Difference between revisions of "CotU"
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17670 cotU] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17670 cotU] | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=CotU CotU] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 6.315 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 6.315 | ||
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<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:cotU_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:cotU_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17670]] |
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
{{SubtiWiki regulon|[[GerE regulon]]}}, | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
| − | {{SubtiWiki regulon|[[GerR regulon]]}} | + | {{SubtiWiki regulon|[[GerR regulon]]}}, |
| + | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
=The gene= | =The gene= | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17670&redirect=T BSU17670] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** outer spore coat, localization depends on [[CotE]] {{PubMed|22171814}} | ||
** the [[CotC]]-[[CotU]] complex assembles around the forming spore {{PubMed|18065538}} | ** the [[CotC]]-[[CotU]] complex assembles around the forming spore {{PubMed|18065538}} | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17670&redirect=T BSU17670] | ||
* '''Structure:''' | * '''Structure:''' | ||
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''cotU'' {{PubMed|22383849}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 cotU] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotU_1901117_1901377_-1 cotU] {{PubMed|22383849}} | ||
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=References= | =References= | ||
| − | <pubmed>18065538,12562816, 20023017,20435725 </pubmed> | + | <pubmed>18065538,12562816, 20023017,20435725 22171814</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Latest revision as of 13:50, 6 April 2015
- Description: spore coat protein
| Gene name | cotU |
| Synonyms | ynzH |
| Essential | no |
| Product | spore coat protein |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotU | |
| Interactions involving this protein in SubtInteract: CotU | |
| MW, pI | 11 kDa, 6.315 |
| Gene length, protein length | 258 bp, 86 aa |
| Immediate neighbours | yncF, ynzJ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
GerE regulon, GerR regulon, SigK regulon
The gene
Basic information
- Locus tag: BSU17670
Phenotypes of a mutant
Database entries
- BsubCyc: BSU17670
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU17670
- Structure:
- UniProt: O31802
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotU PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Giuseppina Cangiano, Antonio Mazzone, Loredana Baccigalupi, Rachele Isticato, Patrick Eichenberger, Maurilio De Felice, Ezio Ricca
Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis.
J Bacteriol: 2010, 192(13);3406-13
[PubMed:20435725]
[WorldCat.org]
[DOI]
(I p)
Rachele Isticato, Assunta Pelosi, Maurilio De Felice, Ezio Ricca
CotE binds to CotC and CotU and mediates their interaction during spore coat formation in Bacillus subtilis.
J Bacteriol: 2010, 192(4);949-54
[PubMed:20023017]
[WorldCat.org]
[DOI]
(I p)
Rachele Isticato, Assunta Pelosi, Rita Zilhão, Loredana Baccigalupi, Adriano O Henriques, Maurilio De Felice, Ezio Ricca
CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2008, 190(4);1267-75
[PubMed:18065538]
[WorldCat.org]
[DOI]
(I p)
Erh-Min Lai, Nikhil D Phadke, Maureen T Kachman, Rebecca Giorno, Santiago Vazquez, Jenny A Vazquez, Janine R Maddock, Adam Driks
Proteomic analysis of the spore coats of Bacillus subtilis and Bacillus anthracis.
J Bacteriol: 2003, 185(4);1443-54
[PubMed:12562816]
[WorldCat.org]
[DOI]
(P p)
