cydC

cydC
168

ABC transporter required for expression of cytochrome bd (membrane protein)

Locus
BSU_38740
Molecular weight
62.63 kDa
Isoelectric point
8.51
Protein length
567 aaSequenceBlast
Gene length
1704 bpSequenceBlast
Function
required for expression of cytochrome bd
Product
ABC transporter  (membrane protein)
Essential
no
Synonyms
cydC, yxkM
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4988 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,975,088  3,976,791
The protein
Protein family
ABC transporter superfamily (according to UniProt)
Domains
has both a membrane-spanning and an ATP-binding domain PubMed
ABC transmembrane type-1 domain (aa 15-298) (according to UniProt)
ABC transporter domain (aa 321-561) (according to UniProt)
Structure
2HYD (PDB) (from Staphylococcus aureus, 27% identity) PubMed
P94366 (AlphaFold)
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
cydA-cydB-cydC-cydD
Description
PubMed
Regulation
expressed under anaerobic conditions (ResD) PubMed
Expression
expression is heterogeneous PubMed
Regulatory mechanism
CcpA: repression, in ccpA regulon
Rex: repression, PubMed, in rex regulon
ResD: activation, PubMed, in resD regulon
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
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cydA→cydD

2025-03-17 19:43:41

Jstuelk

121

B656DC522BB35F8FB6BB0C0BBC86CB05C20AB7C7

80895031322ED50D8EABA337924455145A6261DF

Biological materials
Mutant
MGNA-B747 (cydC::erm), available at the NBRP B. subtilis, Japan
BKE38740 (cydC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATATCGAAACAGGTCTTTTC,  downstream forward: _UP4_AAGGCACAACTGGGGGAAAG
BKK38740 (cydC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATATCGAAACAGGTCTTTTC,  downstream forward: _UP4_AAGGCACAACTGGGGGAAAG
References
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A65576E0261F1950A0DAD72B2432D97AB3EB2AA5

Page visits: 5151

Time of last update: 2025-04-08 20:44:14

Author of last update: Jstuelk