motI

motI
168

c-di-GMP receptor protein, inhibits flagellar rotation at high c-di-GMP concentrations

Locus
BSU_22910
Molecular weight
24.98 kDa
Isoelectric point
7.88
Protein length
217 aaSequenceBlast
Gene length
654 bpSequenceBlast
Function
control of MotA activity
Product
c-di-GMP receptor protein
Essential
no
Synonyms
motI, dgrA, ypfA, jofA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5581 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,397,019 → 2,397,672
The protein
Domains
contains a C-terminal PilZ domain (aa 98-203) PubMed
Cofactors
c-di-GMP PubMed
Structure
5VX6 (PDB) (complex with c-di-GMP) PubMed
P38491 (AlphaFold)
Effectors of protein activity
binding of c-di-GMP stimulates the inhibitory interaction with MotA PubMed
Localization
forms MotA-dependent spots at the membrane PubMed
Expression and Regulation
Operons
Genes
motI-ypfB-cmk-rpsA-fni
Description
PubMed
Open in new tab

motI→fni

2025-03-17 18:30:36

Jstuelk

151

40589d593f2ed9acd667e06cee390577206bc679

B16C0E2FDCD0AB8461F12841F5F6E879CEC5BE2C

Genes
motI-ypfB-cmk-rpsA
Description
PubMed
Open in new tab

motI→rpsA

2025-03-17 13:51:16

Jstuelk

90

e8404d7a4ece2ad33ad4f2d223369df3e684ff6d

BB9E8E7CE0132FE9AD9D01FF7333E5A2FF968CEF

Biological materials
Mutant
MGNA-A419 (ypfA::erm), available at the NBRP B. subtilis, Japan
BKE22910 (ΔmotI::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGACTTCACTCTTTCGC,  downstream forward: _UP4_TAAACATCGGCAAACACTTC
BKK22910 (ΔmotI::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGACTTCACTCTTTCGC,  downstream forward: _UP4_TAAACATCGGCAAACACTTC
References
Reviews
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Original Publications
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C194336ED96FA844FFE9FB43BE59ADC5D6DDB3BE

Page visits: 3258

Time of last update: 2025-04-10 07:20:18

Author of last update: Christoph.elfmann