fpbO

fpbO
168

petrobactin (3.4-catecholate siderophore) ABC transporter (permease)

Locus
BSU_03810
Molecular weight
35.32 kDa
Isoelectric point
9.73
Protein length
315 aaSequenceBlast
Gene length
948 bpSequenceBlast
Function
acquisition of iron
Product
petrobactin ABC transporter (permease)
Essential
no
Synonyms
fpbO, yclO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4605 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
433,315 → 434,262
The protein
Catalyzed reaction/ biological activity
uptake of the siderophore petrobactin PubMed
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
FecCD subfamily (according to UniProt)
Structure
P94419 (AlphaFold)
Localization
cell  membrane PubMed
Expression and Regulation
Operons
Genes
fpbN-fpbO-fpbP-fpbQ
Description
PubMed
Regulation
immediately induced upon iron starvation (first wave to allow iron uptake) (Fur) PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
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fpbN→fpbQ

2025-03-16 15:06:23

Jstuelk

106

74ea5c8bb748d23ec3e0cc6fc1179cb8eab26119

67ED5A2606DC68A56E0956D7F4306EC013902C9F

Biological materials
Mutant
MGNA-C066 (yclO::erm), available at the NBRP B. subtilis, Japan
BKE03810 (ΔfpbO::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AACGAGCAAAGCTATTTTCA,  downstream forward: _UP4_TTGCTGTTAAAGGAGAATAA
BKK03810 (ΔfpbO::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AACGAGCAAAGCTATTTTCA,  downstream forward: _UP4_TTGCTGTTAAAGGAGAATAA
References
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Time of last update: 2025-04-08 13:56:31

Author of last update: Jstuelk