Difference between revisions of "RatA"
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|style="background:#ABCDEF;" align="center"| '''Gene length''' || 222 bp | |style="background:#ABCDEF;" align="center"| '''Gene length''' || 222 bp | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[txpA]]'', ''[[bsrH]]'' |
|- | |- | ||
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt Gene sequence (+200bp) ]''' | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt Gene sequence (+200bp) ]''' | ||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:genE_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:genE_context.gif]] | ||
| + | |- | ||
| + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=S976_2678362_2678577_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ratA_expression.png|500px]] | ||
|- | |- | ||
|} | |} | ||
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<br/><br/> | <br/><br/> | ||
| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}}, | ||
| + | {{SubtiWiki category|[[Skin element]]}}, | ||
| + | {{SubtiWiki category|[[ncRNA]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | |||
| + | =The [[ratA regulon]]: ''[[txpA]]'' = | ||
=The gene= | =The gene= | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?] | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The RNA= | =The RNA= | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
| + | ** the ''[[txpA]]'' mRNA-''[[RatA]]'' RNA duplex is degraded by [[rnc|RNase III]] {{PubMed|23300471}} | ||
=Biological materials = | =Biological materials = | ||
| Line 86: | Line 96: | ||
=References= | =References= | ||
| + | ==Reviews== | ||
| + | <pubmed> 23300472 </pubmed> | ||
| − | <pubmed>16166525, </pubmed> | + | ==Original publications== |
| + | <pubmed>16166525, 23300471</pubmed> | ||
[[Category:small RNA]] | [[Category:small RNA]] | ||
Latest revision as of 12:06, 28 January 2017
| Gene name | ratA |
| Synonyms | |
| Essential | no |
| Product | txpA antisense RNA |
| Function | control of txpA expression |
| Gene length | 222 bp |
| Immediate neighbours | txpA, bsrH |
| Gene sequence (+200bp) | |
| Genetic context File:GenE context.gif | |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins, Skin element, ncRNA
This gene is a member of the following regulons
The ratA regulon: txpA
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry:
- Structure:
Additional information
The RNA
binds the txpA mRNA and triggers its degradation PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard University, Cambridge, USA Homepage
Your additional remarks
References
Reviews
Original publications
Sylvain Durand, Laetitia Gilet, Ciarán Condon
The essential function of B. subtilis RNase III is to silence foreign toxin genes.
PLoS Genet: 2012, 8(12);e1003181
[PubMed:23300471]
[WorldCat.org]
[DOI]
(I p)
Jessica M Silvaggi, John B Perkins, Richard Losick
Small untranslated RNA antitoxin in Bacillus subtilis.
J Bacteriol: 2005, 187(19);6641-50
[PubMed:16166525]
[WorldCat.org]
[DOI]
(P p)
