
Protein family
PTS permease, lactose family PubMed
Domains
PTS EIIC domain type-3 (aa 5-411) (according to UniProt)
Structure
3QNQ (PDB) (EIIC component of diacetylchitobiose specific PTS from Bacillus cereus; 41% identity, 80% similarity) PubMed
O05507 (AlphaFold)
Paralogous protein(s)
LicC, YwbA
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
Description
PubMed
Regulation
induced by cellobiose (GmuR) PubMed
Regulatory mechanism
GmuR: repression, PubMed, in gmuR regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

gmuB→gmuG

2025-03-16 15:57:23

Jstuelk

109

1716709ba10a9af523abc0d89eb44ea784dd12d9

42FBC6CD7712CC913DB98C4B417CB4A13C8FAE20

Additional information
translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
Biological materials
Mutant
MGNA-C190 (ydhO::erm), available at the NBRP B. subtilis, Japan
BKE05830 (gmuC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GAACACCCTATCCACCCCGA,  downstream forward: _UP4_ATGTGACATAAGGGGAGAGA
BKK05830 (gmuC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GAACACCCTATCCACCCCGA,  downstream forward: _UP4_ATGTGACATAAGGGGAGAGA
References
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76324E0A6CAA8E1DD0B0C6FAE1CAB402231BF7CC

Page visits: 5955

Time of last update: 2025-04-08 06:36:03

Author of last update: Melvin.boenninger