holA

holA
168

DNA polymerase III, delta subunit, part of the clamp-loader complex and the replisome

Locus
BSU_25560
Molecular weight
40.35 kDa
Isoelectric point
6.23
Protein length
347 aaSequenceBlast
Gene length
1044 bpSequenceBlast
Function
DNA replication
Product
DNA polymerase III, delta subunit
Essential
yes
E.C.
2.7.7.7
Synonyms
holA, yqeN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1466 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,636,096 → 2,637,139
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
required for bacteriophage SPP1 replication PubMed
Domains
domain I: aa 1 - 143, RecA-like fold PubMed
domain II: aa 144 - 214, four alpha helices PubMed
domain III: aa 215 - 339, seven alpha helices PubMed
Structure
3ZH9 (PDB) PubMed
P54459 (AlphaFold)
Localization
Nucleoid (Mid-cell) PubMed
Expression and Regulation
Operons
Genes
holA
Description
PubMed
Open in new tab

holA

2025-03-17 19:19:26

Jstuelk

94

d4f1afade58cef408cd2b5f67f8d5ec44963b288

5386793F90265B36A6A6C1C4BD1A02A884F43AE2

References
Loading

CE70B471811371D454A74F67279974BF264205C2

Page visits: 5084

Time of last update: 2025-04-22 23:44:04

Author of last update: Jstuelk