Difference between revisions of "ComN"
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|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence and DNA uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence and DNA uptake | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27660 comN] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ComN ComN] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 4.622 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 4.622 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[secDF]]'', ''[[spoVB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[secDF]]'', ''[[spoVB]]'' | ||
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27660 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27660 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27660 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yrzD_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yrzD_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comN_2829152_2829448_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:comN_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27660]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
<br/><br/> | <br/><br/> | ||
+ | = [[Categories]] containing this gene/protein = | ||
+ | {{SubtiWiki category|[[genetic competence]]}}, | ||
+ | {{SubtiWiki category|[[membrane proteins]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
+ | |||
+ | =The [[ComN regulon]]: ''[[comEA]]-[[comEB]]-[[comEC]]''= | ||
=The gene= | =The gene= | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27660&redirect=T BSU27660] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Additional information=== | === Additional information=== | ||
− | |||
=The protein= | =The protein= | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' post-transcriptional control of ''[[comEA]]'' expression [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed] | + | * '''Catalyzed reaction/ biological activity:''' |
− | + | ** post-transcriptional control of ''[[comEA]]'' expression [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed] | |
+ | ** promotes the accumulation of its target ''[[comEA]]'' mRNA to septal and polar sites {{PubMed|22582279}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
+ | ** [[DivIVA]]-[[ComN]] {{PubMed|22582279}} | ||
− | * '''Localization:''' cell | + | * '''[[Localization]]:''' |
+ | ** localizes to the division site and cell poles in a [[DivIVA]] dependent fashion {{PubMed|22582279}} | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27660&redirect=T BSU27660] | ||
* '''Structure:''' | * '''Structure:''' | ||
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* '''Operon:''' | * '''Operon:''' | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comN_2829152_2829448_-1 comN] {{PubMed|22383849}} |
+ | |||
+ | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
+ | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 140 {{PubMed|24696501}} | ||
=Biological materials = | =Biological materials = | ||
Line 118: | Line 141: | ||
=References= | =References= | ||
− | <pubmed>19028902, | + | <pubmed>19028902,22582279, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Latest revision as of 09:57, 17 April 2014
- Description: mediates post-transcriptional control of comE operon expression
Gene name | comN |
Synonyms | yrzD |
Essential | no |
Product | post-transcriptional regulator of comE expression |
Function | regulation of competence and DNA uptake |
Gene expression levels in SubtiExpress: comN | |
Interactions involving this protein in SubtInteract: ComN | |
MW, pI | 11 kDa, 4.622 |
Gene length, protein length | 294 bp, 98 aa |
Immediate neighbours | secDF, spoVB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
genetic competence, membrane proteins
This gene is a member of the following regulons
The ComN regulon: comEA-comEB-comEC
The gene
Basic information
- Locus tag: BSU27660
Phenotypes of a mutant
Database entries
- BsubCyc: BSU27660
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU27660
- Structure:
- UniProt: O32049
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
- number of protein molecules per cell (minimal medium with glucose and ammonium): 140 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References