Difference between revisions of "Program"

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=Sunday, June 19, 2011 – Afternoon=
 
  
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= Tuesday 12th June =
* 2:00              Welcome remarks – [[Jim Hoch]]
 
 
==Physiology==                                                                                                                 
 
CHAIR: [[Josef Deutscher]]
 
 
* 2:15 – 2:30 T1, Elaine Milohanic, INRA and AgroParis Tech, Thiverval-Grignon, France
 
** [[ManR]] regulates the expression of the main ''Listeria monocytogenes'' glucose/mannose transporter and uses a second glucose transporter as substrate sensor. 
 
 
 
* 2:30 – 2:45 T2, [[Boris Görke]], Dept. of General Microbiology, Georg-August University of Göttingen, Göttingen, Germany
 
** [[Crh]], the homolog of the phosphor-carrier protein HPr, regulates a glycolytic bypass in ''Bacillus subtilis''. 
 
 
* 2:45 – 3:00 T3, Jean-Michel Jault, Institut de Biologie Structurale, Grenoble, France
 
** The unusual activity of a [[GTP-binding proteins|GTPase]] from ''Bacillus subtilis'', [[YphC]] (or [[EngA]]), involved in ribosome biogenesis.
 
 
* 3:00 – 3:15 T4, Yuka Kazo, Laboratory of Molecular Genetics, Department of Life Science, Rikkyo University, Tokyo, Japan
 
** Analysis of dimerization of 70S ribosome, and ''[[yvyD]]'' gene during stationary phase in ''Bacillus subtilis''. 
 
 
 
* 3:15 – 3:30 T5, Donald A. Morrison, Dept. of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
 
** Regulation of the competence regulon in Group A and Group B streptococci:  Pyogenic Type II ComR receptors recognize small species-specific peptide pheromones when expressed in a heterologous host.
 
 
* 3:30 – 3:45 T6, Nathalie Campo, Centre national de la Recherche Scientifique, Toulouse, France
 
** X-state (competence) development causes transient cell cycle alterations in ''Streptococcus pneumoniae''. 
 
 
 
* 3:45 – 4:00 T7, Maria C. Mansilla, Instituto de Biología Molecular y Celular, Univ. Nac.de Rosario, Rosario, Argentina
 
** A novel pathway for lipoic acid synthesis in Gram-positive bacteria.
 
 
* 4:00 – 4:15 T8, [[Jörg Stülke]], Dept. of General Microbiology, Georg-August- Univeristy Göttingen, Göttingen, Germany
 
** A novel factor controlling bistability in ''Bacillus subtilis'': The [[YmdB]] protein affects [[biofilm formation]] and [[motility and chemotaxis|motility]].
 
 
 
==Genome Engineering ==
 
CHAIR: Mike Rasmussen 
 
 
* 4:45 – 5:00 T9, Robert A. Britton, Dept. of Microbiology and Molecular Genetics, Michigan State University, East Lansing Michigan, USA
 
** Recombineering in lactic acid bacteria. 
 
 
* 5:00 – 5:15 T10, Ghislain Schyns, DSM Nutritional Products, Ltd., Basel, Switzerland
 
** Learning from probiotics to improve biological availability of feed enzymes. 
 
 
* 5:15 – 5:30 T11, Sébastien Potot, DSM Nutritional Products, Biotechnology, Basel, Switzerland
 
** Mixing bacterial genomes to identify critical mutations in ''Bacillus subtilis'' industrial strains.
 
 
* 5:30 – 5:45 T12, Philippe Jacques, Université Lille, France
 
** Environmental factors and pleiotropic regulators influence homologous compound pattern of mycosubtilin produced by ''Bacilius subtilis'' ATCC 6633.
 
 
* 5:45 – 6:00 T13, [[Philippe Noirot]], INRA, Jouy en Josas, France
 
** Systematic identification of dispensable genome parts in ''Bacillus subtilis'' coupled with metabolic model reconstruction. 
 
 
==Welcome Reception  - 7:00 – 9:00  – Grand Hotel & La Pace==
 
 
 
=Monday, June 20, 2011 – Morning=
 
 
 
==Cell Wall I==                                                                                                                     
 
CHAIR: [[Kevin Devine]] 
 
 
 
* 8:15 – 9:00, [[Jeff Errington]], Centre for Bacterial Cell Biology, Newcastle University, Newcastle-upon-Tyne, United Kingdom
 
** Keynote Lecture: Emergence and proliferation of ''B. subtilis'' L-forms. 
 
 
 
* 9:00 – 9:15 T14, Olaf Schneewind, Dept. of Microbiology, University of Chicago, Chicago, Illinois, USA
 
** LytN, a murein hydrolase in the cross wall compartment of ''Staphylococcus aureus'', is required for bacterial growth and envelope assembly.
 
