Stusti 2018

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA: Niklas Kehl

David A Hiller, Scott A Strobel
The chemical versatility of RNA.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2929-35
[PubMed:21930584] [WorldCat.org] [DOI] (I p)

RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair: Andrea Lehner

Savio T de Farias, Ariosvaldo P Dos Santos Junior, Thais G Rêgo, Marco V José
Origin and Evolution of RNA-Dependent RNA Polymerase.
Front Genet: 2017, 8;125
[PubMed:28979293] [WorldCat.org] [DOI] (P e)

Thomas A Guilliam, Benjamin A Keen, Nigel C Brissett, Aidan J Doherty
Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes.
Nucleic Acids Res: 2015, 43(14);6651-64
[PubMed:26109351] [WorldCat.org] [DOI] (I p)

Maria L Kireeva, Mikhail Kashlev, Zachary F Burton
RNA polymerase structure, function, regulation, dynamics, fidelity, and roles in gene expression.
Chem Rev: 2013, 113(11);8325-30
[PubMed:24219496] [WorldCat.org] [DOI] (I p)

S Buratowski
The basics of basal transcription by RNA polymerase II.
Cell: 1994, 77(1);1-3
[PubMed:8156586] [WorldCat.org] [DOI] (P p)

Ribozymes (catalytically active RNAs: Christian Thielscher)

Christian Hammann, Andrej Luptak, Jonathan Perreault, Marcos de la Peña
The ubiquitous hammerhead ribozyme.
RNA: 2012, 18(5);871-85
[PubMed:22454536] [WorldCat.org] [DOI] (I p)

Sidney Altman
Ribonuclease P.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2936-41
[PubMed:21930585] [WorldCat.org] [DOI] (I p)

David M J Lilley
Mechanisms of RNA catalysis.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2910-7
[PubMed:21930582] [WorldCat.org] [DOI] (I p)

David M J Lilley
The Varkud satellite ribozyme.
RNA: 2004, 10(2);151-8
[PubMed:14730013] [WorldCat.org] [DOI] (P p)

R Shippy, R Lockner, M Farnsworth, A Hampel
The hairpin ribozyme. Discovery, mechanism, and development for gene therapy.
Mol Biotechnol: 1999, 12(1);117-29
[PubMed:10554775] [WorldCat.org] [DOI] (P p)

K Kruger, P J Grabowski, A J Zaug, J Sands, D E Gottschling, T R Cech
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena.
Cell: 1982, 31(1);147-57
[PubMed:6297745] [WorldCat.org] [DOI] (P p)

Riboregulation and virulence, targeting by antibiotics: Theresia Eisele

Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688] [WorldCat.org] [DOI] (I p)

Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506] [WorldCat.org] [DOI] (P e)

Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876] [WorldCat.org] [DOI] (I p)

Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192] [WorldCat.org] [DOI] (I e)

Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123] [WorldCat.org] [DOI] (I p)

Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414] [WorldCat.org] [DOI] (I p)

John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753] [WorldCat.org] [DOI] (I p)

Riboswitch modeling: Mark Sinzger

Christopher Schneider, Leo Bronstein, Jascha Diemer, Heinz Koeppl, Beatrix Suess
ROC'n'Ribo: Characterizing a Riboswitching Expression System by Modeling Single-Cell Data.
ACS Synth Biol: 2017, 6(7);1211-1224
[PubMed:28591515] [WorldCat.org] [DOI] (I p)

Marco Barsacchi, Eva Maria Novoa, Manolis Kellis, Alessio Bechini
SwiSpot: modeling riboswitches by spotting out switching sequences.
Bioinformatics: 2016, 32(21);3252-3259
[PubMed:27378291] [WorldCat.org] [DOI] (I p)

Chase L Beisel, Christina D Smolke
Design principles for riboswitch function.
PLoS Comput Biol: 2009, 5(4);e1000363
[PubMed:19381267] [WorldCat.org] [DOI] (I p)

The RNA world and evolution: Roman Doll

Ádám Kun, Ádám Radványi
The evolution of the genetic code: Impasses and challenges.
Biosystems: 2018, 164;217-225
[PubMed:29031737] [WorldCat.org] [DOI] (I p)

Thomas Fouqueau, Fabian Blombach, Finn Werner
Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation.
Annu Rev Microbiol: 2017, 71;331-348
[PubMed:28657884] [WorldCat.org] [DOI] (I p)

Abe Pressman, Celia Blanco, Irene A Chen
The RNA World as a Model System to Study the Origin of Life.
Curr Biol: 2015, 25(19);R953-63
[PubMed:26439358] [WorldCat.org] [DOI] (I p)

Jessica C Bowman, Nicholas V Hud, Loren Dean Williams
The ribosome challenge to the RNA world.
J Mol Evol: 2015, 80(3-4);143-61
[PubMed:25739364] [WorldCat.org] [DOI] (I p)

Daniel Lundin, Gustav Berggren, Derek T Logan, Britt-Marie Sjöberg
The origin and evolution of ribonucleotide reduction.
Life (Basel): 2015, 5(1);604-36
[PubMed:25734234] [WorldCat.org] [DOI] (P e)

Paul G Higgs, Niles Lehman
The RNA World: molecular cooperation at the origins of life.
Nat Rev Genet: 2015, 16(1);7-17
[PubMed:25385129] [WorldCat.org] [DOI] (I p)

Markus Ralser
The RNA world and the origin of metabolic enzymes.
Biochem Soc Trans: 2014, 42(4);985-8
[PubMed:25109990] [WorldCat.org] [DOI] (I p)

Eugene V Koonin, Artem S Novozhilov
Origin and evolution of the genetic code: the universal enigma.
IUBMB Life: 2009, 61(2);99-111
[PubMed:19117371] [WorldCat.org] [DOI] (I p)

Yuri I Wolf, Eugene V Koonin
On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization.
Biol Direct: 2007, 2;14
[PubMed:17540026] [WorldCat.org] [DOI] (I e)

RNA modification: Jan Michel Göring

Baixing Wu, Li Li, Ying Huang, Jinbiao Ma, Jinrong Min
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Curr Opin Struct Biol: 2017, 47;67-76
[PubMed:28624569] [WorldCat.org] [DOI] (I p)

Hiroyuki Hori
Transfer RNA methyltransferases with a SpoU-TrmD  (SPOUT) fold and their modified nucleosides in  tRNA.
Biomolecules: 2017, 7(1);
[PubMed:28264529] [WorldCat.org] [DOI] (I e)

Ajay K Rana, Serge Ankri
Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases.
Front Genet: 2016, 7;99
[PubMed:27375676] [WorldCat.org] [DOI] (P e)

Marcus Fislage, Lina Wauters, Wim Versées
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers: 2016, 105(8);568-79
[PubMed:26832457] [WorldCat.org] [DOI] (I p)

Clément Dégut, Luc Ponchon, Marcia Folly-Klan, Pierre Barraud, Carine Tisné
The m1A(58) modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI.
Biophys Chem: 2016, 210;27-34
[PubMed:26189113] [WorldCat.org] [DOI] (I p)

RNA degradation/processing: Lena Kricsfalussy-Hrabar

John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538] [WorldCat.org] [DOI] (I p)

Soraya Aït-Bara, Agamemnon J Carpousis
RNA degradosomes in bacteria and chloroplasts: classification, distribution and evolution of RNase E homologs.
Mol Microbiol: 2015, 97(6);1021-135
[PubMed:26096689] [WorldCat.org] [DOI] (I p)

Jonathan Houseley, David Tollervey
The many pathways of RNA degradation.
Cell: 2009, 136(4);763-76
[PubMed:19239894] [WorldCat.org] [DOI] (I p)

Regulation by non-coding RNA: Maxin Drömer

Yvonne Göpel, Muna A Khan, Boris Görke
Ménage à trois: post-transcriptional control of the key enzyme for cell envelope synthesis by a base-pairing small RNA, an RNase adaptor protein, and a small RNA mimic.
RNA Biol: 2014, 11(5);433-42
[PubMed:24667238] [WorldCat.org] [DOI] (I p)

Boris Görke, Jörg Vogel
Noncoding RNA control of the making and breaking of sugars.
Genes Dev: 2008, 22(21);2914-25
[PubMed:18981470] [WorldCat.org] [DOI] (P p)

CRISPR/Cas: Application and groundbreaking perspectives: Johann Liebeton

Addison V Wright, James K Nuñez, Jennifer A Doudna
Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering.
Cell: 2016, 164(1-2);29-44
[PubMed:26771484] [WorldCat.org] [DOI] (I p)

Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer: Artur Fornol

Tessa E F Quax, Nico J Claassens, Dieter Söll, John van der Oost
Codon Bias as a Means to Fine-Tune Gene Expression.
Mol Cell: 2015, 59(2);149-61
[PubMed:26186290] [WorldCat.org] [DOI] (I p)

Sibah Alkatib, Lars B Scharff, Marcelo Rogalski, Tobias T Fleischmann, Annemarie Matthes, Stefanie Seeger, Mark A Schöttler, Stephanie Ruf, Ralph Bock
The contributions of wobbling and superwobbling to the reading of the genetic code.
PLoS Genet: 2012, 8(11);e1003076
[PubMed:23166520] [WorldCat.org] [DOI] (I p)

Tamir Tuller
Codon bias, tRNA pools and horizontal gene transfer.
Mob Genet Elements: 2011, 1(1);75-77
[PubMed:22016848] [WorldCat.org] [DOI] (P p)

Richard Giegé, Frank Jühling, Joern Pütz, Peter Stadler, Claude Sauter, Catherine Florentz
Structure of transfer RNAs: similarity and variability.
Wiley Interdiscip Rev RNA: 2012, 3(1);37-61
[PubMed:21957054] [WorldCat.org] [DOI] (I p)

Ingo Wohlgemuth, Corinna Pohl, Joerg Mittelstaet, Andrey L Konevega, Marina V Rodnina
Evolutionary optimization of speed and accuracy of decoding on the ribosome.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2979-86
[PubMed:21930591] [WorldCat.org] [DOI] (I p)

Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)

Shahnaz Haque, Lorna W Harries
Circular RNAs (circRNAs) in Health and Disease.
Genes (Basel): 2017, 8(12);
[PubMed:29182528] [WorldCat.org] [DOI] (P e)

Feng Liu
Enhancer-derived RNA: A Primer.
Genomics Proteomics Bioinformatics: 2017, 15(3);196-200
[PubMed:28533025] [WorldCat.org] [DOI] (I p)

Kuei-Yang Hsiao, H Sunny Sun, Shaw-Jenq Tsai
Circular RNA - New member of noncoding RNA with novel functions.
Exp Biol Med (Maywood): 2017, 242(11);1136-1141
[PubMed:28485684] [WorldCat.org] [DOI] (I p)

Yiwen Fang, Melissa J Fullwood
Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer.
Genomics Proteomics Bioinformatics: 2016, 14(1);42-54
[PubMed:26883671] [WorldCat.org] [DOI] (I p)

Tae-Kyung Kim, Martin Hemberg, Jesse M Gray
Enhancer RNAs: a class of long noncoding RNAs synthesized at enhancers.
Cold Spring Harb Perspect Biol: 2015, 7(1);a018622
[PubMed:25561718] [WorldCat.org] [DOI] (I e)

Kevin C Wang, Howard Y Chang
Molecular mechanisms of long noncoding RNAs.
Mol Cell: 2011, 43(6);904-14
[PubMed:21925379] [WorldCat.org] [DOI] (I p)

Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways

Sujin Jeong, Seung Ryul Han, Young Ju Lee, Seong-Wook Lee
Selection of RNA aptamers specific to active prostate-specific antigen.
Biotechnol Lett: 2010, 32(3);379-85
[PubMed:19943183] [WorldCat.org] [DOI] (I p)

Regina Stoltenburg, Christine Reinemann, Beate Strehlitz
SELEX--a (r)evolutionary method to generate high-affinity nucleic acid ligands.
Biomol Eng: 2007, 24(4);381-403
[PubMed:17627883] [WorldCat.org] [DOI] (P p)

The mysterious function and role of 6S-RNA and pRNA in bacteria

Benedikt Steuten, Philipp G Hoch, Katrin Damm, Sabine Schneider, Karen Köhler, Rolf Wagner, Roland K Hartmann
Regulation of transcription by 6S RNAs: insights from the Escherichia coli and Bacillus subtilis model systems.
RNA Biol: 2014, 11(5);508-21
[PubMed:24786589] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Karen M Wassarman
6S RNA, a global regulator of transcription in Escherichia coli, Bacillus subtilis, and beyond.
Annu Rev Microbiol: 2014, 68;45-60
[PubMed:24742053] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Karen M Wassarman
6S-1 RNA function leads to a delay in sporulation in Bacillus subtilis.
J Bacteriol: 2013, 195(9);2079-86
[PubMed:23457253] [WorldCat.org] [DOI] (I p)

Karen M Wassarman
6S RNA: a small RNA regulator of transcription.
Curr Opin Microbiol: 2007, 10(2);164-8
[PubMed:17383220] [WorldCat.org] [DOI] (P p)