yodF
168

similar to amino acid permease

Locus

BSU_19580

Molecular weight

53.60 kDa

Isoelectric point

9.68

Protein length

496 aaSequenceBlast

Gene length

1491 bpSequenceBlast

Function

unknown

Product

unknown

Essential

Synonyms

yodF

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0591 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

2,130,377 2,131,867

The protein

Catalyzed reaction/ biological activity

in some database, the protein is annotated as being similar to proline permease, however, it is not involved in proline transport PubMed

Protein family

sodium:solute symporter (SSF) (TC 2.A.21) family (according to UniProt)

Structure

O34745 (AlphaFold)

Paralogous protein(s)

YhjB

Localization

membrane PubMed

Expression and Regulation

Operons

Genes

yoyD-yodF

Description

PubMed

Regulation

expression during spore germination is strongly reduced under conditions of osmotic stress PubMed

Regulatory mechanism

TnrA: repression, PubMed, in tnrA regulon

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Biological materials

Mutant

MGNA-B437 (yodF::erm), available at the NBRP B. subtilis, Japan

GP1887 ΔyodF::kan, available in Jörg Stülke's lab PubMed

GP3569 ΔyodF::phleo, available in Jörg Stülke's lab

GP3570 ΔyodF::cat, available in Jörg Stülke's lab

BKE19580 (yodF::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AAGTGCAGTCAGATTCCCTT, downstream forward: _UP4_TAAAAAAACCATACGCGGCA

BKK19580 (yodF::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_AAGTGCAGTCAGATTCCCTT, downstream forward: _UP4_TAAAAAAACCATACGCGGCA

References

Mirouze N, Bidnenko E, Noirot P, Auger S Genome-wide mapping of TnrA-binding sites provides new insights into the TnrA regulon in Bacillus subtilis. MicrobiologyOpen. 2015 Jun; 4(3):423-35. doi:10.1002/mbo3.249. PMID:25755103

Zaprasis A, Hoffmann T, Stannek L, Gunka K, Commichau FM, Bremer E The γ-aminobutyrate permease GabP serves as the third proline transporter of Bacillus subtilis. Journal of bacteriology. 2014 Feb; 196(3):515-26. doi:10.1128/JB.01128-13. PMID:24142252

Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis. Science (New York, N.Y.). 2012 Mar 02; 335(6072):1103-6. doi:10.1126/science.1206848. PMID:22383849

Hahne H, Wolff S, Hecker M, Becher D From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics. 2008 Oct; 8(19):4123-36. doi:10.1002/pmic.200800258. PMID:18763711

Yoshida K, Yamaguchi H, Kinehara M, Ohki YH, Nakaura Y, Fujita Y Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box. Molecular microbiology. 2003 Jul; 49(1):157-65. . PMID:12823818

Mäder U, Homuth G, Scharf C, Büttner K, Bode R, Hecker M Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability. Journal of bacteriology. 2002 Aug; 184(15):4288-95. . PMID:12107147

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Time of last update: 2025-04-06 06:05:58

Author of last update: MBenda

yodF 168

yodF
168