Difference between revisions of "PerR"
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| − | * '''Description:''' | + | * '''Description:''' transcriptional repressor of the peroxide regulon <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the response to peroxide |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 5.888 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 5.888 | ||
Revision as of 18:27, 18 March 2009
- Description: transcriptional repressor of the peroxide regulon
| Gene name | perR |
| Synonyms | ygaG |
| Essential | no |
| Product | transcriptional repressor |
| Function | regulation of the response to peroxide |
| MW, pI | 16 kDa, 5.888 |
| Gene length, protein length | 435 bp, 145 aa |
| Immediate neighbours | ygaF, ygzB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Genes repressed by PerR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation: negative autoregulation PubMed
- Regulatory mechanism: repressed by PerR PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
- Herbig AF, Helmann JD. (2001) Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA. Mol Microbiol. Aug;41(4): 849-59. PubMed
- Fuangthong M, Herbig AF, Bsat N, Helmann JD. (2002) Regulation of the Bacillus subtilis fur and perR genes by PerR: not all members of the PerR regulon are peroxide inducible. J Bacteriol. Jun;184(12): 3276-86.PubMed
