Difference between revisions of "UxaC"
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 | + | ** repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed2] |
** induced by galacturonate ([[ExuR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed] | ** induced by galacturonate ([[ExuR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 | + | ** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed2] |
| + | |||
** [[ExuR]]: reanscription repression in the absence of inducer [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed] | ** [[ExuR]]: reanscription repression in the absence of inducer [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed] | ||
Revision as of 13:45, 30 May 2009
- Description: glucuronate isomerase (D-glucuronate, D-galacturonate)
| Gene name | uxaC |
| Synonyms | yjmA |
| Essential | no |
| Product | glucuronate isomerase (D-glucuronate, D-galacturonate) |
| Function | hexuronate utilization |
| MW, pI | 54 kDa, 5.174 |
| Gene length, protein length | 1419 bp, 473 aa |
| Immediate neighbours | ndh, yjmB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glucuronate = D-fructuronate (according to Swiss-Prot)
- Protein family: uronate isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: O34808
- KEGG entry: BSU12300
- E.C. number: 5.3.1.12
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Y Miwa, A Nakata, A Ogiwara, M Yamamoto, Y Fujita
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis.
Nucleic Acids Res: 2000, 28(5);1206-10
[PubMed:10666464]
[WorldCat.org]
[DOI]
(I p)
K R Mekjian, E M Bryan, B W Beall, C P Moran
Regulation of hexuronate utilization in Bacillus subtilis.
J Bacteriol: 1999, 181(2);426-33
[PubMed:9882655]
[WorldCat.org]
[DOI]
(P p)
Carlo Rivolta, Blazenka Soldo, Vladimir Lazarevic, Bernard Joris, Catherine Mauël, Dimitri Karamat
A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.
Microbiology (Reading): 1998, 144 ( Pt 4);877-884
[PubMed:9579062]
[WorldCat.org]
[DOI]
(P p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
