degQ

degQ
168

stimulates production of degradative enzymes and of extracellular poly-gamma-glutamate, stimulates phosphorylation of DegU by DegS, gene is not expressed in the lab strain 168 due to promoter down mutation in the -10 region (T - 10 ---> C)

Locus
BSU_31720
Molecular weight
5.41 kDa
Isoelectric point
6.54
Protein length
Gene length
Function
regulation of exoenzyme synthesis
Product
pleiotropic regulator
Essential
no
Synonyms
degQ, sacQ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
3,257,092  3,257,232
Phenotypes of a mutant
loss of poly-gamma-glutamate production PubMed, no synthesis of nonribosomal peptides iturin A and plipastatin PubMed1 PubMed2, reduced synthesis of degradative enzymes PubMed, increased genetic competence PubMed
The protein
Catalyzed reaction/ biological activity
stimulates autophosphorylation of DegS PubMed
Protein family
degQ family (single member, according to UniProt)
Structure
Expression and Regulation
Operons
Genes
Description
Regulation
controlled by DegU PubMed
Regulatory mechanism
ComA: activation, PubMed, in comA regulon
DegU: activation, PubMed, in degU regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the gene is not expressed in the lab strain 168 due to promoter down mutation in the -10 region (T - 10 ---> C) PubMed
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degQ

2025-02-16 06:25:04

ghost

74

295bf9607a2c7fe56cbc482802ec9059c7e79c09

FB5DBB850B570B548EC4A9708026B89C05AD807D

Biological materials
Mutant
QB4851 (cat), available in Jörg Stülke's lab
BKE31720 (degQ::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCGTTTCCACACTCCTTT,  downstream forward: _UP4_TGAAAAAGACTTGGAAACAA
BKK31720 (degQ::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATCGTTTCCACACTCCTTT,  downstream forward: _UP4_TGAAAAAGACTTGGAAACAA
References
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Time of last update: 2025-04-10 01:31:42

Author of last update: Jstuelk