Difference between revisions of "PurH"
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphoribosylaminoimidazole carboxamide formyltransferase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphoribosylaminoimidazole carboxamide formyltransferase<br/>and inosine-monophosphate cyclohydrolase |
− | and inosine-monophosphate cyclohydrolase | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || purine biosynthesis |
Revision as of 10:36, 18 June 2009
- Description: phosphoribosylaminoimidazole carboxamide formyltransferase
Gene name | purH |
Synonyms | purJ |
Essential | no |
Product | phosphoribosylaminoimidazole carboxamide formyltransferase and inosine-monophosphate cyclohydrolase |
Function | purine biosynthesis |
MW, pI | 55 kDa, 5.133 |
Gene length, protein length | 1536 bp, 512 aa |
Immediate neighbours | purN, purD |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU06520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (according to Swiss-Prot)
- Protein family: purH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P12048
- KEGG entry: [3]
- E.C. number: 2.1.2.3
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References