|
|
| Line 1: |
Line 1: |
| | | | |
| − | = Sunday June 11, 2017 = | + | = Tuesday 12th June = |
| | | | |
| − | * 14:00 - 15:00 Registration | + | * 8:30 – 8:55 Registration |
| − | * 14:45 - 15:00 – Welcome remarks, [[Jörg Stülke]] | + | * 8:55 Welcome - Chancellors’ Building, room 1.12 |
| | | | |
| − | == Session 1 [[Sporulation]]== | + | == Session 1 Regulation== |
| − | CHAIR: [[Sigal Ben-Yehuda]] | + | CHAIR: David Leak |
| − | * 15:00 - 15:25 [[Richard Losick]] | + | * 09:00 [[Ciaran Condon]] |
| − | **Stochasticity and cell-fate determination during [[sporulation]] in ''B. subtilis'' | + | ** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]] |
| − | * 15:30 - 15:40 Alper Mutlu | + | * 09:15 [[Roland Hartmann]] |
| − | ** Phenotypic memory links entry and exit from dormancy by a spore quantity-quality tradeoff in ''Bacillus subtilis'' | + | ** Function and regulation of two 6S RNAs in Bacillus subtilis |
| − | * 15:45 - 15:55 [[Patrick Eichenberger]] | + | * 09:30 [[Matthias Mack]] |
| − | ** Inferring the ''Bacillus subtilis'' global gene regulation network | + | ** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis'' |
| − | * 16:00 - 16:10 [[Tony Wilkinson]] | + | * 09:45 Hermann Rath |
| − | ** Structures of [[SpoIIE]] reveal a regulatory switch shared across the PPC2 phosphatase family and extending to the proteasomal proteases | + | ** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis'' |
| − | * 16:15 - 16:25 David Roberts
| + | * 10:00 Laura Teichmann |
| − | ** Polar segregation of the chromosome origins during [[sporulation]] in ''Bacillus subtilis''
| + | ** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]] |
| − | * 16:30 - 16:40 Anna Grela | + | * 10:15 Sylvain Durand |
| − | ** Functional analysis of [[GerAA]] subunit of ''Bacillus subtilis'' GerA [[germination]] receptor | + | ** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation |
| − | * 16:45 - 16:55 Eammon Riley | |
| − | ** Defining the metabolic landscape of the ''Bacillus subtilis'' sporangium | |
| | | | |
| − | == 17:00 Welcome reception== | + | == 10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer== |
| | | | |
| − | = Monday June 12, 2017 = | + | == Session 2 [[Cell division]]== |
| | + | CHAIR: TBA |
| | + | * 11:00 [[Henrik Strahl]] |
| | + | ** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains |
| | + | * 11:15 Jeanine Rismondo |
| | + | ** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation |
| | + | * 11:30 Edward de Koning |
| | + | ** [[Divisome]] maturation in ''Bacillus subtilis'' single cells |
| | + | * 11:45 Seamus Holden |
| | + | ** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]] |
| | + | * 12:00 [[Dirk-Jan Scheffers]] |
| | + | ** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]] |
| | + | * 12:15 Yongqiang Gao |
| | + | ** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii'' |
| | | | |
| − | == Session 2 Cell biology 1 ==
| |
| − | CHAIR: [[Dirk-Jan Scheffers]]
| |
| − | * 08:30 - 08:55 [[Jan Willem Veening]]
| |
| − | ** Identification of a unique cell cycle regulator in ''Streptococcus pneumoniae'' by en masse GFP localization and CRISPRi phenotyping
| |
| − | * 09:00 - 09:10 [[Kumaran Ramamurthi]]
| |
| − | ** An essential ''Staphylococcus aureus'' [[cell division]] protein regulates both [[FtsZ]] assembly and disassembly
| |
| − | * 09:15 - 09:25 Elhanan Tzipilevich
| |
| − | ** Acquisition of phage sensitivity by bacteria through exchange of phage receptors
| |
| − | * 09:30 - 09:40 Lauren Cowley
| |
| − | ** Evidence for different rates in the mechanisms of recombination in pneumoccal biofilms
| |
| − | * 09:45 - 09:55 Nada Labajova
| |
| − | ** Clostridial Min system – possible mechanism of functioning during [[cell division]] and [[sporulation]]
| |
| − | * 10:00 - 10:10 Kenneth Seistrup
| |
| − | ** Lysis induced by membrane depolarisation is caused by [[MreB]]-linked mis-regulation of key autolysins in ''Bacillus subtilis''
| |
| | | | |
| − | * 10:15 - 10:45 Coffee break
| + | == 12:30 – 14:30 Lunch and Poster Session 1== |
| − | == Session 3 Biotechnology == | |
| − | CHAIR: [[Oscar Kuipers]]
| |
| − | * 10:45 - 11:10 [[Daniel Lopez]]
| |
| − | ** Lipid rafts: From structural and functional characterization to biotechnological application
| |
| − | * 11:15 - 11:25 Marcus Price
| |
| − | ** CRISPR-Cas9 mediated engineering of industrially relevant ''Bacillus subtilis'' strains
| |
| − | * 11:30 - 11:40 Rocio Aguilar Suarez
| |
| − | ** Less is more: towards development of a genome-reduced ''Bacillus'' as cell factory for vaccine production
| |
| − | * 11:45 - 11:55 Marta Irla
| |
| − | ** Methanol-based production γ-aminobutyric acid in ''B. methanolicus'' MGA3
| |
| − | * 12:00 - 12:10 Rita Cruz
| |
| − | ** A comparative study of native and heterologous enzyme production in ''Bacillus subtilis''
| |
| | | | |
| − | * 12:30 - 14:00 Lunch
| + | == Session 3 – Interesting Biology == |
| − | | + | CHAIR: [[Colin Harwood]] |
| − | == Session 4 New technologies, Systems & Synthetic Biology == | + | * 14:30 [[Jörg Stülke]] |
| − | CHAIR: [[Fabian Commichau]] | + | ** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors |
| − | * 14:00 - 14:25 Carol Gross
| + | * 14:45 Hannah Gaimster |
| − | ** High throughput phenotyping in ''Bacillus subtilis''
| + | ** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis'' |
| − | * 14:30 - 14:40 Christopher Zschiedrich | + | * 15:00 Alexandre Deloupy |
| − | ** Large scale identification of evolutionary mechanism that facilitate protein-protein [[interactions]]
| + | ** Stochastic gene expression in Bacillus subtilis |
| − | * 14:45 - 14:55 [[Leendert Hamoen]]
| + | * 15:15 Sabine Schneider |
| − | ** Construction of a minimal [[divisome]] reveals robustness of [[cell division]] | + | ** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening |
| − | * 15:00 - 15:10 Etienne Dervyn
| + | * 15:30 [[Ken-ichi Yoshida]] |
| − | ** Tailoring ''Bacillus subtilis''-derived chassis for biotechnology applications
| + | ** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer |
| − | * 15:15 - 15:25 Jan Martinussen
| + | * 15:45 Anna A. Toymentseva |
| − | ** Abrupt glucose depletion in ''Lactococcus lactis'' is resulting in an immediate translational stop due to an extreme depletion of the GTP pool
| + | ** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element |
| − | * 15:30 - 15:40 Eugen Peifer
| |
| − | ** Adaptive laboratory evolution of ''Corynebacterium glutamicum'' towards higher growth rates on glucose minimal medium
| |
| − |
| |
| − | * 15:45 - 16:15 Coffee break | |
| − | == Session 5 Cell Biology 2==
| |
| − | CHAIR: [[Stephane Aymerich]]
| |
| − | * 16:15 - 16:25 [[Sven Halbedel]]
| |
| − | ** Peptidoglycan N-deacetylation is jointly controlled by [[PgdA]], PBP A1 and [[GpsB]] in ''Listeria monocytogenes'' | |
| − | * 16:30 - 16:40 [[Rick Lewis]]
| |
| − | ** Exploring the relationship between [[penicillin binding proteins]] and the cell cycle regulator, [[GpsB]]
| |
| − | * 16:45 - 16:55 [[Peter Graumann]]
| |
| − | ** ''B. subtilis'' chromosomes are segregated in in a directed diffusion-like manner, likely based on entropic forces, and are condensed by several SMC condensation centres per cell half, as revealed through single molecule tracking
| |
| − | * 17:00 - 17:10 Koichi Yano
| |
| − | ** ''cis''-acting rDNA act as a loading site for [[Smc]]-[[ScpA]]-[[ScpB]] during nucleoid separation in ''Bacillus subtilis''
| |
| − | * 17:15 - 17:25 [[Marc Bramkamp]] | |
| − | ** A dynamin-like protein involved in bacterial cell membrane surveillance under environmental stress
| |
| − | | |
| − | == Poster Session 1 ==
| |
| − | * 17:30 - 19:30
| |
| − | | |
| − | = Tuesday June 13, 2017 =
| |
| − | == Session 6 Signal transduction ==
| |
| − | CHAIR: [[Ivan Mijakovic]]
| |
| − | * 08:30 - 08:40 Jörgen Johansson
| |
| − | ** Structural and genetic basis for activation and repression of the virulence activator PrfA in ''Listeria monocytogenes''
| |
| − | * 08:45 - 08:55 [[Nathalie Declerck]]
| |
| − | ** Monitoring transcriptional adaptation in live ''Bacillus subtilis'' cells using two-photon fluorescence fluctuation microscopy
| |
| − | * 09:00 - 09:10 Jan Gundlach
| |
| − | ** Cyclic di-AMP controls potassium homeostasis in ''Bacillus subtilis'' | |
| − | * 09:15 - 09:25 [[Sylvie Nessler]] | |
| − | ** Structural insights into streptococcal competence regulation by the cell-to-cell communication system ComRS
| |
| − | * 09:30 - 09:40 Johann Mignolet
| |
| − | ** Ubiquitous rewiring of transcriptional control in streptococci: lesson from competence and predation coupling in ''Streptococcus salivarius'' | |
| − | * 09:45 - 09:55 [[Craig Ellermeier]]
| |
| − | ** [[RsiV]] is a bacterial receptor for lysozyme
| |
| − | * 10:00 - 10:10 Christopher Rao
| |
| − | ** DNA sensing in ''Bacillus subtilis''
| |
| − | | |
| − | *10:15 - 10:45 Coffee break
| |
| − | == Session 7 RNA Biology ==
| |
| − | CHAIR: [[Christiane Wolz]]
| |
| − | * 10:45 - 11:10 Pascale Romby
| |
| − | ** Several regulatory RNAs in ''Staphylococcus aureus ''link stress responses, metabolism and virulence factor synthesis
| |
| − | * 11:15 - 11:25 Ruben Atilho
| |
| − | ** A widespread [[riboswitch]] class regulates guanidine metabolism in bacteria
| |
| − | * 11:30 - 11:40 [[Emma Denham]]
| |
| − | ** Towards the ''in vivo'' RNA interactome of the Gram positive model organism ''Bacillus subtilis''
| |
| − | * 11:45 - 11:55 [[Libor Krasny]]
| |
| − | ** The torpedo effect in [[Bacillus subtilis]]: RNase J1 resolves stalled [[transcription]] complexes
| |
| − | * 12:00 - 12:10 [[Ciaran Condon]]
| |
| − | ** Rae1/[[YacP]], a new endoribonuclease involved in [[ribosome]]-dependent mRNA decay in ''B. subtilis''
| |
| − |
| |
| − | *12:30 - 14:00 Lunch
| |
| − | == Session 8 Metabolism ==
| |
| − | CHAIR: [[Lars Hederstedt]]
| |
| − | * 14:00 - 14:10 Miriam Dormeyer
| |
| − | ** A devil in disguise: a metabolic enzyme converts a transcriptional activator into a repressor
| |
| − | * 14:15 - 14:25 Lianet Noda-Garcia
| |
| − | ** Mapping of chance and necessity in protein sequence evolution in complex bacterial environments
| |
| − | * 14:30 - 14:40 [[Georg Fritz]]
| |
| − | ** Making and breaking the wall – a systems approach to cell wall homeostasis in ''Bacillus subtilis''
| |
| − | * 14:45 - 14:55 [[Christoph Mayer]]
| |
| − | ** Peptidoglycan recycling in Gram-positive bacteria is crucial for survival
| |
| − | * 15:00 - 15:10 Amy Bottomley
| |
| − | ** We are what we eat: Identifying a regulatory crosstalk between central carbon metabolism and [[cell division]] in bacteria
| |
| − | * 15:15 - 15:25 Ines Grilo
| |
| − | ** Glucosaminidase-DNA interaction affects the peptidoglycan hydrolytic activity of glucosaminidase
| |
| − | * 15:30 - 15:40 Daisuke Seo | |
| − | ** Purification and characterization of ferredoxin-NADPH oxidoreductase paralogue [[YcgT]] in gram-positive bacterium ''Bacillus subtilis''
| |
| − |
| |
| − | * 15:45 - 16:15 Coffee break
| |
| − | | |
| − | == Session 9 Lifestyles I - Stress ==
| |
| − | CHAIR: [[Susanne Gebhard]]
| |
| − | * 16:15 - 16:40 [[Jade Wang]]
| |
| − | ** Regulation of stress response and homeostasis by (p)ppGpp in ''Bacillus subtilis'' | |
| − | * 16:45 - 16:55 [[Gerd Bange]]
| |
| − | ** Structural and functional insights into the (p)ppGpp response of ''B. subtilis''
| |
| − | * 17:00 - 17:10 Jose A. Lemos
| |
| − | ** The association of metal homeostasis and (p)ppGpp regulation in the pathophysiology of ''Enterococcus faecalis''
| |
| − | * 17:15 - 17:25 Alexander Reder
| |
| − | ** New insights into the general stress response of ''Bacillus subtilis'' - the [[SigB]] modulon
| |
| − | | |
| − | == Poster Session 2 ==
| |
| − | * 17:30 - 19:30
| |
| − | | |
| − | = Wednesday June 14, 2017 =
| |
| − | == Session 10 Lifestyles II - Biofilm==
| |
| − | CHAIR: [[Ilka Bischofs]]
| |
| − | * 08:30 - 08:40 Polonca Stefanic
| |
| − | ** Kin discrimination foretells ''B. subtilis'' lifestyles
| |
| − | * 08:45 - 08:55 Nozomu Obana
| |
| − | ** Heterogeneity and biofilm morphology in ''Clostridium perfringens''
| |
| − | * 09:00 - 09:10 Sofia Arnaouteli
| |
| − | ** Bifunctionality of a biofilm matrix protein controlled by redox state
| |
| − | * 09:15 - 09:25 Anna Dragos
| |
| − | ** Collapse of genetic division of labor and evolution of autonomy in pellicle biofilms
| |
| − | * 09:30 - 09:40 Tamara Hoffmann
| |
| − | ** Small but essential: the activator protein [[RemA]] links [[biofilm formation]] and osmostress responses in ''Bacillus subtilis''
| |
| − | * 09:45 - 09:55 [[Harald Putzer]]
| |
| − | ** Swarmer cells lead, multiply and generate a trail of quiescent descendants
| |
| − | * 10:00 - 10:10 Pascale Beauregard
| |
| − | ** Biofilm and bacillibactin are essential to iron homeostasis in ''Bacillus subtilis''
| |
| − | | |
| − | * 10:15 - 10:45 Coffee break
| |
| − | | |
| − | == Session 11 DNA replication and recombination/ Interactions with other organisms==
| |
| − | CHAIR: [[xxx]]
| |
| − | * 10:45 - 10:55 Mary Anderson
| |
| − | ** Suppression of [[DNA replication]] overinitiation through lowered levels of the replicative helicase, [[DnaC]]
| |
| − | * 11:00 - 11:10 [[Juan Alonso]]
| |
| − | ** ''Bacillus subtilis'' [[MutS]] modulates non-polar recombination between divergent DNA sequences | |
| − | * 11:15 - 11:25 Paul Straight
| |
| − | ** Antibiotic stimulation of a ''Bacillus subtilis'' motile response
| |
| − | * 11:30 - 11:40 Audrey Labarde
| |
| − | ** Remodelling of the ''Bacillus subtilis'' cytoplasm spatial organization for efficient bacteriophage SPP1 multiplication
| |
| − | * 11:45 - 11:55 [[Elisabeth Grohmann]]
| |
| − | ** Molecular insights in conjugative resistance transfer among Gram-positive pathogens
| |
| − | * 12:00 - 12:10 Javier Pizarro-Cerda
| |
| − | ** A bacteriocin from epidemic ''Listeria'' strains alters the host intestinal microbiota to favor infection
| |
| − | | |
| − | * 12:30 - 14:00 Lunch
| |
| − | | |
| − | == Session 12 The ''Bacillus cereus'' group==
| |
| − | CHAIR: [[Theresa Koehler]]
| |
| − | * 14:00 - 14:25 Didier Lereclus
| |
| − | ** High throughput phenotyping in Bacillus subtilis
| |
| − | * 14:30 - 14:40 Naomi Bier The Influence of the PEP-PTS on Virulence Gene Expression in Bacillus anthracis | |
| − | * 14:45 - 14:55 Sandrine Poncet Hanks-kinases dependent phosphorylation of Bacillus cereus global gene regulator CodY deeply impacts physiology and virulence | |
| − | * 15:00 - 15:10 Monika Ehling-Schulz Food Bacteria Interplay: Concerted action of extrinsic and extrinsic factors gearing toxin synthesis in emetic Bacillus cereus
| |
| − | * 15:15 - 15:25 Joaquin Caro-Astorga Analysis of the molecular machinery implicated in multicellularity in Bacillus cereus
| |
| − | * 15:30 - 15:40 David Sychantha Structural and mechanistic basis for the O-acetylation of secondary cell wall polysaccharide required for the proper assembly of cell walls in the Bacillus cereus group of human pathogens
| |
| − | | |
| − | * 15:45 - 16:15 Coffee break
| |
| − | Session Pathogenicity/ fighting infection
| |
| − | 16:15 - 16:25 Tarek Msadek Bacteriophage mobility and pathogenesis in Staphylococcus aureus
| |
| − | 16:30 - 16:40 Van Loi Vu Real-time imaging of the bacillithiol redox potential in the human pathogen Staphylococcus aureus using a genetically encoded bacilliredoxin-fused redox biosensor
| |
| − | 16:45 - 16:55 Laty Cahoon A structural comparison of Listeria monocytogenes secretion chaperones PrsA1 and PrsA2 reveals molecular features required for virulence
| |
| − | 17:00 - 17:10 Leanne Hays Biofilm formation by the staphylococcal protein SdrC: molecular mechanism and the identification of novel inhibitors
| |
| − | 17:15 - 17:25 Emanuel Hanski Integration of host and bacterial signals controls group A streptococcal bacteriocins production to establish dominance in the fascial niche
| |
| − | Conference dinner
| |
| − | 19:00 - 23:00
| |
| − | | |
| − | = Thursday June 15, 2017 =
| |
| − | | |
| − | Session Lifestyles III
| |
| − | 08:30 - 08:40 Sabine Brantl Type I toxin-antitoxin systems from Bacillus subtilis
| |
| − | 08:45 - 08:55 Michael Prunty Distinct PhoPR-mediated responses to phosphate limitation in Bacillus subtilis subspecies subtilis and spizizenii stem from differences in their anionic polymer composition and metabolism
| |
| − | 09:00 - 09:10 Kursad Turgay Curbing protein synthesis is important for the concerted heat shock response of Bacillus subtilis
| |
| − | 09:15 - 09:25 Thorsten Mascher Three's Company: Cannibalism Toxins and the Corresponding Envelope Stress Responses in Bacillus subtilis
| |
| − | 09:30 - 09:40 Daniel Rojas Induction of the Spx regulon under cell wall stress requires both an ECF sigma factor and an anti-adaptor protein
| |
| − | 09:45 - 09:55 Brandon Anjuwon-Foster The DNA recombinase RecV mediates phase variation of Clostridium difficile flagellum and toxin production
| |
| − | 10:00 - 10:10 Ard Jan Grimbergen Bet-hedging strategies in Bacillus subtilis
| |
| − | 10:15 - 10:45 Coffee break
| |
| − | Session Organizers' favorites
| |
| − | 10:45 - 11:10 Emanuelle Charpentier CRISPR-Cas9: a bacterial immune system repurposed as a transformative genome engineering technology
| |
| − |
| |
| − | 11:15 - 11:25 Ken-Ichi Yoshida Geobacillus kaustophilus Crh is independent of glucose catabolite repression but represses inositol catabolic genes
| |
| − | 11:30 - 11:40 Patricia Dos Santos Mutual specificity of cysteine desulfurases and sulfur acceptors in Bacillus subtilis
| |
| − | * 11:45 - 11:55 Richard Daniel D-ala metabolism in Bacillus subtilis
| |
| − | * 12:00 - 12:10 Anne-Brit Kolsto The putative drug efflux systems of the Bacillus cereus group
| |
| − | 12:30 - 14:00 Lunch
| |
| | | | |
| | + | ==16:00 – 16:30 Tea and Coffee == |
| | + | |
| | + | ==Session 4 – Antibiotics 1 == |
| | + | CHAIR: [[Ulrike Mäder]] |
| | + | * 16:30 Carolin Kobras |
| | + | ** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis'' |
| | + | * 16:45 Luiza P. Morawska |
| | + | ** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance |
| | + | * 17:00 Mary K. Phillips-Jones |
| | + | ** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions |
| | + | * 17:15 Gabriela Henriques |
| | + | ** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis. |
| | | | |
| − | = Monday June 22, 2015 = | + | == Free evening in Bath == |
| | | | |
| − | * 8:15 - 8:30 – Welcome remarks, [[Jim Hoch]], [[Marta Perego]]
| + | = Wednesday 13th June = |
| − | * 8:30 - 9:15 - Keynote lecture: Andrew Camilli, Boston, USA
| |
| − | ** The ''Streptococcus pneumoniae'' cell wall controls pneumolysin release and contributes to virulence.
| |
| − | == Session I Signal transduction I== | |
| − | CHAIR: [[Marta Perego]]
| |
| − | * 9:15 - 9:30 – [[Kevin Devine]], Dublin, Ireland
| |
| − | ** The activities of the [[WalR]]-[[WalK]] and [[PhoP]]-[[PhoR]] [[two-component systems|two-component signal transduction systems]] are determined by signals that emanate from cell wall metabolism in ''Bacillus subtilis''
| |
| − | * 9:30 - 9:45 – [[Hendrik Szurmant]], La Jolla. USA
| |
| − | ** The [[YycF]]-[[YycG]] [[two-component systems|two-component system]] as a regulatory feedback loop for the expression of autolysin activity and the target of antimicrobial activities by human chemokines.
| |
| − | * 9:45 - 10:00 – [[Tarek Msadek]], Paris, France
| |
| − | ** Peptide antibiotic resistance and intramembrane kinase signaling in ''Staphylococcus aureus''.
| |
| | | | |
| − | * 10:00 – 10:30 – COFFEE BREAK | + | == Session 5 Biotechnology == |
| | + | CHAIR: Anne Breüner |
| | + | * 9:00 Andreas Knapp |
| | + | ** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis'' |
| | + | * 9:15 Alexandria Holland |
| | + | ** Investigating protein secretion in ''Geobacillus thermoglucosidasius'' |
| | + | * 9:30 Matthew Styles |
| | + | ** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology |
| | + | * 9:45 Luca Longanesi |
| | + | ** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains |
| | + | * 10:00 Matteo Cavaletti |
| | + | ** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies |
| | + | * 10:15 Ioannis Mougiakos |
| | + | ** Characterizing a thermostable Cas9 for bacterial genome editing and silencing |
| | | | |
| − | == Session II Signal transduction II == | + | == 10:15 - 10:45 Tea and Coffee == |
| − | CHAIR: [[Kevin Devine]]
| |
| − | * 10:30 - 10:45 – Mary K. Phillips-Jones, Preston, UK
| |
| − | ** Characterization of ligand binding by VanS, the membrane sensor kinase of the [[two-component systems|two-component system]] regulating A-type vancomycin resistance in the enterococci.
| |
| − | * 10:45 - 11:00 – Emanuel Hanski, Jerusalem, Israel
| |
| − | ** Regulation of group A ''Streptococcus'' virulence by sensing of asparagines.
| |
| − | * 11:00 - 11:15 – Nicola Horstmann, Houston, USA
| |
| − | ** Regulation of dual-site phosphorylation of response regulator CovR and its impact on group A streptococcus global gene expression and virulence.
| |
| − | * 11:15 - 11:30 – Andrew Ulijasz, London, UK
| |
| − | ** A novel family of [[two-component systems|two-component like]] redox sensors in the Streptococci.
| |
| − | * 11:30 - 11:45 – [[Marta Perego]], La Jolla, USA
| |
| − | ** Media-dependent regulation of ''Bacillus anthracis'' toxin gene expression by the [[ResD]]-[[ResE]]-controlled respiration pathway.
| |
| − | * 11:45 - 12:00 – Maria Cecilia Manilla, Rosario, Argentina
| |
| − | ** Proline residues of [[DesK]] as transmitting elements of cold stimulus.
| |
| − | * 12:00 - 12:15 – [[Ken-ichi Yoshida]], Kobe, Japan
| |
| − | ** Hyperphosphorylation of [[DegU]] interferes with [[CcpA]]-dependent catabolite repression of ''[[rocG]]'' in ''Bacillus subtilis''.
| |
| | | | |
| − | * 12:30 – 14:00 LUNCH
| + | == Session 6 - [[Sporulation]] and development == |
| − | == Parallel sessions ==
| + | CHAIR: TBC |
| − | === Session IIIA Industrial Research (Sala A)===
| + | * 10:45 [[Imrich Barák]] |
| − | CHAIR: Ghislain Schyns | + | ** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis'' |
| − | * 14:00 - 14:45 – Keynote lecture: Sven Panke, Zürich, Switzerland | + | * 11:00 Munehiro Asally |
| − | ** tba
| + | ** Quality monitoring during [[sporulation]] in ''B. subtilis'' |
| − | * 14:45 - 15:00 – Abderahmane Derouiche, Gothenburg, Sweden
| + | * 11:15 [[Ilka Bischofs]] |
| − | ** ''Bacillus subtilis'' [[SalA]] is a phosphorylation-dependent transcription factor that regulates the production of the exoprotease [[AprE]].
| + | ** Phenotypic memory links different stages of the ''B. subtilis'' life cycle |
| − | * 15:00 - 15:15 –Jolanda Neef, Groningen, Netherlands | + | * 11:30 [[Akos Kovacs]] |
| − | ** A novel expression platform for the production of cell wall-bound and secreted staphylococcal antigens. | + | ** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms |
| − | * 15:15 - 15:30 – Ferro Iolanda, Potsdam, Germany
| + | * 11:45 [[Sven Halbedel]] |
| − | ** tRNA abundance and aminoacylation in ''Bacillus licheniformis''.
| + | ** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division'' |
| − | * 15:30 - 15:45 –Birgit Voigt, Greifswald, Germany
| + | * 12:00 Sofia Arnaouteli |
| − | ** The response of ''Bacillus pumilus'' to hydrogen peroxide-provoked oxidative stress.
| + | ** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]] |
| − | | + | * 12:15 Karin Bjerre |
| − | === Session IIIB Host-Pathogen Interaction (Sala B)===
| + | ** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs |
| − | CHAIR: Claire Poyart
| |
| − | * 14:00 - 14:15 – Nancy Freitag, Chicago, USA | |
| − | ** Establishing a new niche for bacterial replication: the surface invasin InlB confers cardiotropism to subpopulations of ''Listeria monocytogenes''. | |
| − | * 14:15 - 14:30 – B. S. Hisey, Bozeman, Montana, USA
| |
| − | ** Role of SaeR/S in secondary ''Staphylococcus aureus'' pneumonia.
| |
| − | * 14:30 - 14:45 – Anthony Richardson, Chapel Hill, NC, USA
| |
| − | ** PPAR-γ is central to the effective host response to ''Staphylococcus aureus'' skin and soft tissue infections.
| |
| − | * 14:45 - 15:00 – A.P.A. Hendrickx, Utrecht, Netherlands | |
| − | ** Antibiotics-driven dysbiosis mediate alternative segregation of ''Enterococcus faecium'' from the intestinal epithelium. | |
| − | * 15:00 - 15:15 –Mariana Martins, Paris, France
| |
| − | ** ''Streptococcus gallolyticus'' Pil3 pilus is required for adhesion to colonic mucus and for colonization of mouse distal colon.
| |
| − | * 15:15 - 15:30 – Salai Madhumathi Parkunan, Oklahoma City, USA
| |
| − | ** ''Bacillus'' intraocular infection: Divergent roles of IL6 and CXCL1.
| |
| − | * 15:30 - 15:45 – Michelle C. Callegan, Oklahoma City, USA | |
| − | ** The role of pili in ''Bacillus cereus'' intraocular infection. | |
| − | | |
| − | * 15:45 - 16:15 - COFFEE BREAK
| |
| − | | |
| − | == Session IV: Vaccines ==
| |
| − | CHAIR: Guido Grandi
| |
| − | * 16:15 - 16:30 – Fabio Bagnoi, Siena, Italy
| |
| − | ** Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against ''Staphylococcus aureus''.
| |
| − | * 16:30 - 16:45 – Olaf Schneewind, Chicago, USA
| |
| − | ** Protein A suppresses immune responses during ''Staphylococcus aureus'' bloodstream infection in guinea pigs.
| |
| − | * 16:45 - 17:00 – Johannes Hübner, Munich, Germany
| |
| − | ** Towards a vaccine against enterococci: Reverse vaccinology and beyond.
| |
| − | * 17:00 - 17:15– Edmondo Campisi, Siena, Italy
| |
| − | ** Structural and genetic characterization of the Type IX Group B ''Streptococcus'' capsular polysaccharide and its relationship with types V and VII
| |
| − | * 17:15 - 17:30 – Joseph J. Zeppa, London, Ontario, Canada
| |
| − | ** Vaccine approaches targeting colonization by ''Streptococcus pyogenes''.
| |
| − | | |
| − | == 17.30 - 19.30 Poster Session I==
| |
| − | | |
| − | = Tuesday June 23, 2015 =
| |
| − | | |
| − | == Parallel sessions ==
| |
| − | === Session VA [[Sporulation]] (Sala A)===
| |
| − | CHAIR: [[Colin Harwood]]
| |
| − | * 8:30 - 8:45 – [[Charles Moran]], Atlanta, USA | |
| − | ** Dual-specificity anti-[[sigma factor]] reinforces control of cell-type specific gene expression in ''Bacillus subtilis''. | |
| − | * 8:45 - 9:00 – Adriano Henriques, Oeiras, Portugal | |
| − | ** Single cell analysis of the pathogenicity locus unravels the relationship between toxin production and spore formation in ''Costridium difficile''. | |
| − | * 9:00 - 9:15 – Adrianne Edwards, Atlanta, USA
| |
| − | ** A putative transcription factor containing conserved tetratricopeptide repeat domains controls [[sporulation]], motility and toxin production in ''Clostridium difficile''.
| |
| − | * 9:15 - 9:30 – James R. Walker, Austin, USA | |
| − | ** Genomics of ''Clostridium taeniosporum'', an organism which forms spores with a bundle of ribbon-like appendages. | |
| − | * 9:30 - 9:45 – [[Leendert Hamoen]], Amsterdam, Netherlands
| |
| − | ** Deep starvation reveals a surprisingly active ''Bacillus subtilis'' growth state.
| |
| − | * 9:45 - 10:00 – Didier Lereclus, Joyu-en-Josas, France
| |
| − | ** Division of labour and terminal differentiation in ''Bacillus thuringiensis''.
| |
| − | * 10:00 - 10:15 – Nils Widderich, Marburg, Germany
| |
| − | ** Dysfunctional [[SigH]] prevents entry of ''B. subtilis'' into [[sporulation]] at high salinity.
| |
| − | * 10:15 - 10:30 – Tsutomu Sato, Tokyo, Japan
| |
| − | ** Developmentally-regulated prophage excisions reconstitute genes required for [[sporulation]] in spore-forming bacteria.
| |
| | | | |
| − | === Session VB Antimicrobials/ Drug research (Sala B)=== | + | ==12:30 – 14:30 Lunch and Poster Session 2 == |
| − | CHAIR: Olaf Schneewind
| |
| − | * 8:30 - 8:45 – Eric A. Johnson, Madison, USA
| |
| − | ** Characterization of a novel chimeric Botulinum neurotoxin.
| |
| − | * 8:45 - 9:00 – [[Oscar Kuipers]], Groningen, Netherlands
| |
| − | ** Cycling with lantibiotics, and potentiating them against Gram-negative pathogens.
| |
| − | * 9:00 - 9:15 – A. L. Flores-Mireles, St. Louis, USA
| |
| − | ** A novel therapy that prevents and resolves ''E. faecalis'' catheter-associated urinary tract infections.
| |
| − | * 9:15 - 9:30 – Alexandra Gruss, Jouy-en-Josas, France
| |
| − | ** Strategies used by ''Staphylococcus aureus'' to bypass FASII-targeted antimicrobials.
| |
| − | * 9:30 - 9:45 – Hanne Ingmer, Frederiksberg, Denmark
| |
| − | ** The ''Staphylococcus aureus agr'' [[quorum sensing]] system as a target for anti-virulence therapy.
| |
| − | * 9:45 - 10:00 – Grace Spatafora, Middlebury, USA
| |
| − | ** Characterizing the SloR-DNA binding interface in ''S. mutans'': A target for rational drug design?
| |
| − | * 10:00 - 10:15 – C. Gallay, Groningen, Netherlands
| |
| − | ** Lack of pAp phosphatase and inhibition of lipid precursors synthesis lead to mislocalization of key [[cell division]] proteins in ''Streptococcus pneumoniae''.
| |
| − | * 10:15 - 10:30 – Yoann Le Breton, College Park, MD, USA
| |
| − | ** Using ''Tn''-seq analyses of divergent group A streptococcal isolates for whole-genome studies of fitness and pathogenesis.
| |
| | | | |
| − | * 10:30 - 11:00 - COFFEE BREAK | + | ==Session 7 – Antibiotics 2 == |
| | + | CHAIR: [[Kevin Devine]] |
| | + | * 14:30 Auke J. van Heel |
| | + | ** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins |
| | + | * 14:45 Amanda Y. van Tilburg |
| | + | ** ''Bacillus subtilis'' as heterologous production host for lantibiotics |
| | + | * 15:00 Nina Lautenschlaeger |
| | + | ** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics |
| | + | * 15:15 Marjorie Gibbon |
| | + | ** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis'' |
| | | | |
| − | == Session VI: Stress == | + | == 15:30 – 16:00 Tea and Coffee == |
| − | CHAIR: Indranil Biswas
| |
| − | * 11:00 - 11:15 – Zehava Eichenbaum, Atlanta, USA
| |
| − | ** Preventing the red menace: the contributions of streptococcal ''pefRCD'' operon in heme stress survival.
| |
| − | * 11:15 - 11:30 – Barbara Spellerberg, Ulm, Germany
| |
| − | ** A Streptococcal NRAMP homolog is crucial for the survival of ''Streptococcus agalactiae'' under low pH conditions.
| |
| − | * 11:30 - 11:45 – Agnes Fouet, Paris, France
| |
| − | ** [[PerR]] is necessary for full virulence of ''Streptococcus agalactiae''.
| |
| − | * 11:45 - 12:00 – Melissa E. Reardon-Robinson, Houston, TX, USA
| |
| − | ** Oxidative folding of virulence determinants in Gram-positive bacteria.
| |
| | | | |
| − | * 12:30 – 14:00 LUNCH | + | == Session 8 – Cereus Group == |
| | + | CHAIR: [[Cinzia Calvio]] |
| | + | * 16:00 Monika Ehling-Schulz |
| | + | ** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains |
| | + | * 16:15 Nick Waterfield |
| | + | ** ''Bacillus cereus'' G9241 – to anthrax and back again |
| | + | * 16:30 Ludivine Rousset |
| | + | ** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187 |
| | + | * 16:45 Jan Maarten van Dijl |
| | + | ** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''? |
| | | | |
| − | == Session VII: Toxins & antibiotics/ Protection & Resistance == | + | == 17:00 Closing Remarks== |
| − | CHAIR: Sandrine Auger
| |
| − | * 13:40 - 13:55 – N. Jahn, Jena, DE
| |
| − | ** Against the mainstream: The type I toxin [[BsrG]] from ''Bacillus subtilis'' does not disrupt membrane potential although it is recruited to the cell membrane
| |
| − | * 14:00 - 14:15 –Yazen Yaseen, Lille, FR
| |
| − | ** Comparative study of fengycin promoters using green fluorescent protein (GFP) fusion marker
| |
| − | * 14:20 - 14:35 –Luminita Ciolacu, KEMIN, BE
| |
| − | ** Lipopeptides of ''Bacillus subtilis'' PB6 - A comparison of two phenotypes
| |
| − | * 14:40 - 14:55—Elrike Frenzel, Groningen, NL
| |
| − | ** Single cell profiling of cereulide toxin producing ''Bacillus cereus''
| |
| − | * 15:00 - 15:15 – [[Anne-Brit Kolsto|Anne-Brit Kolstø]], Oslo, NO
| |
| − | ** The secret lives of bacterial efflux transporter proteins
| |
| − | * 15:20 - 15:35 – [[Susanne Gebhard]], Bath, UK
| |
| − | ** Need-based activation of antibiotic resistance by a flux-sensing mechanism
| |
| − | * 15:40 - 16:00 – COFFEE BREAK
| |
| | | | |
| − | == Session VIII: Biofilm & Secretion == | + | == 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs == |
| − | CHAIR: [[Kevin Devine]]
| |
| − | * 16:00 - 16:15 – [[Akos T Kovacs]], University of Jena, DE
| |
| − | ** Rise to the surface: importance of motility and aerotaxis in pellicle biofilm development
| |
| − | * 16:20 - 16:35 – Cinzia Calvio, University of Pavia, IT
| |
| − | ** Four “y” genes in ''B. subtilis'' genome encode γ-PGA hydrolases
| |
| − | * 16:40 - 16:55 – Stavroula Balomenou, University of Crete, GR
| |
| − | ** Distinct functions of polysaccharide deacetylases in physiology, virulence and [[biofilm formation]] of ''Bacillus anthracis''
| |
| − | * 17:00 - 17:15 – Rita Cruz, DSM Delft, NL
| |
| − | ** Impact of secretion and wall stress on [[protein secretion]] by ''Bacillus subtilis''
| |
| − | * 17:20 - 17:35 – Alexandria Holland, Bath University, UK
| |
| − | ** [[Protein secretion]] in ''Bacillus thermoglucosidasius''
| |
| − | * 17:40 - 17:55 – Sara Kesel, University of Munich, DE
| |
| − | ** Carbohydrate-coating reduces adhesion of biofilm forming ''Bacillus subtilis'' to gold surfaces
| |
| − |
| |
| − | * 18:00 Drinks
| |
| | | | |
| − | * 19:00 Dinner
| |
| | | | |
| | = END OF MEETING = | | = END OF MEETING = |
