GalK

• Description: galactokinase
  
  

Gene name	galK
Synonyms	ipa-35d
Essential	no
Product	galactokinase
Function	galactose utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	43 kDa, 5.148
Gene length, protein length	1170 bp, 390 aa
Immediate neighbours	galT, gtaC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38200

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate (according to Swiss-Prot)

• Protein family: GalK subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P39574

• KEGG entry: [3]

• E.C. number: 2.7.1.6

Expression and regulation

• Operon: galK-galT

• Sigma factor:

• Regulation: repressed by glucose (CcpA)

• Regulatory mechanism: CcpA: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed