Difference between revisions of "FolD"
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' 5,10-methylenetetrahydrofolate + NADP<sup>+</sup> = 5,10-methenyltetrahydrofolate + NADPH (according to Swiss-Prot) |
* '''Protein family:''' tetrahydrofolate dehydrogenase/cyclohydrolase family (according to Swiss-Prot) | * '''Protein family:''' tetrahydrofolate dehydrogenase/cyclohydrolase family (according to Swiss-Prot) |
Revision as of 00:53, 24 May 2009
- Description: methylenetetrahydrofolate dehydrogenase (NADP)
Gene name | folD |
Synonyms | yqiA |
Essential | yes PubMed |
Product | methylenetetrahydrofolate dehydrogenase (NADP) |
Function | formylation of Met-tRNA(fMet) |
MW, pI | 30 kDa, 5.6 |
Gene length, protein length | 849 bp, 283 aa |
Immediate neighbours | yqiB, nusB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH (according to Swiss-Prot)
- Protein family: tetrahydrofolate dehydrogenase/cyclohydrolase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P54382
- KEGG entry: BSU24310
- E.C. number: 1.5.1.5
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed