Ctc

• Description: general stress protein, similar to L25
  
  

Gene name	ctc
Synonyms
Essential	no
Product	ribosomal protein
Function	unknown
MW, pI	21 kDa, 4.216
Gene length, protein length	612 bp, 204 aa
Immediate neighbours	prs, spoVC
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: binds 5S rRNA PubMed

• Localization: in the ribosome (large subunit) PubMed

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

gcaD-prs-ctc

ctc

• Sigma factor: gcaD: SigA, ctc: SigB

• Regulation: induced under stress conditions

• Regulatory mechanism: alternative sigma factor, SigB

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: available in Stülke lab

References

1. Schmalisch, M., Langbein, I. & Stülke, J. (2002) The general stress protein Ctc of Bacillus subtilis is a ribosomal protein. J. Mol. Microbiol. Biotechnol. 4: 495-501. PubMed
2. Ollington, J. F., Haldenwang, W. G., Huynh, T. V. and Losick, R. 1981. Developmentally regulated transcription in a cloned segment of the Bacillus subtilis chromosome. J. Bacteriol. 147: 432-442. PubMed
3. Truitt, C. L., Weaver, E. A. and Haldenwang, W. G. 1988. Effects on growth and sporulation of inactivation of a Bacillus subtilis gene (ctc) transcribed in vitro by minor vegetative cell RNA polymerases (E-sigma(37), E-sigma(32)). Mol. Gen. Genet. 212: 166-171. PubMed
4. Haldenwang, W. G. & Losick, R. (1979). A modified RNA polymerase transcribes a cloned gene under sporulation control in Bacillus subtilis. Nature 282, 256-260 PubMed
5. Gongadze GM, Korepanov AP, Korobeinikova AV, Garber MB (2008) Bacterial 5S rRNA-binding proteins of the CTC family. Biochemistry (Moscow) 73: 1405-1417. PubMed
6. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed