Difference between revisions of "PucM"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' 5-hydroxyisourate + H<sub>2</sub>O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate (according to Swiss-Prot)
  
 
* '''Protein family:''' 5-hydroxyisourate hydrolase subfamily (according to Swiss-Prot)
 
* '''Protein family:''' 5-hydroxyisourate hydrolase subfamily (according to Swiss-Prot)

Revision as of 13:43, 24 May 2009

  • Description: uricase

Gene name pucM
Synonyms yunM
Essential no
Product uricase
Function purine utilization
MW, pI 13 kDa, 5.082
Gene length, protein length 363 bp, 121 aa
Immediate neighbours pucL, pucE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucM context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate (according to Swiss-Prot)
  • Protein family: 5-hydroxyisourate hydrolase subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed