Difference between revisions of "MreB"
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mreC]]'', ''[[radC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mreC]]'', ''[[radC]]'' | ||
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| − | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14763]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
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|colspan="2" | '''Genetic context''' <br/> [[Image:mreB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mreB_context.gif]] | ||
Revision as of 23:23, 16 April 2009
- Description: cell-shape determining protein
| Gene name | mreB |
| Synonyms | divIVB |
| Essential | yes PubMed |
| Product | cell-shape determining protein |
| Function | cell-shape determination |
| MW, pI | 35 kDa, 4.901 |
| Gene length, protein length | 1011 bp, 337 aa |
| Immediate neighbours | mreC, radC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed, the mutation can be suppressed by inactivation of ponA, ptsI, ccpA PubMed or addition of 5 mM Magnesium to the growth medium PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: forms helical structures close to the inner surface of the cytoplasmic membrane PubMed
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
- Antibody: available in the Jeff Errington and Peter Graumann labs
Labs working on this gene/protein
Jeff Errington, Newcastle University, UK homepage
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
- Carballido-Lopez, R., Formstone, A., Li, Y., Ehrlich, S. D., and Errington, J. (2006) Actin homolog MreBH governs cell morphogenesis by localization of the cell wall hydrolase LytE. Dev. Cell 11: 399-409. PubMed
- Defeu Soufo, H. J., and P. Graumann. 2006. Dynamic localization and interaction with other Bacillus subtilis actin-like proteins are important for the funtion of MreB. Mol. Microbiol. 62: 1340-1356. PubMed
- Kawai, Y., R. A. Daniel, J. Errington (2009) Regulation of cell wall morphogenesis in Bacillus subtilis by recruitment of PBP1 to the MreB helix. Mol. Microbiol. 71: 1131-1144. PubMed
- Mayer JA, Amann KJ. (2009) Assembly properties of the Bacillus subtilis actin, MreB. Cell Motil Cytoskeleton. Feb;66(2): 109-18. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
