Difference between revisions of "ThiE"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU38290 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39594 P39594] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39594 P39594] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU38290] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.5.1.3 2.5.1.3] | * '''E.C. number:''' [http://www.expasy.org/enzyme/2.5.1.3 2.5.1.3] | ||
Revision as of 14:20, 3 June 2009
- Description: thiamine-phosphate diphosphorylase
| Gene name | thiE |
| Synonyms | thiC, ipa-26d, ywbK |
| Essential | no |
| Product | thiamine-phosphate diphosphorylase |
| Function | biosynthesis of thiamine by 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate |
| MW, pI | 23 kDa, 5.058 |
| Gene length, protein length | 666 bp, 222 aa |
| Immediate neighbours | ywbL, thiM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU38290
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)thiazole = diphosphate + thiamine phosphate (according to Swiss-Prot)
- Protein family: TMP-PPase family (according to Swiss-Prot)
- Paralogous protein(s): TenI
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1G6C
- Swiss prot entry: P39594
- KEGG entry: [3]
- E.C. number: 2.5.1.3
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