 
* 9:15  – 9:30 T15, Hèléne Bierne, Institut Pasteur, Unité des interactions bactéries-cellules, Inserm, Paris, France
 
** A regulated switch from helical to polar localization of ''Listeria monocytogenes'' cell wall-anchored proteins.
 
 
* 9:30 – 9:45 T16 [[Sven Halbedel]], Dept. of Bacterial Infections, Robert Koch Institute, Wernigerode, Germany 
 
** A role for the membrane curvature sensor [[DivIVA]] in cell separation and virulence of ''Listeria monocytogenes''. 
 
 
 
* 9:45 – 10:00 T17, Teresa Costa, ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
 
** Control of ''Bacillus subtilis'' cell shape by the novel cytoskeletal element [[RodZ]]. 
 
 
 
* 10:00 – 10:15 T18, Julia Domínguez-Escobar, Max Planck Institute of Biochemistry, Martinsried, Germany
 
**Processive movement of [[MreB]]-associated cell wall biosynthetic complexes in bacteria. ''In vivo'' visualization of sidewall biosynthetic machineries in ''Bacillus subtilis''. 
 
 
* 10:15 – 10:30 T19, [[Anne Galinier]], Université de la Méditerranée, Marseille, France
 
** The [[YvcK]] protein is required for morphogenesis via localization of [[ponA|PBP1]] under gluconeogenic growth conditions in ''Bacillus subtilis''.
 
 
 
==Cell Wall II==                                                                                                                     
 
CHAIR: [[Jeff Errington]]
 
 
 
* 11:00 – 11:15 T20, Letal Salzberg, Smurfit Institute of Genetics, Trintiy College Dublin, Dublin, Ireland
 
** [[WalR]]-[[WalK]] ([[YycF]]-[[YycG]])-mediated control of cell wall metabolism in ''Bacillus subtilis'': linking autolysins and actin-like proteins. 
 
 
* 11:15 – 11:30 T21, Hiraku Takada, Tokyo University of Agriculture, Tokyo, Japan
 
** Involvement of essential lipid synthetic enzyme, [[PlsX]], in the cell division machinery.   
 
 
* 11:30 – 11:45 T22, Maria-Halima Laaberki, Dept. of Microbiology and Immunology, Columbia University, New York, New York,  USA
 
** The unexpected role of O-acetylation of peptidoglycan in cell separation and S-layer anchoring in ''Bacillus anthracis''. 
 
 
 
* 11:45 – 12:00 T23, Michel-Yves Mistou, INRA, Institut Micalis, Jouy-en-Josas, France
 
** Outer polysaccharide pellicle: a structural component of Gram positive bacteria cell wall. 
 
 
* 12:00 – 12:15 T24, [[Rick Lewis]], Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom
 
** The decoration of peptidoglycan by teichoic acids: the missing enzymatic step revealed by X-ray crystallography? 
 
 
=Monday, June 20, 2011 – Afternoon=
 
 
 
==Structure==
 
CHAIR: [[Jim Hoch]]
 
 
 
* 2:00 – 2:15 T25, Wayne F. Anderson, Northwestern University CSGID, Chicago, Illinois USA
 
** Applying structural genomics – revealing the bacterial surface one protein structure at a time.
 
 
 
* 2:15 – 2:30 T26, Catarina G. Fernandes, ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
 
** From the crystal structure of the [[Tgl]] transglutaminase to the cross-linking of the spore surface layers.
 
 
 
* 2:30 – 2:45 T27, [[Claes von Wachenfeldt]], Dept. of Biology, Lund University, Lund, Sweden
 
** Redox sensing by [[Rex]] family repressors.
 
 
 
* 2:45 – 3:00 T28, Marion Boudes, IBBMC, Université Paris-Sud, Orsay, France
 
** Structural and functional study of ComE, a key actor in ''S. pneumoniae'' competence.
 
 
 
* 3:00 – 3:15 T29, [[Hendrik Szurmant]], Dept. of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
 
** [[Two-component systems|Sensor histidine kinase]] signaling: An active conformation deduced from integrating genomics, molecular dynamics and mutagenesis.
 
 
 
==[[Sporulation proteins|Sporulation]]/ [[germination]]==
 
CHAIR: [[Charles Moran]]
 
 
 
* 3:45 – 4:00 T30, Michael Young, Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, United Kindom
 
** Multiple orphan histidine kinases interact directly with [[Spo0A]] to control the initiation of endospore formation in ''Clostridium acetobutylicum''.
 
 
 
* 4:00 – 4:15 T31, Lei Shi, INRA-AgroParis Tech, Micalis Institute, Jouy-en-Josas, France
 
** Phosphorylated bacterial recombinase checks chromosome integrity during spore formation.
 
 
 
* 4:15 – 4:30 T32, [[Patrick Piggot]], Dept. Microbiol. & Immunol., Temple University School of Medicine, Philadelphia, Pennsylvania, USA
 
** Compartmentalization of [[SigE|σE]] Activity During Sporulation of ''Bacillus subtilis'': Much Ado About What?
 
 
 
* 4:30 – 4:45 T33, [[Adriano Henriques]], ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
 
** A negative feedback loop that limits the ectopic activation of a cell type-specific sporulation [[sigma factor]] of ''Bacillus subtilis''.
 
 
 
* 4:45 – 5:00 T34, Thierry Doan, Dept. of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, USA
 
** Bacterial membrane fission during sporulation in ''Bacillus subtilis''.
 
 
 
* 5:00 – 5:15 T35, [[Tony Wilkinson]], Dept. of Chemistry, University of York, UK
 
** Structural and Interaction Studies of an Intercellular Complex Mediating Engulfment during Sporulation in ''B. subtilis''.
 
 
 
* 5:15 – 5:30 T36, [[Patrick Eichenberger]], Center for Genomics and Systems Biology, Dept. of Biology, New York University, New York, USA
 
** A Spatial and Temporal map of the ''Bacillus subtilis'' Spore Coat.
 
 
 
* 5:30 – 5:45 T37, Alex Ter Beek, Molecular Biology & Microbial Food Safety, University of Amsterdam, The Netherlands
 
** Live-cell imaging of aerobic bacteria: a tool to assess and model heterogeneous [[germination]] & outgrowth of ''Bacillus subtilis'' spores.
 
 
 
==Poster Session I==
 
* 5:45 – 7:45, Palazzo dei Congressi Sala Alba
 
 
 
=Tuesday, June 21, 2011– Morning=
 
 
 
==Pathogenic Sporeformers - Clostridia==
 
CHAIR: Mike Young
 
 
 
* 8:30 – 9:15, Neil Fairweather, Centre for Molecular Microbiology and Infection, Dept. of Life Sciences, Imperial College London, London, UK
 
** Keynote Lecture: The cell wall of ''Clostridium difficile'' – is variability a key to pathogenesis?
 
 
 
* 9:15 – 9:30 T38, [[Linc Sonenshein]], Tufts University School of Medicine, Boston, Massachusetts, USA
 
** Regulation of ''Clostridium difficile'' virulence.
 
 
 
* 9:30 – 9:45 T39, Zhen Zhang, Faculty of Veterinary Medicine, University of Helsinki, Finland
 
** A [[Two-component systems|Two-Component System]] Negatively Regulates Botulinum Neurotoxin Expression.
 
  
* 9:45 10:00 T40, Eric A. Johnson, University of Wisconsin, Madison, Wisconsin, USA
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* 8:30 8:55 Registration
** Identification, Purification and Characterization of Botulinum Neurotoxin BoNT/A Subtype Toxins.  
+
* 8:55 Welcome - Chancellors’ Building, room 1.12
  
* 10:00 – 10:15 T41, Stephen Melville, Dept. of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA
+
== Session 1 Regulation==
** Spatial and temporal linkage of type IV pili assembly and division septum formation in ''Clostridium perfringens''.
+
CHAIR:  David Leak
 +
* 09:00 [[Ciaran Condon]]
 +
** Suppression of the essential nature of RNase M16 ([[YqfG]]), required for 3' maturation of ''B. subtilis'' 16S ribosomal RNA, by deletion of [[rnr|RNase R]]
 +
* 09:15 [[Roland Hartmann]]
 +
** Function and regulation of two 6S RNAs in Bacillus subtilis
 +
* 09:30 [[Matthias Mack]]
 +
** A dual control mechanism synchronizes riboflavin and sulphur metabolism in ''Bacillus subtilis''
 +
* 09:45 Hermann Rath
 +
** A [[SigB]]-dependent antisense RNA affects osmotic induction of ''[[opuBA|opuB]]'' expression in ''Bacillus subtilis''
 +
* 10:00 Laura Teichmann
 +
** Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor [[GbsR]]
 +
* 10:15 Sylvain Durand
 +
** sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation
  
* 10:15 10:30 T42, Jon Marles-Wright, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK
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== 10:30 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer==
** Towards an understanding of the anatomy of Clostridial bacterial microcompartments.
 
  
==Pathogenic Sporeformers - ''Bacillus anthracis''==
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== Session 2 [[Cell division]]==
CHAIR: Olaf Schneewind
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CHAIR:  TBA
 +
* 11:00 [[Henrik Strahl]]
 +
** ''Bacillus subtilis'' does not form microscopically detectable cardiolipin domains
 +
* 11:15 Jeanine Rismondo
 +
** Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
 +
* 11:30 Edward de Koning
 +
** [[Divisome]] maturation in ''Bacillus subtilis'' single cells
 +
* 11:45 Seamus Holden
 +
** Treadmilling by [[FtsZ]] filaments drives ''Bacillus subtilis'' [[cell wall synthesis|peptidoglycan synthesis]] and bacterial [[cell division]]
 +
* 12:00 [[Dirk-Jan Scheffers]]
 +
** [[PbpB|PBP2B]] [[PASTA domains]] interact with [[DivIB]] to stabilize [[cell division]]
 +
* 12:15 Yongqiang Gao
 +
** [[Cell division]] in the cell wall-less bacterium ''Acholeplasma laidlawii''
  
* 11:00 – 11:15 T43, Theresa M. Koehler, Dept. Microbiol. and Molec. Genet., University of Texas Medical School, Houston, Texas, USA
 
** Modulation of the ''Bacillus anthracis'' Secretome.
 
  
* 11:15 11:30 T44, Susanne Pohl, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK
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== 12:30 14:30 Lunch and Poster Session 1==
** The secondary secretion pathway in ''Bacillus anthracis''.
 
  
* 11:30 – 11:45 T45, Agnès Fouet, Toxines et Pathogénie Bactériennes, Institut Pasteur, Paris, France
+
== Session 3 – Interesting Biology ==
** ''Bacillus anthracis'' virulence regulator AtxA mediates bicarbonate induction of toxin gene expression.  
+
CHAIR:  [[Colin Harwood]]
 +
* 14:30 [[Jörg Stülke]]
 +
** DNA topoisomerases in ''Bacillus subtilis'': A tale on mutants and suppressors
 +
* 14:45 Hannah Gaimster
 +
** Lethal depletion of essential cell envelope proteins can be rescued by slowing [[DNA replication]] in ''Bacillus subtilis''
 +
* 15:00 Alexandre Deloupy
 +
** Stochastic gene expression in Bacillus subtilis
 +
* 15:15 Sabine Schneider
 +
** Development of a reporter gene system to characterise [[riboswitch]] function and to identify [[riboswitch]] modulators by high-throughput screening
 +
* 15:30 [[Ken-ichi Yoshida]]
 +
** Rapid conjugative mobilization of a 100 kb segment of ''Bacillus subtilis'' chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
 +
* 15:45 Anna A. Toymentseva
 +
** Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element
  
* 11:45 – 12:00 T46, [[Colin Harwood]], Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle-upon-Tyne, UK
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==16:00 – 16:30 Tea and Coffee ==
** Are superoxide ions a key environmental signal for the ''Bacillus anthracis'' pathogenic life cycle?
 
 
 
=Tuesday, June 21, 2011– Morning=
 
 
 
==[[Transcription]] Regulation I==
 
CHAIR: Terry Koehler
 
 
 
* 2:00 – 2:15 T47, Kris Ann Baker, Dept. of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA
 
** Transcription anti-termination by a phosphorylated response regulator and cobalamin-dependent termination at a B12 [[riboswitch]] contribute to ethanolamine utilization in ''Enterococcus faecalis''.
 
 
 
* 2:15 – 2:30 T48, [[Harald Putzer]], Institut de Biologie Physico-Chimique, Paris, France
 
** The roles of [[RNases]] [[rny|Y]] and [[rnjA|J]] in mRNA metabolism in ''Bacillus subtilis''.
 
 
 
* 2:30 – 2:45 T49, Jean-Christophe Giard, Laboratoire de Microbiologie de l’Environnement, University of Caen, Caen, France
 
** First experimental genome-wide identification of [[ncRNA|small non-coding RNAs]] in the opportunistic pathogen ''Enterococcus faecalis'' V583.
 
 
 
* 2:45 – 3:00 T50, [[Peter Lewis]], School of Environmental and Life Sciences, University of Newcastle, Callaghan, Australia
 
** Structure/Function analysis of epsilon: A new subunit of Gram positive [[RNA polymerase|RNA polymerases]].
 
 
 
* 3:00 – 3:15 T51, Olivier Delumeau, INRA, Micalis Institute, Jouy-en-Josas, France
 
** The dynamic protein partnership of [[RNA polymerase]] in ''Bacillus subtilis''.
 
 
 
* 3:15 – 3:30 T52, [[Thorsten Mascher]], Department of Biology, Ludwig-Maximilians-University, Munich, Germany
 
** Extracytoplasmic function (ECF) [[sigma factors]] in gram-positive bacteria: Heading for the unknown.
 
 
 
==[[Transcription]] Regulation II==
 
CHAIR: [[Linc Sonenshein]]
 
 
 
* 4:00 –4:15 T53, Michael J. Federle, Dept. of Med. Chem. Pharmacognosy, The University of Illinois at Chicago, Chicago, Illinois, USA
 
** Rgg [[transcription factors]] are a new class of pheromone response effectors in streptococci.
 
 
 
* 4:15 – 4:30 T54, Rozenn Gardan, INRA UMR1319 Micalis, Jouy-en-Josas, France
 
** Rgg-associated small hydrophobic peptides: A new family of pheromones involved in [[quorum sensing]] in streptococci.
 
 
 
* 4:30 – 4:45 T55, Isabelle Poquet, Microbiologie de l’Alimentation au service de la Santé, UMR 1319 Micalis, Jouy-en-Josas, France
 
** ''Lactococcus lactis'' ZitR is a zinc responsive repressor active in low, non-toxic zinc concentrations ''in vivo''.
 
 
 
* 4:45 – 5:00 T56, Thomas Dubois, INRA, UMR1319 Micalis, Jouy-en-Josas, France
 
** The NprR quorum sensor is required for the saprophytic way of life of ''Bacillus cereus''.
 
 
 
* 5:00 – 5:15 T57, Boris R. Belitsky, Tufts University School of Medicine, Boston, Massachusetts, USA
 
** Multiple modes of DNA binding and regulation by ''Bacillus subtilis'' [[CodY]].
 
 
 
==Poster Session II==
 
* 5:30 – 7:30, Palazzo dei Congressi Sala Alba
 
 
 
=Wednesday, June 22, 2011– Morning=
 
 
 
==Pathogenesis II==
 
CHAIR: Agnes Fouet
 
 
 
* 8:30 – 8:45 T58, Hèléne Bierne, Institut Pasteur, Unité des Interactions Bactéries Cellules – Inserm, Paris, France
 
** ''Listeria monocytogenes'' hijacks the chromatin-remodeling machinery to modulate type III interferon responses.
 
 
 
* 8:45 – 9:00 T59, Jennifer Mitchell, University College Dublin, Dublin, Ireland
 
** CD36 is a receptor for the adherence of Gram positive pathogens to platelets.
 
 
 
* 9:00 – 9:15 T60, Marco Rinaldo Oggioni, University of Siena, Siena, Italy
 
** A single bacterium at the origin of invasive pneumococcal disease: macrophage clearance defines the bottleneck during the first hours of infection.
 
 
 
* 9:15 – 9:30 T61, Johannes Huebner, Division of Infectious Diseases, University Hospital Freiburg, Freiburg, Germany
 
** Genetic loci involved in surface carbohydrate production in Enterococci.
 
 
 
* 9:30 – 9:45 T62, Kimberly Kline, Dept. of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA
 
** Molecular requirements for localized secretion and sortase-assembled virulence factor biogenesis in ''Enterococcus faecalis''.
 
 
   
 
   
* 9:45 – 10:00 T63, Hailyn V. Nielsen, University of Washington School of Medicine, St. Louis, Missouri, USA
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==Session 4 – Antibiotics 1 ==
** Minor tip and base pilins EbpA and EbpB contribute to ''E. faecalis'' virulence in a murine model of foreign body-associated urinary tract infection.  
+
CHAIR:  [[Ulrike Mäder]]
 +
* 16:30 Carolin Kobras
 +
** Exploring the substrate specificity of the antimicrobial peptide resistance transporter [[BceA]]-[[BceB]] in ''Bacillus subtilis''
 +
* 16:45 Luiza P. Morawska
 +
** Preadaptation of ''Bacillus subtilis'' to mild osmostress contributes to increased antibiotic resistance
 +
* 17:00 Mary K. Phillips-Jones
 +
** Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
 +
* 17:15 Gabriela Henriques
 +
** Towards the understanding of the regulation of [[SppA]] by [[YteJ]] in Bacillus subtilis.
  
==[[Resistance against toxins/ antibiotics|Antimicrobial resistance]]==
+
== Free evening in Bath ==
CHAIR: [[Jan Maarten van Dijl]]
 
  
* 10:30 – 10:45 T64, Emma L. Denham, University Medical Center Groningen, Department of Medical Microbiology, Groningen, The Netherlands
+
= Wednesday 13th June =
** Unraveling the bactericidal mechanism of the glycopeptides sublancin 168.
 
  
*10:45 – 11:00 T65, Alexandra A. Roberts, School of Pharmacy, University of East Anglia, Norwich, UK
+
== Session 5 Biotechnology ==
** FosB is a bacillithiol-S-transferase that confers bacillithiol-dependent fosfomycin resistance on the Gram positive pathogen ''Staphylococcus aureus''.
+
CHAIR:  Anne Breüner
 +
* 9:00 Andreas Knapp
 +
** The spacer region in the 5´-UTR strongly affects recombinant protein production in ''Bacillus subtilis''
 +
* 9:15 Alexandria Holland
 +
** Investigating protein secretion in ''Geobacillus thermoglucosidasius''
 +
* 9:30 Matthew Styles
 +
** Engineering ''Parageobacillus'' for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
 +
* 9:45 Luca Longanesi
 +
** γ-PGA production through Consolidated Bioprocessing in engineered ''B. subtilis'' lab strains
 +
* 10:00 Matteo Cavaletti
 +
** Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
 +
* 10:15 Ioannis Mougiakos
 +
** Characterizing a thermostable Cas9 for bacterial genome editing and silencing
  
* 11:00 – 11:15 T66, [[Tarek Msadek]], Biology of Gram-positive Pathogens, Department of Microbiology, Institut Pasteur, Paris, France
+
== 10:15 - 10:45 Tea and Coffee ==
** The [[ABC transporters|ABCs]] of bacitracin and nisin resistance in ''Staphylococcus aureus''.
 
  
* 11:15 – 11:30 T67, Susanne Gebhard, Department of Biology, Ludwig-Maximilians University Munich, Munich, Germany
+
== Session 6 - [[Sporulation]] and development ==
** Co-evolution of and signaling by [[ABC transporters]] and [[two-component systems|two-component regulatory systems]] as [[Resistance against toxins/ antibiotics|resistance modules against antimicrobial peptides]] in Firmicutes bacteria.
+
CHAIR:  TBC
 
+
* 10:45 [[Imrich Barák]]
* 11:30 – 11:45 T68, Willem van Schaik, Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
+
** What we (don’t) know about the asymmetric septum in ''Bacillus subtilis''
** Comprehensive identification of genes required for resistance to β-lactam antibiotics in the nosocomial pathogen ''Enterococcus faecium''.
+
* 11:00 Munehiro Asally
 
+
** Quality monitoring during [[sporulation]] in ''B. subtilis''  
* 11:45 – 12:00 T69, Mary K. Phillips-Jones, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK
+
* 11:15 [[Ilka Bischofs]]
** ''In vitro'' activation and inhibition of the intact quorum membrane sensor FsrC involved in virulence in ''Enterococcus faecalis'' V583
+
** Phenotypic memory links different stages of the ''B. subtilis'' life cycle
 
+
* 11:30 [[Akos Kovacs]]
=Wednesday, June 22, 2011– Afternoon=
+
** Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
 
+
* 11:45 [[Sven Halbedel]]  
==Pathogenesis III==
+
** Novel ''[[gpsB]]'' suppressor genes contributing to regulatory proteolysis and ''cell division''
CHAIR: Johannes Huebner
+
* 12:00 Sofia Arnaouteli
 
+
** Exploring the role of pulcherrimin in ''Bacillus subtilis'' [[biofilm formation]]
* 2:00 – 2:15 T70, Breck A. Duerkop, Department of Immunology, University of Texas, Dallas, Texas, USA
+
* 12:15 Karin Bjerre
** Bacteriophage production by ''Enterococcus faecalis'' in the mammalian intestine.
+
** Investigating of ''Bacillus subtilis'' and ''Bacillus amyloliquefaciens'' spores and vegetative cells in fecal samples from pigs
 
 
* 2:15 – 2:30 T71, Renata Matos, ITQB, Oeiras, Portugal; Institut Micalis, INRA, Jouy-en-Josas, France; Universidad Complutense de Madrid, Spain
 
** ''Enterococcus faecalis'' V583 prophages are induced by low concentrations of antibiotic.
 
 
 
* 2:30 – 2:45 T72, Pascale S. Guiton, Dept. of Mol. Microbiol. & Microbial Pathogenesis, Washington University, St. Louis, Missouri, USA
 
** Characterization of the host response to ''Enterococcus faecalis'' mediated catheter-associated urinary tract infection.
 
 
 
* 2:45 – 3:00 T73, Ravi P.N. Mishra, Novartis Vaccines and Diagnostics, Siena, Italy
 
** Ferric Hydroxamate-binding Lipoprotein FhuD2 protects against ''Staphylococcus aureus'' infection.
 
 
 
==Pathogenesis IV: Streptococci==
 
CHAIR: Paul Sullam
 
 
 
* 3:30 – 3:45 T74, Heaven Oliver-Kozup, Dept. Microbiol., Immunol. & Cell Biol., West Virginia University, Morgantown, West Virginia, USA
 
** Targeted binding of the surface adhesion Sel1 to a spliced variant of cellular fibronectin expressed in wounded tissue.
 
 
 
* 3:45 – 4:00 T75, Kathryn M. Gold, Dept. of Cell Biology & Molecular Genetics, University of Maryland, College Park, Maryland, USA
 
** Characterization of the TrxSR [[two-component systems|Two-Component Signal Transduction System]] that Activates Virulence in ''Streptococcus pyogenes''.
 
 
 
* 4:00 – 4:15 T76, Vijay Pancholi, Department of Pathology, The Ohio State University, Columbus, Ohio, USA
 
** A novel transcriptional regulatory role of [[sdhA|SDH]]/[[gapA|GAPDH]] in ''Streptococcus pyogenes'' [[metabolism]] and virulence.
 
 
 
* 4:15 – 4:30 T77, Sean D. Reid, Dept. Microbiol. & Immunol., Wake Forest University, Winston-Salem, North Carolina, USA
 
** Insights into the regulation of Group A Streptococcal [[biofilm formation]] and dispersal and the impact on disease severity.
 
 
 
* 4:30 – 4:45 T78, Ravin Seepersaud, Division of Infectious Disease, University of California, San Francisco, California, USA
 
** The accessory Sec protein Asp2 is required for both the optimal glycosylation and transport of GspB, the serine rich repeat glycoprotein adhesion of ''Streptococcus gordonii''.
 
 
 
* 4:45 – 5:00 T79, Françoise Rul, INRA, Micalis Institute, Jouy-en-Josas, France
 
** The proteomic signature of ''Streptococcus thermophilus'' in the digestive environment provides clues to lactic acid bacteria/host interactions.
 
 
 
* 5:00 – 5:15 T80, Philippe Glaser, Laboratoire Evolution et Génomique Bactériennes, Institut Pasteur, Paris, France
 
** Emergence of a ''Streptococcus agalactiae'' lineage hypervirulent in fish by reductive evolution.
 
 
 
* 5:15 – 5:30 T81, Shaynoor Dramsi, Institut Pasteur, Unité de Biologie des Bactéries Pathogènes à Gram-Positif, Paris, France
 
** Role of ''Streptococcus gallolyticus'' Pil1 pilus in endocarditis.
 
 
 
==Reception and Banquet - 6:30 – 9:30  – Grand Hotel & La Pace==
 
 
 
=Thursday, June 23, 2011– Morning=
 
 
 
==Stress I==
 
CHAIR: [[Erhard Bremer]]
 
 
 
* 8:30 – 8:45 T82, Terry A. Krulwich, Dept. Pharmacol. Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, USA
 
** In accord with the “no free lunch” principle, adaptations of alkaliphilc ''Bacillus'' that support constitutive readiness for an alkali challenge reduce fitness near neutral pH.
 
 
 
* 8:45 – 9:00 T83, Masahiro Ito, Graduate School of Life Science, Toyo University, Oura-gun, Gunma, Japan
 
** A novel K+-stimulated flagellar motor from alkaliphilic ''Bacillus''.
 
 
 
* 9:00 – 9:15 T84, [[Jan Maarten van Dijl]], University Medical Center Groningen, Dept.of Medical Microbiology, Groningen, The Netherlands
 
** Intrinsic salt-sensitivity of minimal [[TatAC]] protein translocases in Gram-positive bacteria.
 
 
* 9:15 – 9:30 T85, Veronique Broussolle, INRA, Université d’Avignon et des Pays de Vaucluse, Avignon, France
 
** [[DEAD-box RNA helicases|RNA helicases]] are involved in the cold adaptation of ''Bacillus cereus'' ATCC 14579.
 
  
* 9:30 – 9:45 T86, Geremy Clair, INRA, Université d’Avignon et des Pays de Vaucluse, Avignon, France
+
==12:30 – 14:30 Lunch and Poster Session 2 ==
** ''Bacillus cereus'' responds to low extracellular oxidoreduction potential by readjusting its proteome and secretome.
 
  
* 9:45 10:00 T87, [[Ulrike Mäder]], Ernst-Moritz-Arndt-University, Greifswald, Germany
+
==Session 7 Antibiotics 2 ==
** Whole-transcriptome analysis of ''Bacillus subtilis'' under various environmental conditions.
+
CHAIR: [[Kevin Devine]]
 +
* 14:30 Auke J. van Heel
 +
** BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
 +
* 14:45 Amanda Y. van Tilburg
 +
** ''Bacillus subtilis'' as heterologous production host for lantibiotics
 +
* 15:00 Nina Lautenschlaeger
 +
** A novel heterologous whole-cell biosensor in ''Bacillus subtilis'' for the comprehensive detection of b-lactam antibiotics
 +
* 15:15 Marjorie Gibbon
 +
** Towards understanding signalling between the bacitracin resistance transporter [[BceA]]-[[BceB]] and histidine kinase [[BceS]] of ''Bacillus subtilis''
  
==Stress II==
+
== 15:30 – 16:00 Tea and Coffee ==
CHAIR: Terry Krulwich
 
  
* 10:30 10:45 T88, Axel Hartke, Lab. Microbiologie de l’Environnement, Université de Caen, Caen, France
+
== Session 8 – Cereus Group ==
** The oxidative stress response of Enterococci: Connection to virulence and antibiotic resistance.
+
CHAIR:  [[Cinzia Calvio]]
 +
* 16:00 Monika Ehling-Schulz
 +
** ''Bacillus cereus'', a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
 +
* 16:15 Nick Waterfield
 +
** ''Bacillus cereus'' G9241 to anthrax and back again
 +
* 16:30 Ludivine Rousset
 +
** Oligotrophy induces phenotypic diversification of ''Bacillus cereus'' AH187
 +
* 16:45 Jan Maarten van Dijl
 +
** Can ''Bacillus thuringiensis'' and other microorganisms isolated from chronic wounds ‘pacify’ ''Staphylococcus aureus''?
  
* 10:45 – 11:00 T89, Matthieu Jules, INRA, Micalis Institute, Jouy-en-Josas, France
+
== 17:00 Closing Remarks==
** Multi-omics, multi-laboratory study unravels ''Bacillus'' dynamic responses to environmental shifts.
 
  
* 11:00 – 11:15 T90, [[Erhard Bremer]], Microbiology, Philipps University of Marburg, Marburg, Germany
+
== 19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs ==
** Regulation of the synthesis of the osmoprotectant glycine betaine in ''B. subtilis'': Induction by choline and repression by a chemical chaperone.
 
  
* 11:15 – 11:30 T91, Mamta Rawat, California State University-Fresno, California, USA
 
** Bacillithiol dependent detoxification in ''Staphylococcus aureus''.
 
  
* 11:30 – 11:45 T92, Vanessa Khemici, Centre National de la Recherche Scientifique, Université de Toulouse, Toulouse, France
+
= END OF MEETING =
** DNA replication stress triggers competence for genetic transformation in ''Streptococcus pneumoniae''.
 
  
==Closing remarks==
 
  
 
=Back to [[Main Page|SubtiWiki]]=
 
=Back to [[Main Page|SubtiWiki]]=

Latest revision as of 15:38, 4 June 2018

Tuesday 12th June

  • 8:30 – 8:55 Registration
  • 8:55 Welcome - Chancellors’ Building, room 1.12

Session 1 Regulation

CHAIR: David Leak

  • 09:00 Ciaran Condon
    • Suppression of the essential nature of RNase M16 (YqfG), required for 3' maturation of B. subtilis 16S ribosomal RNA, by deletion of RNase R
  • 09:15 Roland Hartmann
    • Function and regulation of two 6S RNAs in Bacillus subtilis
  • 09:30 Matthias Mack
    • A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis
  • 09:45 Hermann Rath
    • A SigB-dependent antisense RNA affects osmotic induction of opuB expression in Bacillus subtilis
  • 10:00 Laura Teichmann
    • Suppressor analysis illuminates the structure/function relationship of the glycine betaine synthesis repressor GbsR
  • 10:15 Sylvain Durand
    • sRNA-mediated activation of gene expression by inhibition of 5’-3’exonucleolytic mRNA degradation

10:30 – 11:00 Tea and Coffee - Chancellors’ Building, ground floor foyer

Session 2 Cell division

CHAIR: TBA

  • 11:00 Henrik Strahl
    • Bacillus subtilis does not form microscopically detectable cardiolipin domains
  • 11:15 Jeanine Rismondo
    • Discovery of genes required for lipoteichoic acid glycosylation predicts two distinct mechanism for wall teichoic acid glycosylation
  • 11:30 Edward de Koning
    • Divisome maturation in Bacillus subtilis single cells
  • 11:45 Seamus Holden
  • 12:00 Dirk-Jan Scheffers
  • 12:15 Yongqiang Gao
    • Cell division in the cell wall-less bacterium Acholeplasma laidlawii


