rae1

rae1
168

ribosome-associated A site endoribonuclease

Locus
BSU_00970
Molecular weight
19.53 kDa
Isoelectric point
7.28
Protein length
170 aaSequenceBlast
Gene length
513 bpSequenceBlast
Function
ribosome-dependent mRNA decay
Product
A site endoribonuclease
Essential
no
Synonyms
yacP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3688 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
116,025  116,537
The protein
Domains
N-terminal NYN domain PubMed
C-terminal flexible RNA-binding domain PubMed
Structure
5MQ8 (PDB) PubMed
P37574 (AlphaFold)
Expression and Regulation
Operons
Genes
gltX-cysE-cysS-mrnC-yacO-rae1
Description
PubMed
Regulation
expression transiently increases in the forespore PubMed
the T-box RNA is degraded by RNase Y PubMed
Regulatory mechanism
T-box: RNA switch, overlaps a transcription terminator upstream of cysE, in T-box
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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gltX→rae1

2025-04-04 01:30:11

Jstuelk

96

9ab774439b3983729fe5811aeaf44f4bc16c609f

BCC6FA512C81F405B92E34AE44A52F949D245F3D

Biological materials
Mutant
MGNA-B885 (yacP::erm), available at the NBRP B. subtilis, Japan
BKE00970 (rae1::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGGTCTTTATTCTCCCA,  downstream forward: _UP4_TAAGTTGACGCTTTTTTGCC
BKK00970 (rae1::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGGTCTTTATTCTCCCA,  downstream forward: _UP4_TAAGTTGACGCTTTTTTGCC
References
Reviews
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Original Publications
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172652156ABFE72D5BAAC22729CE17CA947538B5

Page visits: 2934

Time of last update: 2025-04-09 06:19:00

Author of last update: Jstuelk