rpsD

rpsD
168

ribosomal protein uS4

Locus
BSU_29660
Molecular weight
22.69 kDa
Isoelectric point
10.24
Protein length
Gene length
Function
translation
Product
ribosomal protein S4 (uS4)
Essential
yes
Synonyms
rpsD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0522 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,035,730  3,036,332
Phenotypes of a mutant
essential PubMed
The protein
Protein family
S4 RNA-binding domain superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
universal ribosomal protein uS4 family (single member, according to UniProt)
S4 RNA-binding domain (aa 92-155) (according to UniProt)
Structure
1C06 (PDB) (Geobacillus stearothermophilus)
Expression and Regulation
Operons
Genes
Description
Regulation
autorepression of rpsD expression upon binding of excess RpsD to a RNA switch in the untranslated region of the rpsD mRNA PubMed
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
stringent response: negative regulation, in stringent response
RpsD: autorepression, PubMed, in rpsD regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of rpsD PubMed
the RNA switch RNA is degraded by RNase Y PubMed
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rpsD

2025-02-26 01:35:46

Jstuelk

77

52079A1F3A15425C8CCFFBF2F6BA2A9F8034F778

0D5D0DD6F002440DF27B5EB7D3A64075B74C9A1F

References
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Time of last update: 2025-04-10 01:40:07

Author of last update: Jstuelk