Difference between revisions of "ThiE"

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|style="background:#ABCDEF;" align="center"| '''Product''' || thiamine-phosphate pyrophosphorylase (EC 2.5.1.3)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || thiamine-phosphate pyrophosphorylase (EC 2.5.1.3)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || substitution of the pyrophosphate of 2-methyl-4-amino-5-hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate
+
|style="background:#ABCDEF;" align="center"|'''Function''' || substitution of the pyrophosphate of 2-methyl-4-amino-5-hydroxymethylpyrimidine pyrophosphate  
 +
by 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 5.058   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 5.058   
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* '''Protein family:'''
 
* '''Protein family:'''
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[TenI]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===

Revision as of 19:15, 15 March 2009

  • Description: write here

Gene name thiE
Synonyms thiC, ipa-26d, ywbK
Essential no
Product thiamine-phosphate pyrophosphorylase (EC 2.5.1.3)
Function substitution of the pyrophosphate of 2-methyl-4-amino-5-hydroxymethylpyrimidine pyrophosphate

by 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate

MW, pI 23 kDa, 5.058
Gene length, protein length 666 bp, 222 aa
Immediate neighbours ywbL, thiM
Gene sequence (+200bp) Protein sequence
Genetic context
ThiE context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): TenI

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed