Difference between revisions of "AcsA"
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=== Basic information === | === Basic information === | ||
− | * '''Locus tag:''' | + | * '''Locus tag:''' BSU29680 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39062 P39062] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39062 P39062] | ||
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29680] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/6.2.1.1 6.2.1.1] | * '''E.C. number:''' [http://www.expasy.org/enzyme/6.2.1.1 6.2.1.1] |
Revision as of 11:18, 3 June 2009
- Description: acetyl-CoA synthetase
Gene name | acsA |
Synonyms | |
Essential | no |
Product | acetyl-CoA synthetase) |
Function | utilization of acetate, fatty acids |
MW, pI | 64 kDa, 5.547 |
Gene length, protein length | 1716 bp, 572 aa |
Immediate neighbours | tyrS, acuA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU29680
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA (according to Swiss-Prot)
- Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: acetylated on Lys-549 by AcuA, this results in inactivation PubMed, deacetylated by SrtN and AcuC deacetylates (and thereby activates) AcsA PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P39062
- KEGG entry: [3]
- E.C. number: 6.2.1.1
Additional information
Expression and regulation
- Operon: acsA
- Regulatory mechanism: CodY: transcription repression PubMed1 PubMed2, CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed