pbuE

pbuE
168

putative hypoxanthine exporter

Locus
BSU_05800
Molecular weight
41.38 kDa
Isoelectric point
8.88
Protein length
388 aaSequenceBlast
Gene length
1167 bpSequenceBlast
Function
nucleotide metabolism
Product
putative hypoxanthine exporter
Essential
no
Synonyms
pbuE, ydhL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
625,125  626,291
RNA
Structure
5E54 (PDB) PubMed
5SWE (PDB) PubMed
The protein
Protein family
major facilitator superfamily (according to UniProt)
DHA1 family (single member, according to UniProt)
Structure
6KKL (PDB) (from E. coli, 25% identity) PubMed
Q797E3 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
pbuE
Description
PubMed
Regulation
induced by hypoxanthine and guanine, PurR-independent PubMed
induced by adenine ([regulon|A-box|]) PubMed
Regulatory mechanism
a-box: RNA switch, adenine-controlled, in a-box
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pbuE

2025-03-10 21:19:19

Jstuelk

102

4ad5cb3bc83bd54de6d82c141a796c9b794bb372

625C3B71A89269D217761F5815439949AB35D4AD

Biological materials
Mutant
MGNA-C187 (ydhL::erm), available at the NBRP B. subtilis, Japan
BKE05800 (pbuE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAACAAACTCCTTTACTT,  downstream forward: _UP4_TCCTTGTAAAAGGAGGATTT
BKK05800 (pbuE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAACAAACTCCTTTACTT,  downstream forward: _UP4_TCCTTGTAAAAGGAGGATTT
References
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Page visits: 6235

Time of last update: 2025-04-15 12:19:41

Author of last update: Jstuelk