Difference between revisions of "YpqP"
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=== Additional information=== | === Additional information=== | ||
| − | * rearrangement (deletion of the [[SP-beta prophage]] and generation of the ''spsM'' gene) occurs during [[sporulation]] to allow production of spore polysaccharide {{PubMed|25299644}} | + | * rearrangement (deletion of the [[SP-beta prophage]] and generation of the ''spsM'' gene) occurs during [[sporulation]] and in response to DNA damage to allow production of spore polysaccharide {{PubMed|25299644}} |
=The protein= | =The protein= | ||
Revision as of 08:28, 10 October 2014
- Description: C-terminal part of the split gene spsM (together with yodU), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage
| Gene name | ypqP |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | spore envelope polysaccharide biosynthesis |
| Gene expression levels in SubtiExpress: ypqP | |
| MW, pI | - , - |
| Gene length, protein length | 606 bp, SpsM: 341 aa |
| Immediate neighbours | sprA, msrB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
membrane proteins, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU21670
Phenotypes of a mutant
Database entries
- BsubCyc: BSU21670
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- rearrangement (deletion of the SP-beta prophage and generation of the spsM gene) occurs during sporulation and in response to DNA damage to allow production of spore polysaccharide PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): EpsC (for SpsM)
Extended information on the protein
- Kinetic information:
- Domains: SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU21670
- Structure:
- UniProt: P54183
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ypqP (accoriding to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kimihiro Abe, Yuta Kawano, Keito Iwamoto, Kenji Arai, Yuki Maruyama, Patrick Eichenberger, Tsutomu Sato
Developmentally-regulated excision of the SPβ prophage reconstitutes a gene required for spore envelope maturation in Bacillus subtilis.
PLoS Genet: 2014, 10(10);e1004636
[PubMed:25299644]
[WorldCat.org]
[DOI]
(I e)
