Difference between revisions of "Protein kinases and phosphatases"
(Created page with 'These enzymes phosphorylate or dephosphorylate other proteins. ==Protein kinases== ===Protein serine kinases=== * HprK (has also phosphorylase activity) …') |
(→Protein serine kinases) |
||
| (16 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
| − | These enzymes phosphorylate or dephosphorylate other [[phosphoproteins|proteins]]. | + | These enzymes phosphorylate or dephosphorylate other [[phosphoproteins|proteins]]. By definition, they use ATP (or GTP) as the phosphoryl group donor (as opposed to phosphotransferases of the [[PTS|phosphotranferase system]] and the [[phosphorelay]]). |
==Protein kinases== | ==Protein kinases== | ||
| + | ===Protein arginine kinases=== | ||
| + | * [[McsB]] | ||
| + | |||
===Protein serine kinases=== | ===Protein serine kinases=== | ||
* [[HprK]] (has also phosphorylase activity) | * [[HprK]] (has also phosphorylase activity) | ||
| + | * [[CotH]] | ||
* [[PrkC]] | * [[PrkC]] | ||
* [[PrkD]] | * [[PrkD]] | ||
| Line 11: | Line 15: | ||
* [[YabT]] | * [[YabT]] | ||
| − | ===Protein tyrosine kinases=== | + | ===Protein tyrosine kinases (see the [http://bykdb.ibcp.fr/BYKdb/BYKdbHelp Bacterial Protein Tyrosine Kinase Database])=== |
* [[PtkA]] | * [[PtkA]] | ||
* [[EpsB]]: similar to [[PtkA]], but has probably no kinase activity | * [[EpsB]]: similar to [[PtkA]], but has probably no kinase activity | ||
| + | |||
| + | ===Protein kinases of [[two-component systems]]=== | ||
| + | * [[ComP]] | ||
| + | * [[DegS]] | ||
| + | * [[DesK]] | ||
| + | * [[LiaS]] | ||
| + | * [[YdfH]] | ||
| + | * [[YfiJ]] | ||
| + | * [[YhcY]] | ||
| + | * [[YvfT]] | ||
| + | * [[YxjM]] | ||
| + | * [[BceS]] | ||
| + | * [[CssS]] | ||
| + | * [[NatK]] | ||
| + | * [[PhoR]] | ||
| + | * [[ResE]] | ||
| + | * [[WalK]] | ||
| + | * [[YbdK]] | ||
| + | * [[YcbM]] | ||
| + | * [[YclK]] | ||
| + | * [[YkoH]] | ||
| + | * [[YrkO]] | ||
| + | * [[YvcQ]] | ||
| + | * [[YvrG]] | ||
| + | * [[YxdK]] | ||
| + | * [[CheA]] | ||
| + | * [[CitS]] | ||
| + | * [[DctS]] | ||
| + | * [[GlnK]] | ||
| + | * [[MalK]] | ||
| + | * [[LytS]] | ||
| + | * [[YesM]] | ||
| + | * [[YwpD]] | ||
| + | * [[KinA]] | ||
| + | * [[KinB]] | ||
| + | * [[KinC]] | ||
| + | * [[KinD]] | ||
| + | * [[KinE]] | ||
==Protein phosphatases== | ==Protein phosphatases== | ||
| + | ===Protein arginine phosphatases=== | ||
| + | * [[YwlE]] | ||
| + | |||
===Protein serine phosphatases=== | ===Protein serine phosphatases=== | ||
* [[PrpC]] | * [[PrpC]] | ||
| Line 22: | Line 67: | ||
* [[RsbX]] | * [[RsbX]] | ||
* [[SpoIIE]] | * [[SpoIIE]] | ||
| + | |||
===Protein tyrosine phosphatases=== | ===Protein tyrosine phosphatases=== | ||
* [[PtpZ]] | * [[PtpZ]] | ||
* [[YfkJ]] | * [[YfkJ]] | ||
| − | * [[ | + | |
| + | ===Protein aspartate phosphatases controlling the [[phosphorelay]] === | ||
| + | * [[Spo0E]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[YisI]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[YnzD]]: dephosphorylation of [[Spo0A]] | ||
| + | * [[RapA]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapB]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapE]]: dephosphorylation of [[Spo0F]] | ||
| + | * [[RapH]]: dephosphorylation of [[Spo0F]] | ||
| + | |||
| + | =Related Lists= | ||
| + | * [[phosphoproteins]] | ||
| + | * [[protein modification]] | ||
| + | * [[two-component systems]] | ||
| + | |||
| + | =Reviews= | ||
| + | <pubmed> 16209347 21372323 23731382 25625314</pubmed> | ||
Latest revision as of 16:59, 19 May 2016
These enzymes phosphorylate or dephosphorylate other proteins. By definition, they use ATP (or GTP) as the phosphoryl group donor (as opposed to phosphotransferases of the phosphotranferase system and the phosphorelay).
Protein kinases
Protein arginine kinases
Protein serine kinases
Protein tyrosine kinases (see the Bacterial Protein Tyrosine Kinase Database)
Protein kinases of two-component systems
- ComP
- DegS
- DesK
- LiaS
- YdfH
- YfiJ
- YhcY
- YvfT
- YxjM
- BceS
- CssS
- NatK
- PhoR
- ResE
- WalK
- YbdK
- YcbM
- YclK
- YkoH
- YrkO
- YvcQ
- YvrG
- YxdK
- CheA
- CitS
- DctS
- GlnK
- MalK
- LytS
- YesM
- YwpD
- KinA
- KinB
- KinC
- KinD
- KinE
Protein phosphatases
Protein arginine phosphatases
Protein serine phosphatases
Protein tyrosine phosphatases
Protein aspartate phosphatases controlling the phosphorelay
- Spo0E: dephosphorylation of Spo0A
- YisI: dephosphorylation of Spo0A
- YnzD: dephosphorylation of Spo0A
- RapA: dephosphorylation of Spo0F
- RapB: dephosphorylation of Spo0F
- RapE: dephosphorylation of Spo0F
- RapH: dephosphorylation of Spo0F
Related Lists
Reviews
Jonathan Dworkin
Ser/Thr phosphorylation as a regulatory mechanism in bacteria.
Curr Opin Microbiol: 2015, 24;47-52
[PubMed:25625314]
[WorldCat.org]
[DOI]
(I p)
Charlotte Cousin, Abderahmane Derouiche, Lei Shi, Yves Pagot, Sandrine Poncet, Ivan Mijakovic
Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation.
FEMS Microbiol Lett: 2013, 346(1);11-9
[PubMed:23731382]
[WorldCat.org]
[DOI]
(I p)
Sandro F F Pereira, Lindsie Goss, Jonathan Dworkin
Eukaryote-like serine/threonine kinases and phosphatases in bacteria.
Microbiol Mol Biol Rev: 2011, 75(1);192-212
[PubMed:21372323]
[WorldCat.org]
[DOI]
(I p)
Michał Obuchowski
[Serine-threonine protein phosphatases from Bacillus subtilis]. [Serynowo-treoninowe fosfatazy białkowe w Bacillus subtilis.]
Postepy Biochem: 2005, 51(1);95-104
[PubMed:16209347]
[WorldCat.org]
(P p)
