yneI

yneI
168

two-component response regulator

Locus
BSU_17940
Molecular weight
13.40 kDa
Isoelectric point
6.95
Protein length
120 aaSequenceBlast
Gene length
363 bpSequenceBlast
Function
unknown
Product
two-component response regulator
Essential
no
Synonyms
yneI, yoxH, ccdB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4753 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,924,030  1,924,392
The protein
Domains
Response regulatory domain (aa 3-118) (according to UniProt)
Structure
1TMY (PDB) (CheY from Thermotoga maritima, 57% identity)
P45709 (AlphaFold)
Paralogous protein(s)
CheY
Expression and Regulation
Operons
Genes
ccdA-yneI-yneJ
Description
PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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ccdA→yneJ

2025-03-08 17:16:27

ghost

64

6d9fa6a1bf651321d3fe17f03c412d0f1d9ef50f

4B829C2A057C50FF5C196DC8FA05ABACC56DE328

Biological materials
Mutant
BKE17940 (yneI::ermC) (available at the BGSC and in Jörg Stülke's lab) PubMed
GP1866 (yneI::ermC) (available in Jörg Stülke's lab)
BKE17940 (yneI::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTCCCCTCCAACAATC,  downstream forward: _UP4_TAAAGTCATTTCTTTTCAAA
BKK17940 (yneI::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTCCCCTCCAACAATC,  downstream forward: _UP4_TAAAGTCATTTCTTTTCAAA
References
Schiött T, Hederstedt L Efficient spore synthesis in Bacillus subtilis depends on the CcdA protein. Journal of bacteriology. 2000 May; 182(10):2845-54. . PMID:10781554
Fabret C, Feher VA, Hoch JA Two-component signal transduction in Bacillus subtilis: how one organism sees its world. Journal of bacteriology. 1999 Apr; 181(7):1975-83. . PMID:10094672
Schiött T, von Wachenfeldt C, Hederstedt L Identification and characterization of the ccdA gene, required for cytochrome c synthesis in Bacillus subtilis. Journal of bacteriology. 1997 Mar; 179(6):1962-73. . PMID:9068642

AE823A0A652509787EA032F122E59F3C3645385F

Page visits: 2122

Time of last update: 2025-04-10 03:19:56

Author of last update: Melvin.boenninger