moaA

moaA
168

molybdopterin precursor biosynthesis

Locus
BSU_36700
Molecular weight
38.39 kDa
Isoelectric point
9.28
Protein length
341 aaSequenceBlast
Gene length
1026 bpSequenceBlast
Function
nitrate respiration
Product
unknown
Essential
no
Synonyms
moaA, narA, narAB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2896 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,772,325  3,773,350
The protein
Catalyzed reaction/ biological activity
involved in the first step of molybdenum cofactor biosynthesis (together with YdiG)
AH2 + GTP + S-adenosyl-L-methionine --> (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H+ + L-methionine (according to UniProt)
Protein family
Radical SAM superfamily (according to UniProt)
Cofactors
Fe-S cluster PubMed
S-adenosyl methionine (according to UniProt)
Structure
1TV7 (PDB) (from Staphylococcus aureus, 49% identity) PubMed
P39757 (AlphaFold)
Expression and Regulation
Operons
Genes
fdhD-moaA
Description
PubMed
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fdhD→moaA

2025-04-07 03:21:31

Jstuelk

74

410b8239829f01425078c1591b355048857e9ded

6EF51E744DA5CB2F4D91D3A55A711AA8E13DA700

Biological materials
Mutant
BKE36700 (moaA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGTAATCATAGCTACAGCCC,  downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT
BKK36700 (moaA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGTAATCATAGCTACAGCCC,  downstream forward: _UP4_TAATTTGAAGTCAAAAGCTT
References
Reviews
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Original Publications
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19EB8E7CBC0E8D7A6429ADFFF93D1F71EFE3FF11

Page visits: 2325

Time of last update: 2025-04-09 20:45:08

Author of last update: Melvin.boenninger