iolW

iolW
168

scyllo-inositol dehydrogenase, general stress protein

Locus
BSU_33530
Molecular weight
39.95 kDa
Isoelectric point
5.46
Protein length
358 aaSequenceBlast
Gene length
1077 bpSequenceBlast
Function
utilization of scyllo-inosose
Product
scyllo-inositol dehydrogenase
Essential
no
Synonyms
iolW, yvaA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0673 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,444,329  3,445,405
The protein
Catalyzed reaction/ biological activity
NADPH-dependent conversion of scyllo-inosose to scyllo-inositol PubMed
NADP+ + scyllo-inositol --> H+ + NADPH + scyllo-inosose (according to UniProt)
Protein family
Gfo/Idh/MocA family (according to UniProt)
Cofactors
NADP+ PubMed
Structure
3GFG (PDB)
O32223 (AlphaFold)
Paralogous protein(s)
IolU, IolG, YrbE, IolX, YfiI, NtdC, YteT
Expression and Regulation
Operons
Genes
iolW
Description
PubMed
Regulation
induced by stress (SigB) PubMed
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
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iolW

2025-03-16 17:55:22

Bzhu

116

f7d2c023074100be48758159f46bfe56fa945673

9AD1D5A966A01BF716D22ECF21595BAF992727ED

Biological materials
Mutant
MGNA-A443 (iolU::erm), available at the NBRP B. subtilis, Japan
BKE33530 (iolW::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACAGAAGTATATACCCTC,  downstream forward: _UP4_TAAAACAAAAGCCTCCCCAA
BKK33530 (iolW::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACAGAAGTATATACCCTC,  downstream forward: _UP4_TAAAACAAAAGCCTCCCCAA
References
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7DFE74C751A67CCC84579D52005E1399B0A10166

Page visits: 4481

Time of last update: 2025-04-03 22:45:32

Author of last update: Melvin.boenninger