Difference between revisions of "BrnQ"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[transporters/ other]]}}, | {{SubtiWiki category|[[transporters/ other]]}}, | ||
| − | {{SubtiWiki category|[[biosynthesis/ acquisition | + | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}} |
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * no phenotype for the single mutant, the triple ''[[bcaP]] [[brnQ]] [[braB]]'' mutant is strongly impaired in the transport of isoleucine and valine at low concentrations {{PubMed|25645558}} | ||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** high affinity uptake of isoleucine and valine {{PubMed|25645558}} | ||
* '''Protein family:''' branched chain amino acid transporter family (according to Swiss-Prot) | * '''Protein family:''' branched chain amino acid transporter family (according to Swiss-Prot) | ||
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=References= | =References= | ||
| − | <pubmed> 9287000 </pubmed> | + | <pubmed> 9287000 25645558</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:47, 4 February 2015
- Description: branched-chain amino acid transporter
| Gene name | brnQ |
| Synonyms | yrdJ |
| Essential | no |
| Product | branched-chain amino acid transporter |
| Function | uptake of branched-chain amino acids |
| Gene expression levels in SubtiExpress: brnQ | |
| Metabolic function and regulation of this protein in SubtiPathways: brnQ | |
| MW, pI | 46 kDa, 9.777 |
| Gene length, protein length | 1320 bp, 440 aa |
| Immediate neighbours | yrdK, azlD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transporters/ other, biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU26690
Phenotypes of a mutant
- no phenotype for the single mutant, the triple bcaP brnQ braB mutant is strongly impaired in the transport of isoleucine and valine at low concentrations PubMed
Database entries
- BsubCyc: BSU26690
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- high affinity uptake of isoleucine and valine PubMed
- Protein family: branched chain amino acid transporter family (according to Swiss-Prot)
- Paralogous protein(s): BraB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU26690
- Structure:
- UniProt: P94499
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris R Belitsky
Role of branched-chain amino acid transport in Bacillus subtilis CodY activity.
J Bacteriol: 2015, 197(8);1330-8
[PubMed:25645558]
[WorldCat.org]
[DOI]
(I p)
B R Belitsky, M C Gustafsson, A L Sonenshein, C Von Wachenfeldt
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.
J Bacteriol: 1997, 179(17);5448-57
[PubMed:9287000]
[WorldCat.org]
[DOI]
(P p)
