fecF

fecF
168

iron/citrate ABC transporter (ATP-binding protein)

Locus
BSU_07490
Molecular weight
29.31 kDa
Isoelectric point
6.07
Protein length
Gene length
Function
iron uptake
Product
iron/citrate ABC transporter (ATP-binding protein)
Essential
no
E.C.
3.6.3.-
Synonyms
fecF, yfmF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1120 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
822,903 → 823,703
The protein
Protein family
ABC transporter superfamily (according to UniProt)
ABC transporter domain (aa 4-240) (according to UniProt)
Structure
4G1U (PDB) (from Yersinia pestis, the FecD-FecE-FecF complex, 32% identity) PubMed
Paralogous protein(s)
associated to the membrane (via FecD-FecE) PubMed
Expression and Regulation
Operons
Description
Regulation
immediately induced upon iron starvation (first wave to allow iron uptake) (Fur) PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
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fecCfecF

2024-12-21 13:13:32

Jstuelk

56

08d0c1575e8a6211c799093cfc6ee3a9c3135a88

49520E691347BD8533B6CD8A50C6130F3DA7A9DB

Biological materials
Mutant
MGNA-C244 (yfmF::erm), available at the NBRP B. subtilis, Japan
BKE07490 (ΔfecF::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAGTTTTCCCATGGTATCCT,  downstream forward: _UP4_TGAAAAGGAGAGGAATTCCC
BKK07490 (ΔfecF::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAGTTTTCCCATGGTATCCT,  downstream forward: _UP4_TGAAAAGGAGAGGAATTCCC
References
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Time of last update: 2025-01-06 09:58:31

Author of last update: Jstuelk