Difference between revisions of "ClpC"

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(Basic information/ Evolution)
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* '''Description:''' write here <br/><br/>
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* '''Description:''' ATP-dependent Clp protease, ATPase subunit <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
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|-
|style="background:#ABCDEF;" align="center"| '''Product''' || class III stress response-related ATPase
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|style="background:#ABCDEF;" align="center"| '''Product''' || ATP-dependent Clp protease, ATPase subunit
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulator of late competence genes;
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|style="background:#ABCDEF;" align="center"|'''Function''' || protein degradation;
 
positive regulator of autolysin (LytC and LytD) synthesis
 
positive regulator of autolysin (LytC and LytD) synthesis
 
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|-

Revision as of 14:38, 16 March 2009

  • Description: ATP-dependent Clp protease, ATPase subunit

Gene name clpC
Synonyms mecB
Essential no
Product ATP-dependent Clp protease, ATPase subunit
Function protein degradation;

positive regulator of autolysin (LytC and LytD) synthesis

MW, pI 89 kDa, 5.746
Gene length, protein length 2430 bp, 810 aa
Immediate neighbours mcsB, radA
Gene sequence (+200bp) Protein sequence
Genetic context
ClpC context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): ClpE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Kock H, Gerth U, Hecker M. (2004) MurAA, catalysing the first committed step in peptidoglycan biosynthesis, is a target of Clp-dependent proteolysis in Bacillus subtilis. Mol Microbiol, 51:1087-1102. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed