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= Wednesday 10th April 2013 =
 
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▪ 8:00 – 9.00 REGISTRATION
 
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▪ 9:00 – 9:10 – Welcome Introduction
 
  
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== Session I Metabolism ==
+
= Tuesday 12th June =
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CHAIR: [[Leendert Hamoen]]
 
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* 9:10 – 9:25 – [[Ken-Ichi Yoshida]], Kobe University, Japan
 
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** [[Bacillus subtilis]] possesses two distinct [[tpi|triosephosphate isomerases]]
 
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* 9:30 – 9:45 – Kambiz Morabbi Heravi, University of Stuttgart, DE
 
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** Mannitol utilization system of [[Bacillus subtilis]]: activation of the ''mtl'' promoters by [[MtlR]]
 
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* 9:50 – 10:05 – Marian Wenzel, University of Stuttgart,DE
 
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** Development of a self-inducible ''Bacillus subtilis'' expression system for application in high-cell-density fermentations.
 
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* 10:10 – 10:25 – [[Elisabeth Hartig]], Technical University Braunschweig, DE
 
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** Transcriptional activation by the [[AlsR]] regulator of ''Bacillus subtilis'' comprises effector binding, oligomerization, DNA binding and DNA bending
 
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* 10:30 – 10:50 – COFFEE BREAK
 
  
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Session II Biofilms
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* 8:30 – 8:55 Registration
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CHAIR: Dirkjan Scheffers
+
* 8:55 Welcome - Chancellors’ Building, room 1.12
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10:50 – 11:05 – Laura Hobley, University of Dundee, UK
 
−
▪ BSLA is a novel self-polymerising protein that forms a hydrophobic layer around Bacillus subtilis biofilms
 
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11:10 – 11:25 – Akos Kovacs, University of Jena, DE
 
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▪ Living on the surface: Biofilm formation and surface motility of Bacillus subtilis
 
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11:30 – 11:45 – Ole Okstad, University of Oslo, NO
 
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▪ Cyclic diguanylate (c-di-GMP) regulation of biofilm formation in Bacillus subtilis
 
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11:50 – 12:05 – Jörg Stülke, University of Göttingen, DE
 
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▪ c-di-AMP, an essential signalling nucleotide in Bacillus subtilis
 
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12:10 – 12:25 – Lynne Cairns, University of Dundee, UK
 
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▪ Investigation of the role of the motility protein, YvyG, and potential regulation by tyrosine phosphorylation in Bacillus subtilis
 
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12:30 – 13:40 LUNCH (+ BACIP MEETING)
 
  
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Session III: Beyond Bacillus subtilis, a focus on non-subtilis species
+
== Session 1 Regulation==
−
CHAIR: Jan Maarten van Dijl
+
CHAIR: David Leak
−
13:40 – 13:55 – Anne-Brit Kolstø, University of Oslo, NO
+
* 09:00 [[Ciaran Condon]]
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▪ TBA
+
** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]]
−
14:00 – 14:15 – Rebecca Biedendieck, Technische Universitat, Braunschweig, DE
+
* 09:15 [[Roland Hartmann]]
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▪ Production and secretion of recombinant proteins in Bacillus megaterium
+
** Function and regulation of two 6S RNAs in Bacillus subtilis
−
14:20 – 14:35 – Per Bullough, University of Sheffield, UK
+
* 09:30 [[Matthias Mack]]
−
▪ Surface architecture of endospores of the Bacillus cereus/anthracis/thuringiensis family at the subnanometer scale.
+
** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis''
−
14:40 – 14:55 – Susanne Pohl, Newcastle University, UK
+
* 09:45 Hermann Rath
−
▪ Oxidative stress in Bacillus anthracis
+
** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis''
−
15:00 – 15:15 –Mette Dines-Cantor, Chr. Hansen A/S, Hørsholm, DK
+
* 10:00 Laura Teichmann
−
▪ Screening for new Bacillus-based probiotic feed additives for the pig industry.
+
** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]]
−
15:20 – 15:35 – Jurgen Seppen, Amsterdam Medical Centre, NL
+
* 10:15 Sylvain Durand
−
▪ The utility Bacillus subtilis for intestinal gene transfer.
+
** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation
−
15:40 – 16:00 – COFFEE BREAK
 
  
−
Session IV: Spores/sporulation
+
== 10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer==
−
CHAIR: Nicola Stanley-Wall
 
−
16:00 – 16:15 – Stanley Brul, University of Amsterdam, NL
 
−
▪ Functional genomics for food preservation: inhibiting bacterial spore germination
 
−
16:20 – 16:35 – Ewa Bukowska-Faniband, University of Lund, SE
 
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▪ Cortex synthesis during Bacillus subtilis sporulation depends on the transpeptidase activity of SpoVD
 
−
16:40 – 16:55 – Robyn EIJLANDER, University of Groningen, NL
 
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▪ SporeWeb: Interactive visualization of gene regulatory networks during the complete sporulation cycle of Bacillus subtilis
 
−
17:00 – 17:15– Katie Jameson, University of York, UK
 
−
▪ Regulating DnaA to maintain diploidy at the onset of sporulation
 
−
17:20 – 17:35 – Katja Nagler, German Aerospace Centre, Cologne, DE
 
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▪ High salinity has negative effects on Bacillus subtilis spore germination and outgrowth
 
−
17.40 – 17.55– Patrik Florek, Slovak Academy of Sciences, SK
 
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▪ Characterization of Bacillus three-component SpoIISABC toxin-antitoxin system
 
−
18.00 – 19.30 BACELL STEERING GROUP MEETING
 
  
−
19:30 – WINE RECEPTION AND DINNER AT THE Great North Museum, Barras Bridge
+
== Session 2 [[Cell division]]==
 +
CHAIR:  TBA
 +
* 11:00 [[Henrik Strahl]]
 +
** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains
 +
* 11:15 Jeanine Rismondo
 +
** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
 +
* 11:30 Edward de Koning
 +
** [[Divisome]] maturation in ''Bacillus subtilis'' single cells
 +
* 11:45 Seamus Holden
 +
** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]]
 +
* 12:00 [[Dirk-Jan Scheffers]]
 +
** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]]
 +
* 12:15 Yongqiang Gao
 +
** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii''
  
−
Thursday April 11th 2013
 
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Session V: Synthetic Biology
 
−
CHAIR: Thomas Wiegert
 
−
9:00 – 9:15 – Elbrich Hendricks, University of Groningen, NL
 
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▪ iGEM team Groningen 2012: Food Wardens – Grand Prize Winners
 
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9:20 – 9:35 – Francois Coutte, University of Lille, FR
 
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▪ Genetic engineering of Bacillus subtilis assisted by computational modelling to overproduce lipopeptide biosurfactants
 
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9:40 – 9:55 – Maarten Mols, University of Groningen, NL
 
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▪ Improving the Bacilllus cell factory by cell envelope engineering
 
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10:00 – 10:15 – Tjeerd van Ris, DSM, Delft, NL
 
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▪ Improved enzyme production by codon pair optimization
 
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10:20 – 10:35 – Alexander Webb, Imperial College London, UK
 
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▪ Parasight
 
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10:40 – 11:00 – COFFEE BREAK
 
  
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Session VI: Cell walls and secretion
+
== 12:30 – 14:30 Lunch and Poster Session 1==
−
CHAIR: Ole Okstad
 
−
11:00 – 11:15 – Patricia Dominguez-Cuevas, Newcastle University, UK
 
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▪ Actin cytoskeleton Mbi homologue coordinates cell wall hydrolases and LytE activity during cell elongation.
 
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11:20 – 11:35 – David Noone, Trinity College Dublin, IE
 
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▪ Several regulatory mechanisms combine to make expression and cell association of the CwIO D,L-endopeptidase-type autolysin responsive to growth conditions in Bacillus subtilis
 
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11:40 – 11:55 – Dirk-Jan Scheffers, University of Groningen, NL
 
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▪ Substrate availability guides peptidoglycan synthesis
 
−
12:00 – 12:15 – Thomas Wiegert, University of Applied Sciences Zittau, DE
 
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▪ Influence of the intramembrane cleaving protease RasP on protein secretion in Bacillus subtilis
 
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12:20 – 12:35 – Vivianne Goosens, University Medical Centre Groningen, NL
 
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▪ A role for TatAC in Bacillus subtilis twin-arginine protein translocation
 
−
12:40 – 13:40 – LUNCH
 
  
−
Session VII: Regulation & Replication
+
== Session 3 – Interesting Biology ==
−
CHAIR: Henrik Strahl
+
CHAIR: [[Colin Harwood]]
−
13:40 – 13:55 – Sara Kesel, Ludwig-Maximilians-University, DE
+
* 14:30 [[Jörg Stülke]]
−
▪ Immediate and heterogeneous response of the LiaFSR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin
+
** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors
−
14:00 – 14:15 –Jakob Engman, Lund University, SE
+
* 14:45 Hannah Gaimster
−
• Aggregation of the YjbH adaptor protein as a mechanism of Spx regulation.
+
** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis''
−
14:20 – 14:35 –Fabian Commichau, University of Gottingen, DE
+
* 15:00 Alexandre Deloupy
−
▪ Essential genes in Bacillus subtilis: a re-evaluation after 10 years
+
** Stochastic gene expression in Bacillus subtilis
−
14:40 – 14:55– Thorsten Mascher, Ludwig-Maximilians-University, DE
+
* 15:15 Sabine Schneider
−
▪ (Tools for studying the) Regulatory dynamics of peptide antibiotic detoxification modules in Bacillus subtilis
+
** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening
−
15:00 – 15:15 – Vladimir Bidnenko, INRA, Jouy en Josas, FR
+
* 15:30 [[Ken-ichi Yoshida]]
−
▪ Distinct activities of co-essential Bacillus subtilis flap-endonucleases, Pol I and YpcP, in DNA replication and repair
+
** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
−
15:20 – 15:35 – Panos Soultanas, University of Nottingham, UK
+
* 15:45 Anna A. Toymentseva
−
▪ Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex during lagging strand DNA replication in Bacillus subtilis
+
** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element
−
15:40 – 16:00 – COFFEE BREAK
 
  
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Session VIII: Division
+
==16:00 – 16:30 Tea and Coffee ==
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CHAIR: Alan Nielson
 
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16:00 – 16:15 – Peter Graumann, Universitat Freiburg, DE
 
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▪ Movement of up to 3.4mm long MreB filaments at various angles underneath the cell membrane and their intrinsic membrane affinity
 
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16:20 – 16:35 – Hiraku Takada, Tokyo University of Agriculture, Japan
 
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▪ Involvement of essential lipid synthetic enzyme, PlsX, in the cell division machinery
 
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16:40 – 16:55 – Ilkay Celik, Newcastle University, UK
 
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▪ Bacillus minimal divisome
 
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17:00 – 17:15 – Robert Cleverley, Newcastle University, UK
 
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▪ Structure of the major divisome protein EzrA
 
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17:20 – 17:35 – Alex Dajkovic, University of California Irvine, USA
 
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▪ Organization of FtsZ polymers in living Bacillus subtilis cells
 
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17:40 – 17:55 – Romain Mercier, Newcastle University, UK
 
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▪ Excess membrane synthesis drives a primitive mode of cell proliferation
 
−
 
 
−
END OF MEETING
 
−
 
 
−
=Tuesday April 24th 2012 – Morning=
 
−
 
 
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* 8:00-8:45 - REGISTRATION
 
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* 9:00-9:10 – Welcome Introduction [[Kevin Devine]]
 
−
 
 
−
==Session I: Modeling and Networks ==                                                                                                                 
 
−
CHAIR: Sierd Bron
 
 
   
 
   
−
* 9:10-9:30 – BACELL Systems – Past, Present, Future
+
==Session 4 – Antibiotics 1 ==
−
** [[Jan Maarten van Dijl]] (University Medical Center Groningen)
+
CHAIR: [[Ulrike Mäder]]
−
 
+
* 16:30 Carolin Kobras
−
* 9:30-9:50 – Unraveling the [[ncRNA|Small Regulatory RNA]] Network of ''Bacillus subtilis''
+
** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis''  
−
** Ruben Mars (University Medical Center Groningen)
+
* 16:45 Luiza P. Morawska
−
 
+
** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance
−
* 9:50-10:10 – A Computational [[Stressosome]] Model Consolidates Hypotheses about Environmental Activation of [[SigB]] the General Stress response
+
* 17:00 Mary K. Phillips-Jones
−
** Ulf Liebal (University of Rostock)
+
** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
−
 
+
* 17:15 Gabriela Henriques
−
* 10:10-10:30 – Reconciling Molecular Regulatory Mechanisms with Noise Patterns of Bacterial Metabolic Promoters in Induced and Repressed States
+
** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis.
−
** Matthieu Jules (Institut Micalis, INRA)
 
−
 
 
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* 10:30 – 11:00 – COFFEE BREAK
 
−
 
 
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== Session II: [[Cell wall degradation/ turnover|Cell Wall]] ==
 
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CHAIR: [[Colin Harwood]]
 
−
 
 
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* 11:00-11:20 – The [[WalR]]/[[WalK]], [[PhoP]]/[[PhoR]] and [[SigI]]/[[RsgI]] Regulatory Systems of ''Bacillus subtilis'' Cooperate to Control Cell Wall Metabolism during Growth and Under Stress Conditions
 
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** Letal Salzberg (Trinity College Dublin)
 
−
 
 
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* 11:20-11:40 – Adaptation of ''Bacillus subtilis'' to High Salinity: Osmotic Induction of the Cell Wall Hydrolase [[YqiI]]
 
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** Kathleen Fischer (Philipps-Universität Marburg)
 
−
 
 
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* 11:40-12:00 – Regulatory and Cellular Dynamics of the Lia-Response of ''Bacillus subtilis''
 
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** [[Thorsten Mascher]] (Ludwig-Maximilians-University Munich)
 
−
 
 
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* 12:00-12:20 – [[SepF]] is a New Membrane Anchor for the Key [[Cell division|Cell Division]] Protein [[FtsZ]]
 
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** Ilkay Celik (Newcastle University)
 
−
 
 
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* 12:20-12:40 – The Bacterial [[MreB]] Cytoskeleton Organizes the Cell Membrane
 
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** Henrik Strahl (Newcastle University)
 
−
 
 
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* 12:40 – 14:20 LUNCH (+ BACIP MEETING)
 
−
 
 
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=Tuesday April 24th 2012 – Afternoon=
 
−
 
 
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== Session III: Adaptation, [[Sporulation]] and [[DNA replication|DNA Replication]] ==
 
−
CHAIR: [[Ulrike Mäder]]
 
−
 
 
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* 14:20-14:40 – Selecting Better Bet Hedging ''Bacillus'' Strains
 
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** Jeroen Siebring (University of Groningen)
 
−
 
 
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* 14:40-15:00 – Spore Coat Proteins: Self-Assembly Properties and Protein-Protein [[SubtInteract|Interactions]]
 
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** Daniela Krajčíková (Slovak Academy of Sciences)
 
−
 
 
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* 15:00-15:20 – [[Spo0A]] links [[DNA replication|DNA Replication]] with [[Sporulation]] by Direct Binding to the Origin of Replication in ''Bacillus subtilis''  
 
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** Mirjam Boonstra (University of Groningen)
 
−
 
 
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** 15:20-15:40 – DSB Repair Pathway is Required for Viability of the [[smc|SMC]]-[[ScpA]]-[[ScpB]] Depleted Strain
 
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** Etienne Dervyn (Institut Micalis, INRA)
 
−
 
 
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* 15:40-16:10 - COFFEE BREAK
 
−
 
 
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== Session IV: Antibiotics ==
 
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CHAIR: [[Eugenio Ferrari]]
 
−
 
 
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* 16:10-16:30 – Regulated Expression of a Multidrug-[[ABC transporters|ABC Transporter]] – The ''[[yheH]]-[[yheI]]-[[yheJ]]'' Operon
 
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** Ewoud Reilman (University of Groningen)
 
−
 
 
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* 16:30-16:50 – Signal Transduction in Antimicrobial Peptide Detoxification Modules of ''Bacillus subtilis'': Interaction between [[ABC transporters|ABC Transport]] and Sensor Kinase
 
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** Susanne Gebhard (Ludwig-Maximilians-University Munich)
 
−
 
 
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* 16:50-17:10 – Structure-Function Relationship of the Lantibiotic Immunity-Protein SpaI
 
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** Sophie Bochmann (Goethe University Frankfurt)
 
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* 17:10-17:30 – Structure, Biosynthesis and Properties of Kurstakins, Nonribosomal Lipopeptides from ''Bacillus'' spp.
 
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** Philippe Jacques (Universite de Lille)
 
−
 
 
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== 17.30-18.30 BACELL STEERING GROUP MEETING ==
 
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== 19:30 – WINE RECEPTION ==
 
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== 20:00 - DINNER ==
 
−
 
 
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= Wednesday April 25th 2012 - Morning =
 
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== Session V: Application ==
 
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CHAIR: [[Jörg Stülke]]
 
−
 
 
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* 9:00-9:20 – ''Bacillus subtilis'' Cell Factory Producing Scyllo-Inositol, A Potential Therapeutic Agent for Alzheimer’s Disease
 
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** [[Ken-ichi Yoshida]] (Kobe University)
 
−
 
 
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* 9:20-9:40 – Developing an Enzyme Discovery Tool for ''Bacillus subtilis''
 
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** Tjeerd van Rij (DSM)
 
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* 9:40 – 10:00 - Use of ''Bacillus amyloliquefaciens'' for Control of Plant Stress
 
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** Johan Meijer (University of Uppsala)
 
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* 10:00 – 10:20 – Phenotypic Heterogeneity during Heterologous Protein Production in ''Bacillus megaterium''
 
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** Rebekka Biedendieck (Technische Universität Braunschweig)
 
−
 
 
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* 10:20-10:40 – Absolute Protein Quantification - Application in ''Bacillus subtilis''
 
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** [[Dörte Becher]] (Ernst-Moritz-Arndt Universität Greifswald)
 
  
−
10:40-11:00  - COFFEE BREAK
+
== Free evening in Bath ==
  
−
== Session VI: RNA Metabolism and Regulation ==
+
= Wednesday 13th June =
−
CHAIR: [[Uwe Völker]]
 
  
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* 11:00-11:20 – Three Essential Ribonucleases [[rny|RNase Y]], [[rnjA|J1]] and [[rnc|III]] Control the Abundance of a Majority of ''B. subtilis'' mRNAs
+
== Session 5 Biotechnology ==
−
** [[Ciaran Condon|Ciarán Condon]] (Institut de Biologie Physico-Chimique CNRS)
+
CHAIR:  Anne Breüner
 +
* 9:00 Andreas Knapp
 +
** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis''
 +
* 9:15 Alexandria Holland
 +
** Investigating protein secretion in ''Geobacillus thermoglucosidasius''
 +
* 9:30 Matthew Styles
 +
** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
 +
* 9:45 Luca Longanesi
 +
** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains
 +
* 10:00 Matteo Cavaletti
 +
** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
 +
* 10:15 Ioannis Mougiakos
 +
** Characterizing a thermostable Cas9 for bacterial genome editing and silencing
  
−
* 11:20-11:40 – The Effects of [[RpoE]] and [[HelD]] on [[RNA polymerase|RNA Polymerase]] from ''Bacillus subtilis''
+
== 10:15 - 10:45 Tea and Coffee ==
−
** [[Libor Krasny|Libor Krásný]] (Academy of Sciences of the Czech Republic)
 
  
−
* 11:40 – 12:00 – Dynamic Localization of an [[LicT|RNA-Binding Transcription Factor]] in ''Bacillus subtilis''  
+
== Session 6 - [[Sporulation]] and development ==
−
** Fabian Rothe (University of Göttingen)
+
CHAIR:  TBC
 +
* 10:45 [[Imrich Barák]]
 +
** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis''
 +
* 11:00 Munehiro Asally
 +
** Quality monitoring during [[sporulation]] in ''B. subtilis''
 +
* 11:15 [[Ilka Bischofs]]
 +
** Phenotypic memory links different stages of the ''B. subtilis'' life cycle
 +
* 11:30 [[Akos Kovacs]]
 +
** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
 +
* 11:45 [[Sven Halbedel]]
 +
** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division''
 +
* 12:00 Sofia Arnaouteli
 +
** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]]
 +
* 12:15 Karin Bjerre
 +
** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs
  
−
* 12:00 – 12:20 – Requirements for the High-Frequency Activation of the Cryptic ''[[gudB]]'' Glutamate Dehydrogenase Gene in ''Bacillus subtilis''
+
==12:30 – 14:30 Lunch and Poster Session 2 ==
−
** Fabian Commichau (Georg-August-Universität Göttingen)
 
  
−
* 12:20-12:40 – The Anaerobic Formation of Acetoin Regulated by the Transcriptional Regulator [[AlsR]] – Part of [[pH homeostasis|pH Homeostasis]] in ''Bacillus subtilis''  
+
==Session 7 – Antibiotics 2 ==
−
** [[Elisabeth Härtig]] (TU Braunschweig)
+
CHAIR:  [[Kevin Devine]]
 +
* 14:30 Auke J. van Heel
 +
** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
 +
* 14:45 Amanda Y. van Tilburg
 +
** ''Bacillus subtilis'' as heterologous production host for lantibiotics
 +
* 15:00 Nina Lautenschlaeger
 +
** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics
 +
* 15:15 Marjorie Gibbon
 +
** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis''
  
−
12:40-14:00 – LUNCH
+
== 15:30 – 16:00 Tea and Coffee ==
  
−
= Wednesday April 25th 2012 - Afternoon=
+
== Session 8 – Cereus Group ==
−
== EU BaSynthec Synthetic Biology Symposium ==
+
CHAIR: [[Cinzia Calvio]]
−
CHAIR: [[Kevin Devine]]
+
* 16:00 Monika Ehling-Schulz
 +
** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
 +
* 16:15 Nick Waterfield
 +
** ''Bacillus cereus'' G9241 – to anthrax and back again
 +
* 16:30 Ludivine Rousset
 +
** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187
 +
* 16:45 Jan Maarten van Dijl
 +
** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''?
  
−
* 14:00-14:10 – Introduction – [[Philippe Noirot]] (INRA)
+
== 17:00 Closing Remarks==
−
* 14:10-14:40 – Enhanced Recombinant Protein Productivity by Genome Reduction in ''Bacillus subtilis'' - [[Naotake Ogasawara]] (Nara Institute)
 
−
* 14:40-15:10 – Computational and Bioinformatics Approaches to Enabling Synthetic Biology - Anil Wipat (Newcastle University)
 
−
* 15:10-15:40 – Highly Modified Peptides by Synthetic Biology Approaches - [[Oscar Kuipers]] (Groningen University)
 
  
−
* 15:40-16:10 – COFFEE BREAK
+
== 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs ==
  
−
* 16:10-16:40 – ''Bacillus subtilis'' Minimal Genome Work in Europe - [[Philippe Noirot]] (INRA)
 
−
* 16:40-17:10 – View of Novozymes on Synthetic Biology - Allen Kent Nielsen (Novozymes)
 
−
* 17:10-17:40 – View of DSM on Synthetic Biology - [[Zoltan Pragai|Zoltán Prágai]] (DSM)
 
−
* 17:40-17:50 – Wrap up / end of workshop – [[Philippe Noirot]] (INRA)
 
  
 +
= END OF MEETING =
  
  
 
=Back to [[Main Page|SubtiWiki]]=
 
=Back to [[Main Page|SubtiWiki]]=

Latest revision as of 15:38, 4 June 2018

Tuesday 12th June

  • 8:30 – 8:55 Registration
  • 8:55 Welcome - Chancellors’ Building, room 1.12

Session 1 Regulation

CHAIR: David Leak

  • 09:00 Ciaran Condon
    • Suppression of the essential nature of RNase M16 (YqfG), required for 3' maturation of B. subtilis 16S ribosomal RNA, by deletion of RNase R
  • 09:15 Roland Hartmann
    • Function and regulation of two 6S RNAs in Bacillus subtilis
  • 09:30 Matthias Mack
    • A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis
  • 09:45 Hermann Rath
    • A SigB-dependent antisense RNA affects osmotic induction of opuB expression in Bacillus subtilis
  • 10:00 Laura Teichmann
    • Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor GbsR
  • 10:15 Sylvain Durand
    • sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation

10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer

Session 2 Cell division

CHAIR: TBA

  • 11:00 Henrik Strahl
    • Bacillus subtilis does not form microscopically detectable cardiolipin domains
  • 11:15 Jeanine Rismondo
    • Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
  • 11:30 Edward de Koning
    • Divisome maturation in Bacillus subtilis single cells
  • 11:45 Seamus Holden
  • 12:00 Dirk-Jan Scheffers
  • 12:15 Yongqiang Gao
    • Cell division in the cell wall-less bacterium Acholeplasma laidlawii


