RCK C domain

This domain is found in several potassium transporters.

• For more information, see InterPro
• RCK_C domain-containing protein usually bind c-di-AMP PubMed

B. subtilis proteins containing a RCK_C domain

• KtrA
• KtrC
• KhtT
• YjbQ
• YrvC

Related SubtiWiki pages

• Metal ion homeostasis (K, Na, Ca, Mg)
• RCK N domain
• Targets of c-di-AMP

Important publications

Marina Schrecker, Dorith Wunnicke, Inga Hänelt
How RCK domains regulate gating of K+ channels.
Biol Chem: 2019, 400(10);1303-1322
[PubMed:31361596] [WorldCat.org] [DOI] (I p)

Jan Gundlach, Larissa Krüger, Christina Herzberg, Asan Turdiev, Anja Poehlein, Igor Tascón, Martin Weiss, Dietrich Hertel, Rolf Daniel, Inga Hänelt, Vincent T Lee, Jörg Stülke
Sustained sensing in potassium homeostasis: Cyclic di-AMP controls potassium uptake by KimA at the levels of expression and activity.
J Biol Chem: 2019, 294(24);9605-9614
[PubMed:31061098] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Achim Dickmanns, Jan Gundlach, Ralf Ficner, Jörg Stülke
A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.
Mol Microbiol: 2015, 97(2);189-204
[PubMed:25869574] [WorldCat.org] [DOI] (I p)

Rebecca M Corrigan, Ivan Campeotto, Tharshika Jeganathan, Kevin G Roelofs, Vincent T Lee, Angelika Gründling
Systematic identification of conserved bacterial c-di-AMP receptor proteins.
Proc Natl Acad Sci U S A: 2013, 110(22);9084-9
[PubMed:23671116] [WorldCat.org] [DOI] (I p)

Ronald A Albright, José-Luís Vazquez Ibar, Chae Un Kim, Sol M Gruner, João Henrique Morais-Cabral
The RCK domain of the KtrAB K+ transporter: multiple conformations of an octameric ring.
Cell: 2006, 126(6);1147-59
[PubMed:16990138] [WorldCat.org] [DOI] (P p)