12:30 – 14:30 Lunch and Poster Session 1

Session 3 – Interesting Biology

CHAIR: Colin Harwood

  • 14:30 Jörg Stülke
    • DNA topoisomerases in Bacillus subtilis: A tale on mutants and suppressors
  • 14:45 Hannah Gaimster
    • Lethal depletion of essential cell envelope proteins can be rescued by slowing DNA replication in Bacillus subtilis
  • 15:00 Alexandre Deloupy
    • Stochastic gene expression in Bacillus subtilis
  • 15:15 Sabine Schneider
    • Development of a reporter gene system to characterise riboswitch function and to identify riboswitch modulators by high-throughput screening
  • 15:30 Ken-ichi Yoshida
    • Rapid conjugative mobilization of a 100 kb segment of Bacillus subtilis chromosomal DNA is mediated by a helper plasmid with no ability for self-transfer
  • 15:45 Anna A. Toymentseva
    • Mobilization and transfer of plasmids and chromosomal DNA mediated by optimized ICEBs1 conjugative element

16:00 – 16:30 Tea and Coffee

Session 4 – Antibiotics 1

CHAIR: Ulrike Mäder

  • 16:30 Carolin Kobras
    • Exploring the substrate specificity of the antimicrobial peptide resistance transporter BceA-BceB in Bacillus subtilis
  • 16:45 Luiza P. Morawska
    • Preadaptation of Bacillus subtilis to mild osmostress contributes to increased antibiotic resistance
  • 17:00 Mary K. Phillips-Jones
    • Characterisation of the VanA-type VanS histidine kinase involved in glycopeptide resistance in Gram-positive bacteria and its ligand interactions
  • 17:15 Gabriela Henriques
    • Towards the understanding of the regulation of SppA by YteJ in Bacillus subtilis.

Free evening in Bath

Wednesday 13th June

Session 5 Biotechnology

CHAIR: Anne Breüner

  • 9:00 Andreas Knapp
    • The spacer region in the 5´-UTR strongly affects recombinant protein production in Bacillus subtilis
  • 9:15 Alexandria Holland
    • Investigating protein secretion in Geobacillus thermoglucosidasius
  • 9:30 Matthew Styles
    • Engineering Parageobacillus for the Production of Terpenes: Building Better Chassis Organisms for Industrial Biotechnology
  • 9:45 Luca Longanesi
    • γ-PGA production through Consolidated Bioprocessing in engineered B. subtilis lab strains
  • 10:00 Matteo Cavaletti
    • Optimization of γ-PGA biosynthesis supported by synthetic biology and metabolic engineering strategies
  • 10:15 Ioannis Mougiakos
    • Characterizing a thermostable Cas9 for bacterial genome editing and silencing

10:15 - 10:45 Tea and Coffee

Session 6 - Sporulation and development

CHAIR: TBC

  • 10:45 Imrich Barák
    • What we (don’t) know about the asymmetric septum in Bacillus subtilis
  • 11:00 Munehiro Asally
  • 11:15 Ilka Bischofs
    • Phenotypic memory links different stages of the B. subtilis life cycle
  • 11:30 Akos Kovacs
    • Cheating promotes evolution of hyper-cooperators by shifting phenotypic heterogeneity in biofilms
  • 11:45 Sven Halbedel
    • Novel gpsB suppressor genes contributing to regulatory proteolysis and cell division
  • 12:00 Sofia Arnaouteli
  • 12:15 Karin Bjerre
    • Investigating of Bacillus subtilis and Bacillus amyloliquefaciens spores and vegetative cells in fecal samples from pigs

12:30 – 14:30 Lunch and Poster Session 2

Session 7 – Antibiotics 2

CHAIR: Kevin Devine

  • 14:30 Auke J. van Heel
    • BAGEL4: A user-friendly web server to mine RiPPs and bacteriocins
  • 14:45 Amanda Y. van Tilburg
    • Bacillus subtilis as heterologous production host for lantibiotics
  • 15:00 Nina Lautenschlaeger
    • A novel heterologous whole-cell biosensor in Bacillus subtilis for the comprehensive detection of b-lactam antibiotics
  • 15:15 Marjorie Gibbon
    • Towards understanding signalling between the bacitracin resistance transporter BceA-BceB and histidine kinase BceS of Bacillus subtilis

15:30 – 16:00 Tea and Coffee

Session 8 – Cereus Group

CHAIR: Cinzia Calvio

  • 16:00 Monika Ehling-Schulz
    • Bacillus cereus, a multifaceted pathogen: The challenge of discriminating high and low enteropathogenic strains
  • 16:15 Nick Waterfield
    • Bacillus cereus G9241 – to anthrax and back again
  • 16:30 Ludivine Rousset
    • Oligotrophy induces phenotypic diversification of Bacillus cereus AH187
  • 16:45 Jan Maarten van Dijl
    • Can Bacillus thuringiensis and other microorganisms isolated from chronic wounds ‘pacify’ Staphylococcus aureus?

17:00 Closing Remarks

19:00 – 23:00 Social event at The Terrace, The Roman Baths, generously supported by BACIP – to include the prize giving for best posters and talks from PhD/Postdocs

END OF MEETING

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