Difference between revisions of "YukE"
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| − | * '''Description:''' secreted protein of the WXG100 superfamily <br/><br/> | + | * '''Description:''' secreted protein of the WXG100 superfamily, homolog of virulence factor EsxA <br/><br/> |
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| − | <pubmed>15576783 22383849 11973144 23861817 23861817 15378759</pubmed> | + | <pubmed>15576783 22383849 11973144 23861817 23861817 15378759 24798022 24696501 21395229</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 06:50, 8 May 2014
- Description: secreted protein of the WXG100 superfamily, homolog of virulence factor EsxA
| Gene name | yukE |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | unknown |
| Gene expression levels in SubtiExpress: yukE | |
| MW, pI | 8 kDa, 7.909 |
| Gene length, protein length | 240 bp, 80 aa |
| Immediate neighbours | yukD, adeR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
proteins of unknown function, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31910
Phenotypes of a mutant
Database entries
- BsubCyc: BSU31910
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: WXG100 superfamily (pfam06013) PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Interactions:
- forms dimers PubMed
Database entries
- BsubCyc: BSU31910
- Structure:
- UniProt: C0SP85
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium): 1775 PubMed
- number of protein molecules per cell (complex medium with amino acids, without glucose): 23591 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 10799 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 11580 PubMed
- number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 4748 PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Laura A Huppert, Talia L Ramsdell, Michael R Chase, David A Sarracino, Sarah M Fortune, Briana M Burton
The ESX system in Bacillus subtilis mediates protein secretion.
PLoS One: 2014, 9(5);e96267
[PubMed:24798022]
[WorldCat.org]
[DOI]
(I e)
Jan Muntel, Vincent Fromion, Anne Goelzer, Sandra Maaβ, Ulrike Mäder, Knut Büttner, Michael Hecker, Dörte Becher
Comprehensive absolute quantification of the cytosolic proteome of Bacillus subtilis by data independent, parallel fragmentation in liquid chromatography/mass spectrometry (LC/MS(E)).
Mol Cell Proteomics: 2014, 13(4);1008-19
[PubMed:24696501]
[WorldCat.org]
[DOI]
(I p)
Catarina Baptista, Hugo Condessa Barreto, Carlos São-José
High levels of DegU-P activate an Esat-6-like secretion system in Bacillus subtilis.
PLoS One: 2013, 8(7);e67840
[PubMed:23861817]
[WorldCat.org]
[DOI]
(I e)
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Sandra Maass, Susanne Sievers, Daniela Zühlke, Judith Kuzinski, Praveen K Sappa, Jan Muntel, Bernd Hessling, Jörg Bernhardt, Rabea Sietmann, Uwe Völker, Michael Hecker, Dörte Becher
Efficient, global-scale quantification of absolute protein amounts by integration of targeted mass spectrometry and two-dimensional gel-based proteomics.
Anal Chem: 2011, 83(7);2677-84
[PubMed:21395229]
[WorldCat.org]
[DOI]
(I p)
Carlos São-José, Catarina Baptista, Mário A Santos
Bacillus subtilis operon encoding a membrane receptor for bacteriophage SPP1.
J Bacteriol: 2004, 186(24);8337-46
[PubMed:15576783]
[WorldCat.org]
[DOI]
(P p)
Christine Eymann, Annette Dreisbach, Dirk Albrecht, Jörg Bernhardt, Dörte Becher, Sandy Gentner, Le Thi Tam, Knut Büttner, Gerrit Buurman, Christian Scharf, Simone Venz, Uwe Völker, Michael Hecker
A comprehensive proteome map of growing Bacillus subtilis cells.
Proteomics: 2004, 4(10);2849-76
[PubMed:15378759]
[WorldCat.org]
[DOI]
(P p)
Mark J Pallen
The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system?
Trends Microbiol: 2002, 10(5);209-12
[PubMed:11973144]
[WorldCat.org]
[DOI]
(P p)
