Difference between revisions of "YkuN"
| Line 83: | Line 83: | ||
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' FMN |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 117: | Line 117: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed unless the cells enter an iron starvation ([[Fur]]) {{PubMed|12354229}} | ** repressed unless the cells enter an iron starvation ([[Fur]]) {{PubMed|12354229}} | ||
| + | ** expressed under anaerobic conditions ([[ResD]]) {{PubMed|24214949}} | ||
| + | ** induced by nitric oxide under anaerobic conditions ([[NsrR]]) {{PubMed|24214949}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[Fur]]: transcription repression {{PubMed|12354229}} | ** [[Fur]]: transcription repression {{PubMed|12354229}} | ||
| + | ** [[ResD]]: transcription activation {{PubMed|24214949}} | ||
| + | ** [[NsrR]]: transcription repression {{PubMed|24214949}} | ||
| + | |||
| + | * '''Regulatory mechanism:''' | ||
| + | |||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 15:31, 26 May 2014
- Description: flavodoxin, binds FMN, replaces ferredoxin under conditions of iron limitation, probably involved in electron transfer to nitric oxide synthase
| Gene name | ykuN |
| Synonyms | |
| Essential | no |
| Product | flavodoxin |
| Function | electron transfer |
| Gene expression levels in SubtiExpress: ykuN | |
| Interactions involving this protein in SubtInteract: YkuN | |
| Metabolic function and regulation of this protein in SubtiPathways: ykuN | |
| MW, pI | 17 kDa, 3.827 |
| Gene length, protein length | 474 bp, 158 aa |
| Immediate neighbours | ccpC, ykuO |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14150
Phenotypes of a mutant
Database entries
- BsubCyc: BSU14150
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: flavodoxin-like domain (according to Swiss-Prot)
- Paralogous protein(s): YkuP
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactors: FMN
- Effectors of protein activity:
Database entries
- BsubCyc: BSU14150
- Structure:
- UniProt: O34737
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
