Difference between revisions of "YodU"
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=== Additional information=== | === Additional information=== | ||
− | * rearrangement (deletion of the [[SP-beta prophage]] and generation of the spsM gene) occurs during [[sporulation]] to allow production of spore polysaccharide {{PubMed|25299644}} | + | * rearrangement (deletion of the [[SP-beta prophage]] and generation of the spsM gene) occurs during [[sporulation]] and in response to DNA damage to allow production of spore polysaccharide {{PubMed|25299644}} |
=The protein= | =The protein= |
Revision as of 08:28, 10 October 2014
- Description: , N-terminal part of the split gene spsM (together with ypqP), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage
Gene name | yodU |
Synonyms | ypqP |
Essential | no |
Product | unknown |
Function | spore envelope polysaccharide biosynthesis |
Gene expression levels in SubtiExpress: yodU | |
MW, pI | 15 kDa, 9.819 |
Gene length, protein length | 423 bp, 141 aa (SpsM: 341 aa) |
Immediate neighbours | phy, yotN |
Gene sequence (+200bp) | Protein sequence |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU19810
Phenotypes of a mutant
Database entries
- BsubCyc: BSU19810
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
- rearrangement (deletion of the SP-beta prophage and generation of the spsM gene) occurs during sporulation and in response to DNA damage to allow production of spore polysaccharide PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): EpsC (for SpsM)
Extended information on the protein
- Kinetic information:
- Domains: SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- BsubCyc: BSU19810
- Structure:
- UniProt: O34490
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kimihiro Abe, Yuta Kawano, Keito Iwamoto, Kenji Arai, Yuki Maruyama, Patrick Eichenberger, Tsutomu Sato
Developmentally-regulated excision of the SPβ prophage reconstitutes a gene required for spore envelope maturation in Bacillus subtilis.
PLoS Genet: 2014, 10(10);e1004636
[PubMed:25299644]
[WorldCat.org]
[DOI]
(I e)