12:30 – 14:30 Lunch and Poster Session 1

Session 3 – Interesting Biology

CHAIR: Colin Harwood

  • 14:30 Jörg Stülke
    • DNA topoisomerases in Bacillus subtilis: A tale on mutants and suppressors
  • 14:45 Hannah Gaimster
    • Lethal depletion of essential cell envelope proteins can be rescued by slowing DNA replication in Bacillus subtilis
  • 15:00 Alexandre Deloupy
    • Stochastic gene expression in Bacillus subtilis
  • 15:15 Sabine Schneider
    • Development of a reporter gene system to characterise riboswitch function and to identify riboswitch modulators by high-throughput screening
  • 15:30 Ken-ichi Yoshida
    • Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
  • 15:45 Anna A. Toymentseva
    • Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element

16:00 – 16:30 Tea and Coffee

Session 4 – Antibiotics 1

CHAIR: Ulrike Mäder

  • 16:30 Carolin Kobras
    • Exploring the substrate specificity of the antimicrobial peptide resistance transporter BceA-BceB in Bacillus subtilis
  • 16:45 Luiza P. Morawska
    • Preadaptation of Bacillus subtilis to mild osmostress contributes to increased antibiotic resistance
  • 17:00 Mary K. Phillips-Jones
    • Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
  • 17:15 Gabriela Henriques
    • Towards the understanding of the regulation of SppA by YteJ in Bacillus subtilis.

Free evening in Bath

Wednesday 13th June

Session 5 Biotechnology

CHAIR: Anne Breüner

  • 9:00 Andreas Knapp
    • The spacer region in the 5´-UTR strongly affects recombinant protein production in Bacillus subtilis
  • 9:15 Alexandria Holland
    • Investigating protein secretion in Geobacillus thermoglucosidasius
  • 9:30 Matthew Styles
    • Engineering Parageobacillus for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
  • 9:45 Luca Longanesi
    • γ-PGA production through Consolidated Bioprocessing in engineered B. subtilis lab strains
  • 10:00 Matteo Cavaletti
    • Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
  • 10:15 Ioannis Mougiakos
    • Characterizing a thermostable Cas9 for bacterial genome editing and silencing

10:15 - 10:45 Tea and Coffee

Session 6 - Sporulation and development

CHAIR: TBC

  • 10:45 Imrich Barák
    • What we (don’t) know about the asymmetric septum in Bacillus subtilis
  • 11:00 Munehiro Asally
  • 11:15 Ilka Bischofs
    • Phenotypic memory links different stages of the B. subtilis life cycle
  • 11:30 Akos Kovacs
    • Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
  • 11:45 Sven Halbedel
    • Novel gpsB suppressor genes contributing to regulatory proteolysis and cell division
  • 12:00 Sofia Arnaouteli
  • 12:15 Karin Bjerre
    • Investigating of Bacillus subtilis and Bacillus amyloliquefaciens spores and vegetative cells in fecal samples from pigs

12:30 – 14:30 Lunch and Poster Session 2

Session 7 – Antibiotics 2

CHAIR: Kevin Devine

  • 14:30 Auke J. van Heel
    • BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
  • 14:45 Amanda Y. van Tilburg
    • Bacillus subtilis as heterologous production host for lantibiotics
  • 15:00 Nina Lautenschlaeger
    • A novel heterologous whole-cell biosensor in Bacillus subtilis for the comprehensive detection of b-lactam antibiotics
  • 15:15 Marjorie Gibbon
    • Towards understanding signalling between the bacitracin resistance transporter BceA-BceB and histidine kinase BceS of Bacillus subtilis

15:30 – 16:00 Tea and Coffee

Session 8 – Cereus Group

CHAIR: Cinzia Calvio

  • 16:00 Monika Ehling-Schulz
    • Bacillus cereus, a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
  • 16:15 Nick Waterfield
    • Bacillus cereus G9241 – to anthrax and back again
  • 16:30 Ludivine Rousset
    • Oligotrophy induces phenotypic diversification of Bacillus cereus AH187
  • 16:45 Jan Maarten van Dijl
    • Can Bacillus thuringiensis and other microorganisms isolated from chronic wounds ‘pacify’ Staphylococcus aureus?

17:00 Closing Remarks

19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs

END OF MEETING

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