Difference between revisions of "LutC"

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=References=
 
=References=
  
# Chai Y, Kolter R, Losick R. (2009) A WIDELY CONSERVED GENE CLUSTER REQUIRED FOR LACTATE UTILIZATION IN BACILLUS SUBTILIS AND ITS INVOLVEMENT IN BIOFILM FORMATION. ''J Bacteriol.'' '''Feb 6.''' Epub ahead of print [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed]
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<pubmed> 19201793 </pubmed>
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 18:17, 22 May 2009

  • Description: lactate catabolic enzyme

Gene name lutC
Synonyms yvbY
Essential no
Product unknown
Function utilization of lactate
MW, pI 26 kDa, 5.157
Gene length, protein length 720 bp, 240 aa
Immediate neighbours yvbX, lutB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvbY context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

no growth with lactate as the single carbon source PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate PubMed
  • Protein family: UPF0707 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: induction by lactate PubMed
  • Regulatory mechanism: dual repression by LutR (inducer lactate) and SinR PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed