YugO

• Description: putative potassium channel protein
  
  

Gene name	yugO
Synonyms
Essential	no
Product	putative potassium channel protein
Function	unknown
Gene expression levels in SubtiExpress: yugO
Metabolic function and regulation of this protein in SubtiPathways: YugO
MW, pI	37 kDa, 7.091
Gene length, protein length	984 bp, 328 aa
Immediate neighbours	mstX, yugN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), biofilm formation, membrane proteins

This gene is a member of the following regulons

SinR regulon

The gene

Basic information

• Locus tag: BSU31322

Phenotypes of a mutant

• reduced biofilm formation (can be suppressed by inactivation of sinR) PubMed

Database entries

• BsubCyc: BSU31322

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • contains a RCK_N domain (according to UniProt, [2])

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU31322

• Structure:

• UniProt: Q795M8

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mstX-yugO PubMed

• Expression browser: yugO PubMed

• Sigma factor:

• Regulation:
  • repressed by SinR PubMed

• Regulatory mechanism:
  • SinR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:
  • TMB92 (yugO::tet), available in Erhard Bremer's and Jörg Stülke's labs

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Matthew E Lundberg, Eric C Becker, Senyon Choe
MstX and a putative potassium channel facilitate biofilm formation in Bacillus subtilis.
PLoS One: 2013, 8(5);e60993
[PubMed:23737939] [WorldCat.org] [DOI] (I e)