Difference between revisions of "ArsR"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' arsenic resistance operon repressor <br/><br/>
+
* '''Description:''' transcriptional regulator of the [[transcription factors of the ArsR family|ArsR family]], arsenic resistance operon repressor <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor
+
|style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor [[transcription factors of the ArsR family|ArsR family]]
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of as (III) efflux
+
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of As (III) efflux
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25810 arsR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25810 arsR]
Line 37: Line 37:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 70: Line 66:
  
 
=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
Line 80: Line 73:
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:'''
+
* '''Protein family:''' [[transcription factors of the ArsR family|ArsR family]]
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''

Revision as of 10:48, 13 June 2014

  • Description: transcriptional regulator of the ArsR family, arsenic resistance operon repressor

Gene name arsR
Synonyms yqcJ
Essential no
Product transcription repressor ArsR family
Function regulation of As (III) efflux
Gene expression levels in SubtiExpress: arsR
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 12 kDa, 4.883
Gene length, protein length 315 bp, 105 aa
Immediate neighbours yqcK, yqcI
Sequences Protein DNA DNA_with_flanks
Genetic context
ArsR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ArsR expression.png















Categories containing this gene/protein

transcription factors and their control, resistance against toxic metals, Skin element

This gene is a member of the following regulons

ArsR regulon, SigF regulon

The ArsR regulon

The gene

Basic information

  • Locus tag: BSU25810

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the forespore (SigF) PubMed
    • expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) (ArsR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)

Charles M Moore, Ahmed Gaballa, Monica Hui, Rick W Ye, John D Helmann
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Mol Microbiol: 2005, 57(1);27-40
[PubMed:15948947] [WorldCat.org] [DOI] (P p)

T Sato, Y Kobayashi
The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite.
J Bacteriol: 1998, 180(7);1655-61
[PubMed:9537360] [WorldCat.org] [DOI] (P p)